Download Is it time to stop characterizing the link between

The AdverseEvents Monitor:
Is it time to stop characterizing the link between Impulsive Control Disorders
and dopamine-related drugs as “rare”?
Dramatic side-effects linked to Restless Leg Syndrome and Parkinson’s Disease medications.
Context
Impulse Control Disorders (ICDs), such as Pathological Gambling (PG), hyper-sexuality, and compulsive
shopping, are seldom-studied adverse events because researchers and consumers do not typically associate them
with prescription drugs.
Objectives
1) To identify and analyze adverse event reports from the US Food and Drug Administration's Adverse Events
Database (AERS) that links prescription medications used to treat Parkinson’s Disease and Restless Leg Syndrome
with ICDs. 2) To determine if associations between such behaviors and specific drugs and/or drug classes warrant
greater attention from regulatory bodies, healthcare providers, and consumers. 3) To determine differences, if any,
between specific drugs within the dopamine agonist class of medications.
Methodology
RxFilterTM, a proprietary 17-step data refinement process developed by AdverseEvents, Inc., was used to perform a
comprehensive analysis of ICD-related reports listed in AERS. Drugs were included that had 6 or more ICDs
reported within the time period of January 1, 2004 to March 31, 2011. Adult subjects treated with at least one
dopamine-related medication for Parkinson’s disease, Restless Leg Syndrome, depression, and other conditions
were included. Dopamine agonists included: Mirapex, Requip, Dostinex, Parlodel, Neupro, and Apokyn, and
included generic equivalents and foreign designations. Search criteria included the following adverse events:
impulsive behavior, pathological gambling, hyperphagia (binge eating), compulsive shopping, and hyper-sexuality
(please see Methods section for further detail).
Results
We identified 1,931 primary cases and 2,051 total cases of general ICDs and 1,338 primary cases and 1,363 total
cases of gambling reportedly linked to dopamine-related drugs. One aspect of our calculations included a factoring
step intended to compensate for underreporting of these particularly embarrassing adverse events. Such
calculations estimated average incidence rates of 1.99% for ICDs, and 1.42% for PG in patients treated with
dopamine agonists. Notable ICD / PG rates included: 5.11% / 4.03% for Mirapex; 0.88% / 0.53% for Requip; and
1.19% / 0.77% for Neupro. The evidence of an association with ICDs appeared weaker for levodopa-related drugs.
Finally, co-administration of a dopamine agonist drug was associated with almost all ICD cases we found linked to
either monoamine oxidase or COMT inhibitor treatments.
Conclusions
Pathological gambling and related ICDs are serious adverse drug events associated with prescription medications
used to treat Parkinson’s Disease and restless leg syndrome. Use of the RxFilterTM process indicated that certain
dopamine-related drugs used to treat Restless Leg Syndrome, Parkinson’s Disease, and other related conditions
were significantly linked to serious Impulse Control Disorders (ICDs) such as Pathological Gambling (PG), hypersexuality, and compulsive shopping. Estimated prevalence of these serious ICD side effects reached noteworthy
heights across the dopamine agonist class. Surprisingly, one medication, Mirapex, even reached a 5% estimated
incidence rate. Other dopamine-related drug classes such as MAO, COMT, and levodopa, however, showed lower
percentages of such behavioral modifications. These findings indicate notable ICD and PG associations across
Parkinson’s Disease and restless leg syndrome treatments, as well as within the class of dopamine agonists. While
consensus in the literature still appears to classify these ICD side-effects as rare, our analysis of post-approval
adverse events suggests they are quite common. Prospective studies, however, are needed to establish the exact
incidence of these adverse events and to determine differences between drugs and drug class effects. This analysis
warrants the attention of all healthcare providers and patients associated with dopamine-related medications,
Parkinson’s Disease, and Restless Leg Syndrome.
www.AdverseEvents.com
Parkinson’s Disease
Approximately 1 in every 200 people living in a
developed country has Parkinson’s Disease (PD)1 and
almost 60,000 new cases are diagnosed each year in
the United States alone. As one ages, the chances of
being afflicted with PD significantly increase.
Government studies have predicted that by 2035 the
world will have ~9 million people suffering from
Parkinson’s.
The symptoms of PD such as tremor, movement
disorders, and rigidity are believed to be triggered by
a reduction in neuronal activity mediated by the
endogenous neurochemical dopamine.
Normally, dopamine is secreted by neurons within
specific regions of the brain and such activity forms
part of a functional circuit connected to lower
brainstem areas that, in turn, control orderly
movement behaviors. In Parkinson’s Disease,
however, such dopaminergic innervations are either
decreased or absent. This specific lack of neuronal
activity renders typical movement control impossible.
Levodopa and Dopamine Agonist Drugs
Levodopa (L-Dopa) is a chemical precursor to
dopamine that can be administered to a patient in
order to increase dopamine levels in the brain. LDopa serves as an effective treatment for motor
difficulties and symptoms associated with PD. The
use of L-Dopa, however, is associated with the
development of various dyskinesias and motor
fluctuations.
Accordingly, levodopa is not commonly prescribed
until patients experience significant PD-related
functional disabilities. To delay the start of levodopa
treatment, as well as to attempt to lessen side-effects
once it is prescribed, doctors typically choose to give
patients either monoamine oxidase inhibitors or
“dopamine agonists”.
The dopamine agonist class of drugs binds to the
same neuronal receptor sites as naturally occurring
dopamine. This drug class includes non-synthetic and
synthetic chemicals designed to exert positive effects
by recreating positive dopaminergic drive within the
brain. Dopamine agonists have proven to be a viable
treatment option for various dopamine deficiencies
including Parkinson’s disease, restless leg syndrome,
hypertension, and depression.
Side Effects of Dopamine Agonists
The effects mediated by dopaminergic drive,
however, are not just tightly confined to the control
of movement. They can also influence behavioral
activities. It may be due, in part, to such non-motor
effects that dopamine agonist medications have been
implicated in a number of adverse side effects,
including complex and detrimental behavioral
modifications.
One of these noted changes is a triggering of Impulse
Control Disorders (ICDs)2, including Pathological
Gambling (PG), an extreme behavior that can have
deleterious, life-changing effects on both the victim
and their family members. PG, however, has only
recently been studied as an adverse event triggered
by prescription medications3-9.
Even though the evidence is mounting that ICD and
PG rates should be a substantial factor in determining
the suitability of dopamine agonist use for a given
patient, the National Institute of Neurological
Disorders and Stroke (NINDS) still has an active
website stating that the associated ICD risk is
“rare”10.
Recent reviews cite prevalence rates for pathological
gambling in the general population from 0.43% to
1%. The estimated prevalence of PG in Parkinson’s
patients, however, ranges from 1% to 7%.
Weintraub, et al.2 reported that "dopamine agonist
treatment in PD is associated with 2- to 3.5-fold
increased odds of having an ICD. This association
represents a drug class relationship across ICDs".
Other studies with PD patients also demonstrated
significant ICD rates of up to 3.2%. Interestingly, in
PD patients that were treated with dopamine agonists,
the rate of pathological gambling increased to an
alarming 5.7%9.
(It should be noted that these percentage rates are
www.AdverseEvents.com
from a controlled trail where patients met a
diagnostic criteria for PG. Reported adverse events
from a non-clinical (general population) setting will
be significantly less. In fact, the FDA has estimated
that approximately 90% of all adverse events go
unreported. In our view, this magnitude of
underreporting seems especially likely for ICDs
because of embarrassment factors for those afflicted.)
Such behavioral issues are not confined to just the PD
patient population. For example, other reports have
described ICDs triggered by dopamine agonists in
subjects treated for restless leg sydrome11 and
fibromyalgia12.
In summary, we believe that AE reports of ICDs
triggered by dopamine agonists are both widespread
and significantly underreported and, therefore, such
AE’s should no longer be referred to as “rare”.
Current drug labeling warnings characterize ICD
risks as infrequent, and likely to be a general effect
across the entire class of dopamine-related drugs.
Our intial analysis of the FDA’s AERS database,
however, indicated that significant risk differentiation
may exisits across dopamine-related drugs, and even
within the dopamine agonist class itself.
Accordingly, the current investigation was designed
to use the RxFilterTM process to assess possible
relationships between ICDs across dopaminergic
drugs, as well as within the dopamine agonist class of
FDA-approved medications.
It should be recognized that, as with all retrospective
studies, the information and analysis herein should
only be considered supportive. Prospective studies
are needed to assert clear cause-and-effect
relationships.
AERS database in order to accurately identify and
aggregate all case reports for each marketed drug.
Each drug name variant that includes words such as
the generic name, name outside the US, misspellings,
dosage description, etc., as originally entered in the
AERS database, is consolidated into to one singular
“Brand Name” by RxFilterTM. For instance, Mirapex
has 223 different designations that have been
consolidated into one Brand Name by the RxFilterTM
process. Our analysis included all such variants
(please see Appendix A).
Searching and Analysis: RxFilterTM, a proprietary 17step data refinement process developed by
AdverseEvents, Inc., was used to perform a
comprehensive analysis of dopaminergic drug-linked
adverse events found in AERS. A detailed search of
the AERS database, and accompanying case report
forms, was performed on these drugs in order to
identify potentially important treatment-related side
effects (please see Appendix B).
Finding Adverse Event Case Reports: To determine
the number of case reports associated with each drug,
we used the advanced searching tools of RxFilterTM
to cross-reference the consolidated Brand Name with
suspected cases of ICD-related abnormalities listed in
AERS (please see Appendix B). Note that searches
were not refined by condition or outcome type, as
those fields are often left blank in the FDA AERS
case reports as filed.
Drugs Selected: Apokyn, Azilect, Comtan, Dostinex,
Exelon, Lodosyn, Mirapex, Neupro, Parlodel,
Requip, Sinemet, Stalevo, Symmetrel, Tasmar, and
Zelapar.
Adverse Events Selected: Please see Appendix B.
Methods
Class Designations: Drugs included in this report
have been organized into the following mechanisms
of action:
Data Source and Date Range: Data were obtained
from the FDA AERS database from case reports
received by the FDA between January 1, 2004 and
March 31, 2011, a total of over seven years.
Dopamine Agonists: Apokyn, Dostinex, Mirapex (IR
and ER), Neupro, Parlodel, and Requip (IR and XL).
Drug Name(s) Reorganization: One aspect of the
RxFilterTM process entails reorganization of the
MAO Inhibitors: Azilect and Zelapar.
Levodopa-Related: Sinemet, Stalevo, and Lodosyn.
www.AdverseEvents.com
COMT Inhibitors: Stalevo and Tasmar.
Cholinesterase Inhibitor: Exelon.
Estimated Number of Patients Taking a Given Drug:
To estimate the number of patients taking each drug
during the applicable time period, we used U.S.
prescription figures from IMS, the leading provider
of information services for the healthcare industry.
We estimated the maximum monthly prescription
rate by taking the highest quarterly prescription rate
for each drug as reported by IMS and divided those
figures by 3. We then used that monthly number as
the total number of patients exposed to each drug
between 2006 and 2011, as all of these drugs are
prescribed on a longer term basis.
Indvidual Drug Exposure Estimates: Apokyn = N/A;
Azilect = 29,667; Comtan = 24,667; Dostinex = N/A;
Exelon = N/A; Lodosyn = 3,667; Mirapex = 268,667;
Neupro = 14,333; Parlodel = 26,667; Requip =
432,667; Sinemet = 405,000; Stalevo = 33,000;
Symmetrel = 107,667; Tasmar = 1,000; and Zelapar
= 19,667.
Factoring: Compulsive behaviors, in particular, may
be even more underreported than usual as they: 1)
generally do not result in hospitalization, and 2) carry
stigmas that may cause the patient to be unwilling to
disclose them. Therefore, one aspect of our analysis
includes a factoring step where the raw number of
reported ICDs was multiplied by 10 to compensate
for the estimate that only 10% of adverse events are
actually recorded in the FDA AERS database.
Potential Limitations of this Study
The FDA AERS database is only as accurate as the
information inputted into it from various sources. By
design, it does not filter, correct, or make any
analysis of the quality or potential bias of the inputted
data. The FDA has also estimated that only
approximately 10% of all adverse events that are
potentially triggered by post-marketed drugs are
recorded into AERS.
analyzing AERS data, the output is constrained by
the raw data that can be queried from AERS. For
example, case reports that are submitted to the FDA
often contain mistakes including: spelling errors
leading to misclassifications, important data either
missing or inadequately reported, and duplicate
reports. RxFilterTM utilizes multiple processing steps,
safeguards, and manual oversight to lessen the impact
of such complications, but not all data issues can be
completely fixed.
Results
Analysis with the RxFilterTM process estimated rates
of ICDs, and PG in particular, to be an average of
0.28% and 0.12% for the monoamine oxidase class of
drugs, and 0.43% and 0.18% for levodopa-related
medications, respectively. In contrast, the dopamine
agonist class of drugs had average rates of 1.99% and
1.42%.
Impulsive Control Disorders
Adverse events searched: Please see Appendix B.
There were 2,034 primary cases and 2,157 total cases
listed in AERS, across dopamine-related drugs in the
database. The case reports were:
Drug Name
AEs
Primary / All
Percent Risk
Estimated Risk
Mirapex
1,373 / 1,471
0.51%
5.11%
Requip
379 / 510
0.09%
0.88%
Dostinex
52 / 84
N/A
N/A
Exelon
52 / 69
N/A
N/A
Sinemet
49 / 337
0.01%
0.12%
Stalevo
39 / 112
0.12%
1.18%
Comtan
24 / 125
0.10%
0.97%
Parlodel
21 / 35
0.08%
0.79%
Neupro
17 / 25
0.12%
1.19%
Apokyn
11 / 19
N/A
N/A
Zelapar
7 / 115
0.04%
0.36%
Azilect
6 / 44
0.02%
0.20%
Symmetrel
3 / 133
0.00%
0.03%
Tasmar
1 / 13
0.10%
1.00%
Lodosyn
0 / 11
0.00%
0.00%
TM
Accordingly, while we believe that the RxFilter
process employed by AdverseEvents, Inc. represents
an exceptionally useful tool for searching and
www.AdverseEvents.com
The impulsive control disorder case reports for three
classes of the dopamine-related drugs were:
Drug Class
AEs
Primary / All
Percent Risk
Estimated
Risk
Dopamine Agonist
1,853 / 1,995
0.20%
1.99%
L-Dopa
88 / 400
0.04%
0.43%
MAO
13 / 150
0.03%
0.28%
Pathological Gambling
Adverse events searched: gambling, pathological
gambling. There were 1,414 primary cases and 1,433
total cases listed in AERS, across dopamine-related
drugs in the database. The case reports were:
Drug Name
AEs
Primary / All
Percent Risk
Estimated Risk
Mirapex
1,082 / 1,128
0.40%
4.03%
Requip
229 / 314
0.05%
0.53%
Dostinex
31 / 47
N/A
N/A
Sinemet
25 / 221
0.01%
0.06%
Stalevo
16 / 76
0.05%
0.48%
Neupro
11 / 15
0.08%
0.77%
Parlodel
9 / 13
0.03%
0.34%
Zelapar
4 / 81
0.02%
0.20%
Comtan
4 / 71
0.02%
0.16%
Apokyn
2/4
N/A
N/A
Azilect
1 / 24
0.00%
0.03%
Exelon
0/1
N/A
N/A
Symmetrel
0 / 75
0.00%
0.00%
Tasmar
0 / 10
0.00%
0.00%
Lodosyn
0 / 10
0.00%
0.00%
The gambling case reports for three classes of the
dopamine-related drugs were:
Drug Class
AEs
Primary / All
Percent Risk
Estimated
Risk
Dopamine Agonist
1,364 / 1,416
0.14%
1.42%
41 / 254
0.02%
0.18%
5 / 96
0.01%
0.12%
L-Dopa
MAO
Discussion
Mirapex, one of the most widely prescribed
dopamine agonist drugs, won FDA approval in 1997.
Since that time, hundreds of Mirapex users have
claimed that they developed compulsive behaviors,
namely pathological gambling. Notably, the urges
allegedly ceased when Mirapex was discontinued.
Additionally, in almost all cases, the individual
reporting such changes had no related behavioral
issues prior to taking the medication.
At first, the manufacturer denied any link between
their drug and impulsive behavior. Signs may have
been available, however, from clinical trial results as
early as the mid 1990’s. Numerous lawsuits have
been filed against the manufacturer of Mirapex, and
large sums of money have been paid out to affected
patients. Interestingly, components of such
settlements have been to directly pay off past
gambling debts.
The Mirapex story helped to foster a general view
that the entire class of dopamine-related drugs might
trigger increases in compulsive behaviors.
Accordingly, manufacturers of other dopamine
agonists, and even drugs with completely different
mechanisms of action, scrambled to disclose
warnings about the possibilities for compulsive
tendencies.
While we appreciate the legal reasons why such
warnings were issued, our preliminary analysis using
the RxFilterTM process discussed herein suggests that
there are wide discrepancies in the magnitude of
behavioral risks across dopamine-related
medications, and even notable differences within the
dopamine agonist class of drugs.
Monoamine oxidase inhibitors and levadopa-related
medications have significantly lower rates of ICD
issues when compared to the dopamine agonist class
of drugs. For the agonists in particular, our analysis
suggests that Requip, Apokyn, Dostinex, and Neupro
carry notable risks for behavioral disruptions, but
they are significantly less than Mirapex.
Finally, this investigation calls into question the
notion that ICDs are rare occurrences with dopaminerelated drug regimens. In sharp contrast, the analysis
via the RxFilterTM process indicated significant
frequencies for these adverse events that, if
confirmed by further study, may require review from
regulatory bodies.
www.AdverseEvents.com
In fact, after our initial analysis was completed we
found a freshly published paper with impulse
disorder rates that mesh with our suspicion that
dopamine-related ICDs are likely far more prevalent
than most healthcare providers and consumers
suspect. In a study of 321 PD patients by Hassan et
al.13, ICDs “occurred in 16% of agonist-treated
patients; however, when assessing patients whose
dose was at least minimally in the therapeutic range,
the frequency jumped to 24%”.
Ahlskog JE. Dopamine agonist-triggered pathological behaviors: Surveillance in
the PD clinic reveals high frequencies. Parkinsonism Relat Disord. 2011 May
17(4):260-4.
It should be noted that while the findings presented
here indicate areas of potential interest, prospective
studies are needed to establish the exact incidence of
these adverse events.
References
1. Koroll M, Tanner CM. Epidemiology of Parkinson's disease: an overview. In:
Ebadi M, Pfeiffer FR, eds. Parkinson's disease. Boca Raton: CRC Press,
2005:39-50.
2. Weintraub D, Koester J, Potenza MN, Siderowf AD, Stacy M, Voon V,
Whetteckey J, Wunderlich GR, Lang AE. Impulse control disorders in
Parkinson disease: a cross-sectional study of 3090 patients. Arch Neurol. 2010
May;67(5):589-95.
3. Dodd ML, Klos KJ, Bower JH, Geda YE, Josephs KA, Ahlskog JE.
Pathological gambling caused by drugs used to treat Parkinson's disease. Arch
Neurol 2006;62:1377-81.
4. Wong SH, Steiger MJ. Pathological gambling in Parkinson's disease. BMJ.
2007 Apr 21;334 (7598):810-1.
5. Ferrara JM, Stacy M. CNS Impulse-control disorders in Parkinson's disease.
Spectr. 2008 Aug;13(8):690-8.
6. Fenu S, Wardas J, Morelli M. Impulse control disorders and dopamine
dysregulation syndrome associated with dopamine agonist therapy in
Parkinson's disease. Behav Pharmacol. 2009 Sep; 20(5-6):363-79.
7. Voon V, Fernagut PO, Wickens J, Baunez C, Rodriguez M, Pavon N, Juncos
JL, Obeso JA, Bezard E. Chronic dopaminergic stimulation in Parkinson's
disease: from dyskinesias to impulse control disorders. Lancet Neurol. 2009
Dec;8(12):1140-9.
8. Ceravolo R, Frosini D, Rossi C, Bonuccelli U. Impulse control disorders in
Parkinson's disease: definition, epidemiology, risk factors, neurobiology and
management Parkinsonism Relat Disord. 2009 Dec; 15 Suppl 4:S111-5.
9. Barns Neurauter MP, Rickards H, Cavanna AE. The prevalence and clinical
characteristics of pathological gambling in Parkinson's disease: an evidencebased review. Funct Neurol. 2010 Jan-Mar;25(1):9-13.
10.
www.ninds.nih.gov/disorders/parkinsons_disease/detail_parkinsons_disease.htm
11. Dang D, Cunnington D, Swieca J. The emergence of devastating impulse
control disorders during dopamine agonist therapy of the restless legs syndrome.
Clin Neuropharmacol. 2011 Mar-Apr;34(2):66-70.
12. Holman AJ. Impulse control disorder behaviors associated with pramipexole
used to treat fibromyalgia. J Gambl Stud. 2009 Sep;25(3):425-31.
13. Hassan A, Bower JH, Kumar N, Matsumoto JY, Fealey RD, Josephs KA,
www.AdverseEvents.com
Sales Contact
Adriana Palomino-Scott
V.P. Sales and Business Development
[email protected]
(858) 945-4879
Appendix A
Separate Designations for Dopamine-Related Drugs Listed in the FDA AERS Database
Apokyn
Other names: Apomorphine; Apomine (AU); Apo-Go (UK)
FDA Listed Names (133):
Ago-go (apo-go - Apomorphine Hydrochloride) (not Specified), Apkoin, Apo Morphine, And Hydrochloride, Apo-go, Apo-go (apo-go Pen - Apomorphine Hydrochllorid,
Apo-go (apo-go Pump - Amorphine Hydrochloride), Apo-go (apo-go Pen - Apomorhine Hydrochloride), Apo-go (apokyn) (apomorphine Hydrochloride), Apo-go (ago-go
Pen - Apomorphine Hydrochloride) (not Specified), Apo-go (ampoules (apo-go) (apomorphine Hydrochloride) (apomorphine Hyd, Apo-go (apo-go - Apomophine
Hydrochloride (not Specified), Apo-go (apo-go - Apomophine Hydrochloride) (not Specified), Apo-go (apo-go - Apomorphine Hydrochloaride) (not Specified), Apo-go
(apo-go - Apomorphine Hydrochloride, Apo-go (apo-go - Apomorphine Hydrochloride (not Specified), Apo-go (apo-go - Apomorphine Hydrochloride), Apo-go (apo-go Apomorphine Hydrochloride) (no Specified), Apo-go (apo-go - Apomorphine Hydrochloride) (not Specified), Apo-go (apo-go - Apomorpine Hydrochloride) (not
Specified), Apo-go (apo-go - Apormorphine Hydrochloride) (not Specified), Apo-go (apo-go - Solution For Injection (ampoules) - Apomorphine Hydro, Apo-go (apo-go
Ampoiles 10 Mg/ml Solution For Injection - Apomorphine, Apo-go (apo-go Ampoules - Apomorphine Hydrochloride) (not Specified), Apo-go (apo-go Ampoules 10
Mg/ml - Amomorphine Hydrochloride) (not Spe, Apo-go (apo-go Ampoules 10 Mg/ml - Apomorphine Hydrochloride) (not Spe, Apo-go (apo-go Ampoules 10 Mg/ml
Solution For Injection - Apomorphine, Apo-go (apo-go Ampoules Apomorphine Hydrochloride), Apo-go (apo-go Pen - Apomorphine Hydrochloride, Apo-go (apo-go Pen Apomorphine Hydrochloride), Apo-go (apo-go Pen 10 Mg/ml - Apomorphine Hydrochloride) (not Specifie, Apo-go (apo-go Pen 10 Mg/ml Solution For Injection Apomorphine Hydro, Apo-go (apo-go Pens - Ampomorphine Hydrochloride), Apo-go (apo-go Pfs 5 Mg/ml In Pre-filled Syringe, Apo-go (apo-go Pfs 5 Mg/ml Solution For
Infusion In Pre-filled Syringe, Apo-go (apo-go Pfs 5 Mg/ml Solution For Infusion Pre-filled Syringe -, Apo-go (apo-go Pfs 5 Mg/ml Solution For Injection In Pre-filled
Syring, Apo-go (apo-go Pfs 5 Mg/ml Solution For- Apomorphine Hydrochloride), Apo-go (apo-go Pfs), Apo-go (apo-go Pre-filled Syringe Apomorphine Hydrochloride)
(not Spec, Apo-go (apo-go Pump - Apomorphine Hydrochloride), Apo-go (apo-go Pump - Apomorphine Hydrochloride) (not Specified), Apo-go (apo-go Solution For
Injection (ampoules) 10 Mg/ml - Apomorphin, Apo-go (apo-go Solution For Injection - Apomorphine Hydrochloride) (no, Apo-go (apo-go), Apo-go (apo-go) (apomorphine
Hydrochloride) (apomorphine Hydrochloride, Apo-go (apokyn) (apomorphine Hydrochloride), Apo-go (apomorphine Hcl ), Apo-go (apomorphine Hcl), Apo-go
(apomorphine Hydrochloride), Apo-go (apomorphine Hydrochloride) (apomiorphine Hydrochloride), Apo-go (apomorphine Hydrochloride) (apomorphine, Apo-go
(apomorphine Hydrochloride) (apomorphine Hydrochloride), Apo-go (apomorphine Hydrochloride) (not Specified), Apo-go (apomorphine), Apo-go (pfs (apo-go)
(apomorphine Hydrochloride) (apomorphine Hydrochl, Apo-go - Apomorphie Hydrochloride (not Specified), Apo-go Ampoules, Apo-go Ampoules (apo-go (apomorphine
Hydrochlorid) (apomorphine Hydro, Apo-go Ampoules (apo-go) (apomorphine Hydrochloiride) (apomorphine Hyd, Apo-go Ampoules (apo-go) (apomorphine
Hydrochloride( (apomorphine Hydr, Apo-go Ampoules (apo-go) (apomorphine Hydrochloride), Apo-go Ampoules (apo-go) (apomorphine Hydrochloride) (ampomorphine
Hyd, Apo-go Ampoules (apo-go) (apomorphine Hydrochloride) (apomorphine, Apo-go Ampoules (apo-go) (apomorphine Hydrochloride) (apomorphine Hyd, Apo-go
Ampoules (apo-go) (apomorphine Hydrochloride) (apomorphine Hydr, Apo-go Ampoules (apo-go) (apomorphine Hydrochloride) (apomorpine Hydro, Apo-go Ampoules
(apo-go) (apomorphine Hydrochloride) (apormorphine Hyd, Apo-go Ampoules (apo-go) (apomorphine Hydrochloride)(apomorphine Hydro, Apo-go Ampoules (apo-go)
(apomorphine Hydrochloride0 (apomorphine Hydr, Apo-go Ampoules (apo-go) (apomorphnie Hydrochloride) (apomorphine Hydr, Apo-go Ampoules (apo-go)
(apomorpine Hydrochloride) (apomorphine Hydro, Apo-go Ampoules (apo-go) (apormorphine Hydrochloride) (apormorphine Hy, Apo-go Ampoules (apo-go)(apomorphine
Hydrochloride) (apomorphine Hydro, Apo-go Ampoules (apo-go)(apomorphine Hydrochloride)(apomorphine Hydroc, Apo-go Ampoules (apomorphine Hydrochloride),
Apo-go Ampoules (apomorphine Hydrochloride) (apomorphine Hydrochloride, Apo-go Ampoules M(apo-go) (apomorphine Hydrochloride) (apomorphine Hyd, Apo-go
Ampoules(apo-go)(apomorphine Hydrochloride)(apomorphine Hydroch, Apo-go Pen (apo-go) (apomorphine Hydrochloride) (amoporphine Hydrochlo, Apo-go Pen (apogo) (apomorphine Hydrochloride) (apomorphine Hydrochlo, Apo-go Pen (apo-go)(apomorphine Hydrochloride) (apomorphine Hydrochlor, Apo-go Pen (apomorphine
Hydrochloride), Apo-go Pen(apo-go) (apomorphine Hydrochloride) (apomorphine Hydrochlor, Apo-go Pfs (apomorphine Hydrochloride), Apo-go Pfs (apo-go)
(apomorphine Hydrochloride), Apo-go Pfs (apo-go) (apomorphine Hydrochloride) (apomorphine Hydrochlo, Apo-go Pfs (apo-go) (apomorphine Hydrochloride)
(apomorphine), Apo-go Pfs (apo-go) (apomorphine Hydrochloride) (apormorphine Hydrochl, Apo-go Pfs (apo-go) (apomorphine Hydrochloride)(apomorphine Hydrochlor,
Apo-go Pfs (apo-go) (apomorphine Hydrochlorie) (apomorphine Hydrochlor, Apo-go Pfs (apo-go) (apomorphine Hydrocholride) (apomorphine Hydrochlo, Apo-go Pfs
(apo-go) Apomorphine Hydrochloride) (apomorphine Hydrochlor, Apo-go Pfs (apo-go)(apomorphine Hydrochloride)(apomorphine Hydrochlori, Apo-go Pfs (apomorphine
Hydrochloride), Apo-go Solution For Injection, Apo-go(apo-go Pen - Apomorphine Hydrochloride) (not Specified), Apo-go(apomorphine Hcl)10 Mg/ml Britannia, Apo-go(apo-go - Apomorphine Hydrochloride), Apo-go-ampoules (apo-go) (apomorphine Hydrochloride), Apo-go0 Ampoules (apo-go) (apomorphine Hydrochloride)
(apomorphine Hyd, Apo-goapomorphine Hydrochloride), Apofin - Apomorphine, Apokin (apomorphine Hydrochloride) (apomorphine Hydrochloride), Apokinon,
Apokinon (apomorphine Hydrochloride), Apokyn, Apokyn 3ml Cartridges, Apokyn Injection, Apomine (apomine - Apomorphine Hydrochloride) (not Specified),
Apomorfin, Apomorphin, Apomorphine, Apomorphine (apo-go) (apomorphine Hydrochloride) (apomorphine Hydrochl, Apomorphine (apomorphine), Apomorphine
(pump) (apomorphine), Apomorphine Hcl, Apomorphine Hcl Injection 10 Mg/ml Britannia Pharmaceuticals, Apomorphine Hydrochloride, Apomorphine Hydrochloride (10
Mg/ml), Apomorphine Hydrochloride (ampomorphine Hydrochloride), Apomorphine Hydrochloride (apofin), Apomorphine Hydrochloride (apomorphine - Apomorphine
Hydrochloride ), Apomorphine Hydrochloride (apomorphine - Apomorphine Hydrochloride), Apomorphine Hydrochloride (apomorphine Hydrochloride ), Apomorphine
Hydrochloride (apomorphine Hydrochloride), Apomorphine Hydrochloride (apomorphine Hydrochloride) (10 Mg), Apomorphine Hydrochloride (apomorphine
Hydrochloride) (10 Mg/ml), Apomorphine Hydrochloride Injection, Forum Products Ltd, 41-51 Brighto, Apomorphine Nos (apo-go) (apomorphine Hydrochloride)
(apomorphine Hydr, Apomorphone Hydrochloride, Apomorpine (apomorphine), Apoxyn (apomorphine Hydrochloride), Uprima
Azilect
Other names: Agilect, Rasagiline Mesylate, TVP-1012
FDA Listed Names (35):
Azelect, Azelict, Azilect, Azilect (pasagiline), Azilect (rasagiline Mesylate), Azilect (rasagiline Mesylate) (rasagiline Mesylate), Azilect (rasagiline) (rasagiline Mesylate),
Azilect /01759901/, Azilect /01759902, Azilect /01759902/, Azilect /01759902/ (rasagiline Mesylate), Azilect Rasiogline, Azilect Tablets, Azilect(rasagiline Mesylate),
Azilect/rasagilin Mesilate, Azilezt, Blinded: Rasagiline Mesilate, Rasagaline, Rasagaline 0.5mg Teva, Rasagaline 1mg, Rasagaline 1mg Teva, Rasagaline/placebo, Rasagilin
1mg, Tablets, Rasagiline, Rasagiline (rasagilin), Rasagiline (rasagiline), Rasagiline (rasagline), Rasagiline (tablets), Rasagiline Mesilate, Rasagiline Mesilate (rasagiline
Mesilate), Rasagiline Mesilate Tablet (rasagiline Mesilate), Rasagiline Mesylate, Rasagiline/placebo, Rasagilinmesilate 1mg, Tablets, Rasagline/placebo
www.AdverseEvents.com
Comtan
Other names: Comtess, Entacapone
FDA Listed Names (41):
Camtan (comtess) (tablet) (entacapone), Camtan (comtess) (tablet) (entacapone), Comatan, Comtam, Comtan, Comtan (comtess) (tablet) (entacapone), Comtan
(entacapone), Comtan (entacapone) (entacapone), Comtan (entacapone) (nr), Comtan (entacapone) (ta), Comtan (entacapone) Tablets, Comtan (entacapone0, Comtan
(entcapone), Comtan Cmt+tab, Comtan/entacapon, Comtess, Comtess (entacapone), Comtess (entacapone), Comtess (entacapone), Comtess (entacapone), Comtess #or,
Comtess (comtess - Entacapone), Comtess (entacapone), Comtess (entacapone) (ta), Comtess (entacapone) Unknown, Comtess (entacapone, , 0), Comtess (entacarpone)
(nr), Comtess(entacapone), Entacapne (entacapone0, Entacapon, Entacapon (entacapone), Entacapon (entacapone), Entacapone, Entacapone (comtess) (entacapone),
Entacapone (comtess) (unknown) (entacapone), Entacapone (con.), Entacapone (unknown), Entacapone - Comtan 200 Mg Novartis, Entacapone 200mg, Entacapone Oral
Use 200 Mg, Entacapone Vs Placebo
Dostinex
Other names: Cabergoline
FDA Listed Names (50):
Cabargoline, Cabargoline (cabergoline), Cabaser, Cabaser (cabergoline), Cabaser (cabergoline) Tablet, 1-4mg, Cabaser (cabergoline) (ta), Cabaser (cabergoline) Tablet 1-4
Mg, Cabaser (cabergoline) Tablet, 1-4 Mg, Cabaser (cabergoline) Tablet, 1-4mg, Cabaser (cabergoline)tablet, 1-4mg, Cabaser (carbergoline), Cabaser (gabergoline),
Cabaser(cabergoline) Tablet, 1-4mg, Cabaseril, Cabaseril (cabergoline), Cabaseril (cabergoline, , 0), Cabaseril Regimen #2, Cabaseril(cabergoline) Tablet, 1-4mg,
Cabergoliine, Cabergolin, Cabergoline, Cabergoline (mfr. Unknown), Cabergoline Cabergoline) Unknown, Cabergoline (cabergoline) 1 Mg, Cabergoline (cabergoline)
Tablet, 1-4mg, Cabergoline (formulation Unknown) (cabergoline), Cabergoline (gabergoline), Cabergoline (mfr. Unknown), Cabergoline (tablets), Cabergoline (watson
Laboratories), Cabergoline 1mg, Tablets (cabergoline), Cabergoline 9cabergoline), Cabergoline Tablet (cabergoline), Cabergoline Tablets 0.5 Mg, Cabergoline Vs
Levodopa (code Not Broken), Cabergolne (cabergoline), Caberseril (cabergoline), Carbergoline (cabergoline), Dastinix, Dositinex (cabergoline), Dostinex, Dostinex
(cabergoline) (0.5 Milligram, Tablets) (cabergoline), Dostinex (cabergoline)tablet 0.25-.5 Mg, Dostinex (carbegolide), Dostinex (con.), Dostinex 0.5 (cabergoline), Dostinex
Regimen #2, Dostinex Regimen #3, Sogilen, Sostilar
Exelon
Other names: Rivastigmine Tartrate; Prometax (EU); ENA 713
FDA Listed Names (85):
Blinded Exelon, Ecelon, Ekelon, Ena 713, Erivastigmine, Erivastigmine(), Exalon, Excellon, Excelon, Excelon (rivastigmine), Exeleon, Exelom, Exelon /01383201/
(rivastigmine), Exelon, Exelon /01383201/, Exelon /01383202/, Exelon (3 Mg) (rivastigmine), Exelon (amitriptyline Hcl), Exelon (capsule) (rivastigmine), Exelon
(capsules), Exelon (poultice Or Patch), Exelon (privastigmine Tartrate), Exelon (rivastagmine Tartrate), Exelon (rivastatigmine Tartrate), Exelon (rivastigime Tartrate),
Exelon (rivastigimine Tartrate), Exelon (rivastigine Tartrate), Exelon (rivastigmine Tartrate) (poultice Or Patch), Exelon (rivastigmine Tartrate) (rivastigmine Tartrate),
Exelon (rivastigmine Tartrate) (transdermal) (rivastigmine Tartrate), Exelon (rivastigmine) (rivastigmine), Exelon (rivastigmnie Tartrate), Exelon (rivatatigmine Tartrate),
Exelon (rivstigmine Tartrate), Exelon ({null}), Exelon / 01383201, Exelon /01383201/, Exelon /01383201/ (rivastigmine), Exelon /01383202/, Exelon /sch/, Exelon /sch/
(rivastigmine Tartrate), Exelon 3 Mg, Exelon Exelon+cap, Exelon Exelon+sol, Exelon Exelon+tdp, Exelon Patch, Exelon Patch (rivastigmeine Tartrate), Exelon Patch
(rivastigmine Tartrate), Exelon Patch (rivastigmine Tatrate), Exelon Patch (rivastigmine Transdermal System) 9.5 Mg, Exelone, Exlon, Exolan, Exulon, Prometax, Prometax
(rivastigmine Tartrate), Prometax (rivastigmine), Revastigmine, Revastigmine Tartrate, Rivastigime Tartrate, Rivastigimine, Rivastigine 3mg, Rivastigmin, Rivastigmine,
Rivastigmine (6 Milligram, Tablets), Rivastigmine (pill), Rivastigmine (rivastigmine Tartrate), Rivastigmine (rivastigmine), Rivastigmine (rivastigmine) (rivastigmine),
Rivastigmine (rivastigmine) (tablets) (rivastigmine), Rivastigmine (rivastigmine) 3mg, Rivastigmine (rivastigmine) Unknown, Rivastigmine (tablets), Rivastigmine Hydrog.
Tartr (formulation Unknown) (rivastigmine Hydrog., Rivastigmine Hydrog.tartr, Rivastigmine Hydrogen Tartarate, Rivastigmine Hydrogen Tartrate, Rivastigmine Patch,
Rivastigmine Tartrate, Rivastigmine Tartrate (exelon) Capsules, Rivastigmine Tartrate (rivastigmine Tartrate), Rivastigmine Tartrate (rivastigmine Tartrate0, Rivastigmine
Tartrate (watson Laboratories), Rivastigmine Vs Placebo, Rivastigmine(rivastigmine) (tablet) (rivastigmine)
Lodosyn
Other names: Carbidopa
FDA Listed Names (28):
Cabidopa, Carbadopa, Carbidopa, Carbidopa (carbidopa), Carbidopa (carbidoa), Carbidopa (carbidopa), Carbidopa (carbidopa) 200mg, Carbidopa (caribidopa), Carbidopa
(formulation Unknown) (generic) (carbidopa), Carbidopa (tablets), Carbidopa 100mg, Tablets (carbidopa), Carbidopa 25/100, Carbidopa 50/200, Carbidopa Cr, Carbidopa
Er, Carbidopa Hydrate, Carbidopa Monohydrate, Carbidopal, Carbiodpa, Carbo-dopa, Carbodopa, Carvidopa, Carvodopa, Lodosin, Lodosyn, Lodosyn (unknown), Lodosyn
(carbibopa), Lodosyn Tabs
Mirapex
Other names: Pramipexole, Daquiran, Mirapexin, Sifrol
www.AdverseEvents.com
FDA Listed Names (223):
Bi Sifrol, Bi Sifrol (pramipexole Dihydrochloride), Bi Sifrol (pramipexole Dihydrochloride) Tablet, Bi Sifrol (pramipexole Hydrochloride Hydrate), Bi Sifrol 0.5mg, Bi
Sifrol Tablets (pramipexole Dihydrochloride) (ta), Bi Siprol (pramipexole Dihydrochloride), Bi-sifrol, Bi-sifrol (pramipexole Hydrochloride Hydrate)(pramipex, Bi-sifrol
(pramipexole Dihydrochloride), Bi-sifrol (pramipexole Hydrochloride Hydrate) (pramipexole), Bi-sifrol (pramipexole), Bi-sifrol (pramipezole Dihydrochloride) (ta), Bisifrol 0.5mg, Bi-sifrol Tablets, Bi-sifrol Tablets (pramipexole Dihydrochloride (pramipexole), Bi-sifrol Tablets (pramipexole Dihydrochloride), Bi-sifrol Tablets
(pramipexole Dihydrochloride) (ta), Bi-sifrol Tablets (pramipexole Dihydrochloride) (ta) (pramipexole), Bi-sifrol Tablets (pramipexole Dihydrochloride)(ta), Bi-sifrol
Tablets (pramipexole Dihyrochloride) (ta), Bi-sifrol Tablets(pramipexole Dihydrochloride) (ta), Bi-sifrol Tablets(prampexole Dihydrochloride) (ta), Bi-siprol (pramipexole),
Blinded *pramipexole 2hcl, Blinded Pramipexole 2hcl, Marapex, Maripex, Maripex -mirapex-, Merapax, Merapex, Merepex, Meripax, Meripex, Mirapax, Mirapec,
Mirapex, Mirapex /01356401/, Mirapex (pramipexole Dihydrocloride), Mirapex (pramipexole Sodium), Mirapex Boehinger Ingelheim (pramipexole Dihydrochloride),
Mirapex Pharmacia + Upjohn, Mirapex (0.5 Milligram), Mirapex (blind) Tablets, Mirapex (con.), Mirapex (mirapex), Mirapex (pamipexole), Mirapex (paramipexole
Dihydrochloride), Mirapex (pramipekole Dihydrochloride), Mirapex (pramipexol Dihydrochloride), Mirapex (pramipexole Dihychloride), Mirapex (pramipexole
Dihydrochloloride), Mirapex (pramipexole Dihydrochloride) (pramipexole Dihydrochloride), Mirapex (pramipexole Dihydrochloride) (ta) (pramipexole), Mirapex
(pramipexole Dihydrochloride) , 0.25 Mg, Mirapex (pramipexole Dihydrochloride0, Mirapex (pramipexole Dihydrochoride), Mirapex (pramipexole Dihyradrochloride),
Mirapex (pramipexole) (0.5 Milligram), Mirapex (pramipexole) (tablets), Mirapex (pramiprexole Dihydrochloride), Mirapex (pramiprxole Dihydrochloride), Mirapex
(rpamipexole Dihydrochloride), Mirapex (unknown), Mirapex /01356401/ (pramipexole), Mirapex C Boehringer - Ingelheim, Mirapex Cymb, Mirapex ^boehringer
Ingelheim^ (pramipexole Dihydrochloride), Mirapex ^boehringer Ingelheim^ (prampexole Dihydrochloride, Gel), Mirapex ^pharmacia + Upjohn^, Mirapex ^pharmaciaupjohn^, Mirapex(mirapex), Mirapexin, Mirapexin (apokyn) (pramipexole) (apomorphine Hydrochloride), Mirapexin (mirapexin), Mirapexin (pramipexole
Dhihydrochloride) (ta), Mirapexin (pramipexole Dihychloride), Mirapexin (pramipexole Dihydrochloride), Mirapexin (pramipexole Dihydrochloride) (0.75 Mg), Mirapexin
(pramipexole Dihydrochloride) (ta), Mirapexin (pramipexole Dihydrochloride) (ta) (pramipexole), Mirapexin (pramipexole Dihydrochloride)(pramipexole), Mirapexin
(pramipexole Dijydrochloride), Mirapexin (pramipexole), Mirapexin (suspect), Mirapexin (ta), Mirapexin Tablet, Mirapexin(pramipexole Dihydrochloride) (ta)
(pramipexole), Mirapexin(ta) (pramipexole), Mirapexin, Sifrol, Mirapez, Mirapixine, Miraplex (pramipexole Dihydrochloride), Miraprex (pramipexole Dihydrochloride),
Miraprexin (pramipexole Dihyrochloride), Miripex, Miropex, Mitrapex Tablets (pramipexole Dihydrochloride), Myraprex (pramipexole Dihydrochloride), Parmipexole,
Pramipaxole, Pramipexol, Pramipexol Dihydrochloride (mirapex), Pramipexole, Pramipexole (pramipexole), Pramipexole (pramipexole), Pramipexole (apo-go)
(pramipexole) (apomorphine Hydrochloride), Pramipexole (con.), Pramipexole (ngx), Pramipexole (pill), Pramipexole (praminpexole), Pramipexole (pramipexole
Dihydrochloride), Pramipexole (pramipexole Dihydrochloride) (nr), Pramipexole (pramipexole Dihydrochloride) (nr) (pramipexole), Pramipexole (pramipexole
Dihydrochloride) (pramipexole), Pramipexole (pramipexole Dihydrochloride) (ta), Pramipexole (pramipexole Dihydrochloride) (ta) (pramipexole), Pramipexole
(pramipexole Hydrochloride), Pramipexole (pramipexole), Pramipexole (pramipexole) (pramipexole), Pramipexole (pramipexole) (tablets), Pramipexole (pramipexole)
Unknown, Pramipexole (pramipexole0, Pramipexole (ramipexole) (tablets), Pramipexole (tablets), Pramipexole (uk), Pramipexole (uk) (pramipexole Dihydrochloride),
Pramipexole (uk) (pramipexole Dihydrochloride) (nr), Pramipexole (uk) (pramipexole Dihydrochloride) (nr) (pramipexole), Pramipexole (uk) (pramipexole
Dihydrochloride) (ta), Pramipexole (unknown Until Unknown), Pramipexole (unknown), Pramipexole (watson Laboratories), Pramipexole 0.5mg, Pramipexole 1 Mg
Boehringer Ingelheim, Pramipexole Di-hcl, Pramipexole Diehydrochloride, Pramipexole Dihychlloride, Pramipexole Dihydrochloride, Pramipexole Dihydrochloride (con.),
Pramipexole Dihydrochloride (mirapex), Pramipexole Dihydrochloride (pramipexole Dihydrochloride), Pramipexole Dihydrochloride (pramipexole Dihydrohloride),
Pramipexole Dihydrochloride (pramiprexole Dihydrochloride), Pramipexole Dihydrochloride (unknown), Pramipexole Dihydrochloride -pramipexole-, Pramipexole
Dihydrochloride Monohydrate, Pramipexole Dihydrochloride(tablets), Pramipexole Dihydrochloride), Pramipexole Dihyrochloride (pramipexole Dihydrochloride),
Pramipexole Diphydrochloride, Pramipexole Er, Pramipexole Er (blind), Pramipexole Hcl, Pramipexole Hydrochloride, Pramipexole Hydrochloride Hydrate, Pramipexole
Hydrochloride Hydrate (pramipexole Dihydrochloride), Pramipexole Hydrochloride Monohydrate, Pramipexole Ir (blind), Pramipexole Tablets, Pramipexole Unknown,
Pramipexole(pramipexole Dihydrochloride), Pramipexole-dihydrochloride (pramipexole Dihydrochloride), Pramippxole, Pramiprexole (pramipexole), Priampexole,
Prmipexole, Sifrol, Sifrol /gfr/, Sifrol (pramipexole Dihydrochloride), Sifrol (0,18 Mg, Tablet) (pramipexole Dihydrochloride), Sifrol (framipexole Dihydrochloride), Sifrol
(pramipexole Dihychloride) (ta) (pramipexole), Sifrol (pramipexole Dihydrochloride), Sifrol (pramipexole Dihydrochloride) (1.1 Mg), Sifrol (pramipexole Dihydrochloride)
(pramipexole Dihydrochloride), Sifrol (pramipexole Dihydrochloride) (ta), Sifrol (pramipexole Dihydrochloride) (ta) (pramipexole), Sifrol (pramipexole Dihydrochloride) ,
0.18 Mg, Sifrol (pramipexole Dihydrochloride) Tablets, Sifrol (pramipexole), Sifrol (pramipexole) (0.7 M G), Sifrol (pramipexole) (being Queried), Sifrol (sifrol Pramixole) (not Specified), Sifrol (sifrol) (not Specified), Sifrol (sifrol)(not Specified), Sifrol (ta), Sifrol (ta) (pramipexole), Sifrol (tablets), Sifrol - 0,18 Mg - Tabletten,
Sifrol - 0,35 Mg - Tabletten, Sifrol - 0,7 Mg - Tabletten, Sifrol 0,088 Mg, Sifrol 0,18 Mg, Sifrol 0,7 Mg, Sifrol 0.088mg, Sifrol 0.18, Sifrol 0.35 Mg, Sifrol 0.7 Mg
(pramipexole Dihydrochloride) (ta)(pramipexole), Sifrol 0.7mg, Sifrol 018, Sifrol 1.1mg, Sifrol Lp, Sifrol Retard, Sifrol Retardtablets, Sifrol Tab, Sifrol Tab 0.088 Mg,
Sifrol Tab 0.35 Mg, Sifrol Tab 0.35 Mg (pramipexole Dihydrochloride), Sifrol Tab. 0.18 Mg, Sifrol Tab. 0.18 Mg (pramipexole Dihydrochloride) (ta), Sifrol Tab. 0.7 Mg,
Sifrol Tab. 0.7 Mg(ta) (pramipexole), Sifrol Tab. 1.1 Mg (pramipexole Dihydrochloride ) (ta) (pramipexole), Sifrol Tab. 1.1 Mg (pramipexole Dihydrochloride) (ta), Sifrol
Tablets, Sifrol Tablets (pramipexol Dihydrochloride), Sifrol Tablets (pramipexole Dihydrochloride) (ta) (pramipexole), Sifrol Tablets (ta) (pramipexole), Sifrol(pramipexole
Dihydrochloride (ta), Sifrol(pramipexole Dihydrochloride) (ta), Sifrol-0,008 Mg- Tabletten (pramipexole Dihydrochloride) (ta) (pramipe, Siprol (pramipexole
Dihydrochloride) (ta) (pramipexole)
Neupro
Other names: Rotigotine TDS, Rotigotine CDS, SPM 962, SPM 936
FDA Listed Names (61):
Neupro, Neupro 8mg, Neupro (rotigotine), Neupro (rotigotine) (rotigotine), Neupro 6mg Patch Schwarz, Neupro Patch 4 Mg Schwatz Pharma, Neupro-2mg/ 24h
(rotigotine), Neupro-2mg/24h, Neupro-2mg/24h (rotigotine), Neupro-4mg/ 24h (rotigotine), Neupro-4mg/24 H (rotigotine), Neupro-4mg/24h (rotigotine), Neupro-6mg/ 24h
(rotigotine), Neupro-6mg/24h (rotigotine), Neupro-8mg/24h (rotigotine), Neupro-patch, Neupro-patch (rotigotine), Neupro-patch-dose - Unknown (rotigotine), Neupropatch-dose- (rotigotine), Neupro-patch-dose-(rotigotine), Neupro-patch-dose-unknown, Neupro-patch-dose-unknown (rotigotine), Neuro-patch (rotigotine), Neuro-patchdose (rotigotine), Neuro-patch-dose Unknown (rotigotine), Neuro-patch-dose-unknown (rotigotine), Neurpo-patch-dose-unknown (rotigotine), Rotigotin-20cm - 9mg-patch
(rotigotine), Rotigotine, Rotigotine (dose Unknown) , Patch (silicone) (rotigotine), Rotigotine (dose Unknown) Patch (silicone) (rotigotine), Rotigotine (dose Unknown),
Patch (silicone) (rotigotine), Rotigotine (dose Unknown), Unknown (rotigotine), Rotigotine (dose Unknown0, Unknown (rotigotine), Rotigotine (neopro), Rotigotine
(neupro - Rotigotine), Rotigotine (neupro), Rotigotine (neupro-6mg/24h), Rotigotine (neupro-8mg/24h), Rotigotine (neupro-patch-dose-unknown), Rotigotine (no Pre.
Name), Rotigotine (one Of Rotigotine Or Placebo), Rotigotine (rotigotine), Rotigotine (rotigotine) (lot#s 091807070003), Rotigotine (rotigotine) (lot#s: 051307010002),
Rotigotine (rotigotine) (lot#s: 071005090001), Rotigotine (rotigotine) (lot#s: 512207110004), Rotigotine (rotigotine) Transdermal Patch, Transdermal Patch, Rotigotine
(rottgotine) (lot#s: 091807070003), Rotigotine , Patch (silicone), Rotigotine Patch (silicone), Rotigotine(dose Unknown), Patch (silicone) (rotigotine), Rotigotine(dose
Unknown), Unknown (rotigotine), Rotigotine(rotigotine), Rotigotine, Patch (silicone), Rotigotine-30cm2 -13.5mg-patch (rotigotine), Rotigotine-30cm? -13.5mg-patch
(rotigotine), Rotigotine-40cm -18mg-patch (rotigotine), Rotigotine-40cm? -18mg-patch (rotigotine), Rotigotine-trial, Rutigutine
www.AdverseEvents.com
Parlodel
Other names: Bromocriptine
FDA Listed Names (57):
Apo-bromocriptine (bromocriptine Mesilate), Broman (bromocriptine) (2.5 Milligram, Drops (for Oral Use)) (bromocri, Bromcriptine, Bromergon, Bromergon
(bromocriptine) Tablet, Bromergon (bromocriptine) Tablet, Bromergon (ngx), Bromergon (ngx) (bromocriptine) Tablet, Bromergon (ngx)(bromocriptine) Tablet,
Bromkriptin, Bromo Criptin, Bromo-kin, Bromocrioptine Mesylate (bromocriptine), Bromocriptin, Bromocriptin Mesilate, Bromocriptin-richter, Bromocriptina Dorom
(bromocriptine Mesilate, Bromocriptine Mesilate, B, Bromocriptine, Bromocriptine (formulation Unknown), Bromocriptine 2.5mg Lek, Bromocriptine (bromocriptin),
Bromocriptine (bromocriptin) (bromocriptine), Bromocriptine (bromocriptine) Tablets, Bromocriptine (con.), Bromocriptine (ngx), Bromocriptine (ngx) (bromocriptine),
Bromocriptine (ngx) (bromocriptine) Unknown, Bromocriptine (unknown), Bromocriptine /00412202/ (bromocriptine Mesilate), Bromocriptine 00412202/ (bromocriptine
Mesilate), Bromocriptine 2.5mg Lek, Bromocriptine Mesilate (bromocriptine Besilate), Bromocriptine Mesylate, Bromocriptne, Bromocriptne Mesylate, Bromocripton,
Bromocryptine, Bromocryptine (bromocriptine), Bromocryptine Mesylate, Bromocryptine Mesylate (bromocripitine Mesilate), Bromocrytine Mesylate, Bromodriptine
(bromocriptine), Bromokin, Cycloset, Kripton, Parilodel, Parlodel, Parlodel /00412202/ (bromocriptine Mesilate), Parlodel (bromocriptin Mesilate), Parlodel (unknown),
Parlodel /00412202/, Parlodil, Parodel (bromocriptine Mesilate), Paroldel, Pravidel, Pravidel (bromocriptine Mesilate), Pravidel Tablets
Requip
Other names: Requip Immediate-release, Ropinirole HCl, Repreve, Adartrel (EU)
FDA Listed Names (113):
Adarterl, Adartrel, Gen Requip, Generic Requip, Monograph For Requip In Mosby's Nursing Drug Reference, Rapinerol, Reguip, Repreve, Requib, Requip, Requip
(ropinrole Hydrochloride), Requip (ropinirol Hydrochloride), Requip (3 Milligram), Requip (con.), Requip (contin), Requip (ripinirole Hydrochloride), Requip (robinirole
Hydrochloride), Requip (ropindrole Hydrochloride), Requip (ropiniirole Hydrochloride), Requip (ropiniprole Hydrochloride), Requip (ropinirol Hydrochloride), Requip
(ropinirole Hcl) Gsk, Requip (ropinirole Hydochloride), Requip (ropinirole Hydrochlorde) (ropinirole), Requip (ropinirole Hydrochlordie), Requip (ropinirole
Hydrochloride) (0.5 Milligram), Requip (ropinirole Hydrochloride) (1 Milligram) (ropinirole Hydrochlor, Requip (ropinirole Hydrochloride) (25 Milligram), Requip
(ropinirole Hydrochloride) (ropinirold Hydrochloride), Requip (ropinirole Hydrochloride) (ropinirole Hydrochloride), Requip (ropinirole Hydrochloride) (tablets)
(ropinirole Hydrochloride), Requip (ropinirole Hydrochloride) 2 Mg, Requip (ropinirole Hydrochloride) Tablets, Requip (ropinirole Hydrochloride)(tablet), Requip
(ropinirole Hydrochlorine), Requip (ropinirole Hydrochoride), Requip (ropinirole Hyydrochloride), Requip (ropinorole Hydrochloride), Requip (ropinrole Hydrochloride),
Requip (ropinrole Hydrochloride) (tablets), Requip (rpinirole Hydrochloride), Requip (unknown), Requip 1 Mg. Glaxo Smith, Requip 1.0, Requip 8 Mg Gsk, Requip Depot,
Requip Modutab (ropinirole Hydrochloride) (ropinirole Hydrochloride), Requip Ropinirole (unknown), Requip(ropinrole Hydrochloride), Requip, 0.25 Mg, Filmtabl, Gsk,
Requip. Mfr: Not Specified, Requip. Mfr: Smith Kline Beecham, Requipt, Robinirole, Ropenerol, Ropimrole, Ropinerol, Ropinerole, Ropinerole 0.5 Mg, Ropinirol,
Ropinirol (ropinirole), Ropinirol Hcl, Dose Unknown, Tablets (ropinirole Hydrochloride), Ropinirol Hydrochloride (ropinirole Hydrochloride), Ropinirole, Ropinirole
(ropinirole) (1 Milligrma) (ropinirole ), Ropinirole (con.), Ropinirole (corepharma), Ropinirole (ngx), Ropinirole (pill), Ropinirole (requip) (mfg: Wockhardt Us),
Ropinirole (ropinirol), Ropinirole (ropinirole), Ropinirole (ropinirole) (6 Mg), Ropinirole (ropinirole) (ropinirole), Ropinirole (ropinirole) Unknown, Ropinirole
(ropinorole), Ropinirole 0.5 Mg, Ropinirole 250ug, Ropinirole 2mg, Ropinirole Hcl, Ropinirole Hydrochloride, Ropinirole Hydrochloride (ropinirole Hydrochloride),
Ropinirole Hydrochloride (con.), Ropinirole Hydrochloride (requip), Ropinirole Hydrochloride (ropinirole Hydrochloride), Ropinirole Hydrochloride (ropinrole
Hydrochloride), Ropinirole Hydrochloride Tablet (ropinirole Hcl), Ropinirole Hydrochlorided (ropinirole Hydrochloride), Ropinirole Oral 24 Mg, Ropinirole Tablets
0.25mg, 0.5mg, 1mg, 2mg, 3mg, 4mg, 5mg (base), Ropinirole Tablets 0.25mg, 5mg, 1mg, 2mg, 3mg, 4mg, 5mg (base), Ropinirole [ropinirole]250 Microg (for Restless Leg
Syndrome), Ropiniroloe, Ropinorol, Ropinorole, Ropinorole 0.5 Mg, Ropinorole 1mg Corepharma, Ropinrole, Roppinirole, Requip Cr, Requip Sustained Release, Requip
Tablet-extended Release (ropinirole Hcl), Requip Xl, Requip Xl (ropinirole Extended Release), Requip Xl (ropinirole), Requip Xl 4 Mg Gsk, Requipt Xl, Ropinirol Xl - Skf
101468 4mg Tablet Gsk Comet, Ropinirole (requip Xl), Ropinirole Hydrochlloride (requip Xl), Ropinirole Hydrochloride Tablet-extended Release (generic (ropinirole,
Ropinirole Xl, Ropinirole Xl - Skf 101468 2mg Tablet Gsk Comet
Sinemet
Other names: Carbidopa-Levodopa
FDA Listed Names (412):
(carbidopa 25mg And Levodopa 100mg), (carbidopa, Levodopa), (carbidopa 25mg And Levodopa 100mg), Tablets, (levodopa/carbidopa) 100mg/25mg, Tablets (carbidopa,
Levodopa) (levodo, 1/2 Sinemet Cr, Apo-levocarb (levodopa, Carbidopa), Apo-levocarb (levodopa, Carbidopa), Apo-levocarb (levodopa/carbidopa), Apo-levocarb Cr
(levodopa/carbidopa), Atamet (carbidopa, Levodopa), Cabidopa+levodopa, Cabidopa-levodopa (carbidopa, Levodopa), Cabidopa/levodopa, Cabidopa/levodopa 25/100
Mg/1.5 Tablet/4 Times/day Subistute For Sinme, Carb/levodopa, Carbadopa/levodopa, Carbadopa/levodopa Er Tabs Apo132-50/200 Apotex, Carbid/levodopa,
Carbidoa/levodopa, Carbidoga Levodopa, Carbidop-levodopa, Carbidopa + Levodopa, Carbidopa + Levodopa Cr, Carbidopa + Levodopa Cr Tabs 25/100mg, Carbidopa +
Levodopa Cr Tabs 50/200mg, Carbidopa + Levodopa Tabs 25mg/100mg, Carbidopa + Levodopa Tabs 25mg/250mg, Carbidopa / Levadopa, Carbidopa /levodopa (generic),
Carbidopa 10/levodopa, Carbidopa 25/levodopa, Carbidopa 25mg And Levodopa 100mg, Carbidopa 25mg/levadopa 250mg, Carbidopa 50/kevidopa Sa, Carbidopa
50/levodopa, Carbidopa 50/levodopa 200mg, Carbidopa And Levodopa, Carbidopa And Levodopa (carbidopa, Levodopa), Carbidopa And Levodopa (carbidopa, Levodopa)
Tablet, Carbidopa And Levodopa (sinemet), Carbidopa And Levodopa Extended -release Tablets (25mg), Carbidopa And Levodopa Extended-release Tablets, Carbidopa
And Levodopa Orally Disintegrating Tablets, Carbidopa And Levodopa Tablets Usp, Carbidopa And Levodopa Tablets Usp, 25 Mg/100 Mg (purepac), Carbidopa And
Levodopa Tablets Usp, 25mg/250mg (purepac) (carbidopa An, Carbidopa And Levodopa Tablets, Usp, 25 Mg/100mg (purepac), Carbidopa And Levodopa Usp, 25 Mg/250
Mg (purepac), Carbidopa Levidopa, Carbidopa Levo, Carbidopa Plus Levodopa (carbidopa Plus Levodopa), Carbidopa Plus Levodopa (carbidopa Plus Levodopa)
Unknown, Carbidopa W Levodopa, Carbidopa W/ Levodopa, Carbidopa W/ Levodopa (carbidopa), Carbidopa W/ Levodopa (sinemet), Carbidopa W/carbidopa Anhydrous
W/levodopa, Carbidopa W/levodopa, Carbidopa W/levodopa (carbidopa, Levodopa), Carbidopa W/levodopa (carbidopa), Carbidopa W/levodopa (carbidopa, Levodopa(,
Carbidopa W/levodopa (carbidopa, Levodopa), Carbidopa W/levodopa (carbidopa, Levodopa), 25/100 Mg, Carbidopa W/levodopa (con.), Carbidopa W/levodopa
(levodopa, Carbidopa), Carbidopa W/levodopa (unknown), Carbidopa W/levodopa), Carbidopa With Levodopa, Carbidopa(carbidopa), Carbidopa, Levodopa (carbidopa,
Levodopa), Carbidopa- Levo, Carbidopa-l-dopa, Carbidopa-lev, Carbidopa-levadopa, Carbidopa-levidopa, Carbidopa-levidopa (sinemet), Carbidopa-levo, Carbidopa-levo
Cr-50, Carbidopa-levo Er, Carbidopa-levodopa, Carbidopa-levodopa (carbidopa), Carbidopa-levodopa Er, Carbidopa-levodopa Extended Release, Carbidopa-levodopa
www.AdverseEvents.com
Sustained Release, Carbidopa.levo 50/200, Carbidopa/ Levodopa Extended Release, Carbidopa/ Levodopa Immediate Release, Carbidopa/l-dopa, Carbidopa/ldopa,
Carbidopa/lev0d0pa, Carbidopa/levadopa, Carbidopa/levadopa (carbidopa/levadopa), Carbidopa/levadopa 25/100 Purepac/actavis, Carbidopa/levidopa, Carbidopa/levo,
Carbidopa/levo/sinemet, Carbidopa/levodo, Carbidopa/levodopa, Carbidopa/levodopa (carbidopa), Carbidopa/levodopa (carbidopa) Tablets, Carbidopa/levodopa
(carbidopa, Levodopa), Carbidopa/levodopa (carbidopa, Levodopa) Tablet, Carbidopa/levodopa (con.), Carbidopa/levodopa (not Specified), Carbidopa/levodopa (sinemet),
Carbidopa/levodopa 100mg/400mg, Carbidopa/levodopa 25-100 Mg. Caraco/aetna, Carbidopa/levodopa 25/100 Acta, Carbidopa/levodopa 25/100 Actavis Pharm.,
Carbidopa/levodopa 25/100 Extended Release, Carbidopa/levodopa 25/100 Mg, Carbidopa/levodopa 25/25, Carbidopa/levodopa Cr, Carbidopa/levodopa Er,
Carbidopa/levodopa Er (carbidopa, Levodopa), Carbidopa/levodopa Er 50/200, Carbidopa/levodopa Er 50/200 Apotex, Carbidopa/levodopa Sa 50/200mg,
Carbidopa/levodopa Sr, Carbidopa/levodopa Tablets Usp (ngx)(carbidopa, Levodopa) Tablet, Carbidopa/levodopa(25mg/100mg Qid, 06/30 ),
Carbidopa/levodopa(62.5mg/day), Carbidopa/levodopa(carbidopa), Carbidopa/levodpa 25/100, Carbidopa/melevodopa Hydrochloride, Carbidopal Evodopa (carbidopa,
Levodopa), Carbidopal/levo, Carbidope W/levodopa (carbidopa, Levodopa), Carbidope/levodopa, Carbilev, Carbilev (carbidopa, Levodopa) Unknown, Carbilev(levodopa,
Carbidopa) Unknown, Carbiodopa 25/levodopa, Carbiodopa-levodopa, Carbiodpa/levodopa, Carbo Levodopa, Carbo-levodopa, Carbo-levodopa Er, Carbo/levodopa,
Carbo/levodopa Cr, Carbodopa 25/levodopa, Caridopa/levodopa, Carpidopa/levodopa, Carvidopa/levodopa (carbidopa), Co-careldopa (carbidopa, Levodopa), Co-careldopa
(carbidopa/levodopa), Co-careldopa (sinemet), Co-careldopa (sinemet) (carbidopa, Levodopa), Co-carelodopa (sinemet), Dopadura (sinemet), Dopadura C (sinemet),
Dopadura C 100/25 Mg, Dopadura C Retard, Endo Levodopa/carbidopa, Generic Parcopa 25/100, Generic Sinemet 50/200c, Half Sinemet Cr, Isicom (carbidopa,
Levodopa), Isicom (sinemet), Isicom 100 (sinemet), Isiscom (sinemet), Kardopal (levodopa, Carbidopa), L-dopa+carbidopa, L-dopa/carbidopa, Lebocar, Lebocar
(carbidopa, Levodopa), Lebocar (levodopa, Carbidopa) Tablet, Lebocar (levodopa, Carbidopa, Carbidopa, Levodopa, Carbidopa, Levodopa, Lebocar (sinemet), Lebocar
100/25 (carbidopa , Levodopa), Lecodopa/carbidopa (sinemet), Lecomp Retard (sinemet), Leprinton, Leprinton (levodopa, Carbidopa), Leprinton (lev0d0pa, Carbidopa),
Lev. Comp Ret (sinemet), Levadopa/carbidop 25/250 Mg Info With Caremark, Levo-carbidopa, Levobeta, Levobeta (ta), Levobeta C, Levocarb-gry (sinemet /et/) (ta),
Levocomp, Levocomp (levocomp Ret) (not Specified), Levocomp (levodopa Comp C) (not Specified), Levocomp (ngx), Levocomp (sinemet), Levocomp 100, Levocomp
100 Ret, Levocomp Ret 200 (sinemet), Levocomp Ret. 200 (sinemet), Levodopa (levodopa), Levodopa (levodopa, Carbidopa), Levodopa / Carbidopa Hydrate, Levodopa
100/25 (levodopa, Carbidopa), Levodopa And Carbidopa, Levodopa And Carbidopa (sinemet), Levodopa And Carbidopa (sinement), Levodopa And Carbidopa (sinemet),
Levodopa Carbid, Levodopa Carbidopa Intestinal Gel (levodopa, Carbidopa), Levodopa Comp/levodopa, Carbidopa, Levodopa W/carbidopa, Levodopa+carbidopa (ngx),
Levodopa+carbidopa (ngx) (carbidopa, Levodopa), Levodopa+carbidopa (ngx) (carbidopa, Levodopa) 100mg/25mg, Levodopa+carbidopa (ngx)(carbidopa, Levodopa)
Unknown, 250/25mg, Levodopa, Carbidopa (carbidopa, Levodopa), Levodopa, Carbidopa (neo Dopaston), Levodopa, Carsidopa (carsidopa, Levodopa), Levodopacabidopa (carbidopa, Levodopa), Levodopa-carbidopa, Levodopa-carbidopa (carbidopa, Levodopa), Levodopa-carbidopa (carbidopa, Levodopa), Levodopa-carbidopa
(cabidopa, Levodopa), Levodopa-carbidopa (carbidopa 12.5mg And Levodopa 50mg), Levodopa-carbidopa (carbidopa 25mg And Levodopa 100mg), Levodopa-carbidopa
(carbidopa, Levodopa), Levodopa-carbidopa (carbidopa, Levodopa) Tablet, 100/25, Levodopa-carbidopa (carbidopa/levodopa), Levodopa-carbidopa (controlled-release),
Levodopa-carbidopa (levodopa), Levodopa-carbidopa (levodopa, Carbidopa), Levodopa-carbidopa (levodopra, Carbidopa), Levodopa-carbidopa (ngx) (carbidopa
Levodopa) Unknown, 25/100 Mg, Levodopa-carbidopa (sinemet) Tablets, Levodopa-carbidopa 100/25mg, Tablets (carbidopa, Levodopa), Levodopa-carbidopa 200/50mg,
Tablets (carbidopa, Levodopa), Levodopa-carbidopa Cr, Levodopa-carbidopa Intestinal Gel, Levodopa-carbidopa Intestinal Gel (levodopa, Carbidopa), Levodopa-carbidopa
Ir, Levodopa-carbidopa Unknown, Levodopa-carbidopa(tablet), Levodopa-carbipopa, Levodopa-caribidopa 200/50mg, Tablets (carbidopa, Levodopa), Levodopacaribodopa (caribodopa, Levodopa), Levodopa/carabidopa, Levodopa/carb (sinemet), Levodopa/carbidopa, Levodopa/carbidopa (carbidopa, Levodopa),
Levodopa/carbidopa (con.), Levodopa/carbidopa (levodopa Carbidopa Sandoz 100/25) (not Specified), Levodopa/carbidopa (levodopa/carbidopa) (not Specified),
Levodopa/carbidopa (not Specified), Levodopa/carbidopa Hydrate, Levodopa/carbidopa Levodopa/carbidopa (sinemet), Levodopa/carbidopa Retadiert, Levodopa/carbidopa
Unretadiert, Levodopa/carbiodopa Hydrate, Levodopa/carbodoa 50/200, Levodopa/carbodopa, Levodopa/carbodopa 25/100, Levodopa/cardidopa, Levodopa0carbidopa,
Lovodopa/carbidopa, Menesit, Menesit (carbidopa, Levodopa), Menesit (), Menesit (carbidopa, Levodopa), Menesit (carbidopa, Levodopa) Per Oral Nos, Menesit
(menesit), Menesit (sinemet /net), Menesit (sinemet /net/) (ta), Menesit (sinemet) (ta), Nacom, Nacom Msd, Nacom (nacom ), Nacom (carbidopa), Nacom (carbidopa,
Levodopa), Nacom (nacom), Nacom - Slow Release, Nacom - Slow Release (carbidopa, Levodopa), Nacom 100, Nacom 100 Retard, Nacom 200, Nacom Depot (sinemet),
Nacom Ret, Nacom Retard, Nacom Retard 200 (sinemet), Nacom Retard(sinemet) (carbidopa, Levodopa), Nacom ^dupont Pharma^, Nacom ^dupont Pharma^ (carbidopa,
Levodopa), Nacom ^msd^, Nacom ^msd^ (carbidopa, Levodopa), Nacom- Slow Release, Nacom-slow Release, Nacom-slow Release (carbidopa, Levodopa), Neo
Dopaston, Neo Dopaston (carbidopa), Neo Dopaston (carbidopa) Formulation Unknown, Neo Dopaston (carbidopa, Levodopa), Neo-dopaston, Neo-dopaston (carbidopa,
Levodopa), Neodopaston, Neodopaston (carbidola, Levodopa), Neodopaston (levodopa), Neodopaston (sinemet), Neodopaston (ta), Neopaston (levodopa/carbidopa),
Parcoba, Parcopa, Parcopa -tablets (carbdopa,levodopa), Parcopa (carbidopa/levodopa) 125 Mg, Parcopa (levodopa-carbidopa) (tablet), Parcopa (sinemet), Parcopa 10/100,
Parcopa-tablets-dose Uknown (carbidopa, Levodopa), Parcopa-tablets-dose-unknown, Parkiston, Pioglitazone Levodopa, Carbidopa (sinemet), Senemet (levodopa,
Carbidopa), Simemet, Simenet 25/250, Sinamet, Sinata, Sinemat, Sinement, Sinement (carbidopa, Levodopa), Sinemet, Sinemet /net/, Sinemet /net/(carbidopa, Levodopa),
Sinemet (sinemet) (carbidopa, Levodopa), Sinemet Half Cr (half Sinemet Cr) (co-careldopa), Sinemet (cabidopa, Levodopa), Sinemet (carbidipa/levodopa), Sinemet
(carbidopa), Sinemet (carbidopa, Levodopa0, Sinemet (carbidopa-levodopa) (carbidopa-levodopa), Sinemet (carbidopa/levodopa Controlled Release), Sinemet (carbidopal,
Levodopa), Sinemet (carbodopa / Levodopa) 50/200mg Same As Above, Sinemet (con.), Sinemet (contin), Sinemet (generic) 25-100 Tid, Sinemet (levodopa), Sinemet
(levodopa, Carbidopa) (levodopa, Carbidopa), Sinemet (levodopa, Carbidopa) (tablets), Sinemet (marbidopa, Levodopa), Sinemet (nr), Sinemet (sinemet) (carbidopa,
Levodopa), Sinemet (sinemet) (not Specified), Sinemet (sinemet) (tablets), Sinemet (sinemet) (tablets) (sinemet), Sinemet (sinemet) Tablets, Sinemet (sinemet/net), Sinemet
(sunemet), Sinemet (unknown), Sinemet - Slow Release (carbidopa/levodopa), Sinemet /net/, Sinemet /net/ (carbidopa, Levodopa), Sinemet /net/(carbidopa, Levodopa),
Sinemet 10/100 (sinemet), Sinemet 100-125, Sinemet 100/100, Sinemet 100/25, Sinemet 12.5/50 (sinemet) (sinemet), Sinemet 125, Sinemet 25/100 (sinemet) (carbidopa,
Levodopa), Sinemet 25/100 (sinemet) (sinemet), Sinemet 25/100cr, Sinemet 25/250 (sinemet) Carbidopa, Levodopa), Sinemet 50/200 Carbidopa/levo Er Tabs Apo13250/200 Torpharm (apotex), Sinemet 62.5, Sinemet Control, Sinemet Controlled Release, Sinemet Cr, Sinemet Cr (cinemet) (carbidopa, Levodopa), Sinemet Cr (sinemet),
Sinemet Cr (sinemet) (carbidopa, Levodopa), Sinemet Cr (sinemet) Tablet, Sinemet Cr 200/50, Sinemet Cr 25/100mg (sinemet), Sinemet Ct, Sinemet Depot, Sinemet Depot
(sinemet), Sinemet Er, Sinemet Er Carbidopa/levo Er Tabs Apo132- 50/200, Sinemet Ir, Sinemet Levadopa, Sinemet Lp, Sinemet Lp (carbidopa/levodopa Long Release),
Sinemet Lp (carbidopa, Levodopa) (25 Milligram, Tablets) (carbidopa, L, Sinemet Lp 50/200, Sinemet Lp Tabs 25 Mg/100 Mg, Sinemet Lp Tabs 50 Mg/200 Mg, Sinemet
Mite, Sinemet Mite (carbidopa, Levodopa), Sinemet Mite (sinemet /net/) (nr), Sinemet Mite - Slow Release (carbidopa, Levodopa), Sinemet Plus (sinemet) (carbidopa,
Levodopa), Sinemet Plus (sinemet) (levodopa, Carbidopa), Sinemet Reg, Sinemet Sa, Sinemet Sr (sinemet), Sinemet Time Release, Sinemet-cr (carbidoma, Levodopa),
Sinemet-cr (sinemet /net/), Sinemet-cr (sinemet), Sinemet-cr (tablet), Sinemet-plus (sinemet Plus (co-careldopa)) (not Specified), Sinemet/comtan, Sinemit 25/100,
Sinemmet, Sinemt, Sinemt 110, Sinenet, Sinimed, Siniment, Sinimet, Snemet (sinemet), Somemet-cr (carbidopa, Levodopa), Synamet
Stalevo
Other names: Carbidopa/levodopa/entacapone
FDA Listed Names (76):
(levldopa/carbidopa/entacapon) 100mg/25mg/200mg, Tablets, Carbidopa And Entacapone And Levodopa, Carbidopa W/entacapone W/levodopa, Carbidopa
W/entacapone/levodopa, Carbidopa W/levodopa W/entacapone, Carbidopa, Levodopa + Entacapone, Carbidopa, Levodopa And Entacapone, Carbidopa, Stalevo
(levadopa), Carbidopa,entacapone,levodopa, Carbidopa/entacapone/levodopa, Carbidopa/entacapone/levodopa (carbidopa, , Entacapone, Levodopa),
Carbidopa/entacapone/levodopa (carbidopa, Entacapone, Levodopa), Carbidopa/entacapone/levodopa Carbidopa, Entacapone, Levodopa), Carbidopa/levodopa/entacapone,
Entacapone, Carbidopa, Levodopa, Entacapone-levodopa-carbidopa, Entacapone-levodopa-carbidopa E-l-c+, Levodopa + Carbidopa + Entacapone, Levodopa - Carbidopawww.AdverseEvents.com
entacapone, Levodopa And Carbidopa And Entacapone, Levodopa, Carbidopa, Entacapone, Levodopa, Carbidopa, Entacapone (stalevo), Levodopa-carbidopa-entacapone
(levodopa, Carbidopa, Entacapone), Levodopa/carbidopa/entacapone, Staleva, Stalevo, Stalevo /usa/, Stalevo (carbidopa, Entacapone, Levodopa, Stalevo (carbidopa,
Entacapone, Levodopa), Stalevo (levodopa/carbidopa), Stalevo ((stalevo) (carbidopa, Entacapone, Levdopa), Stalevo (carbidopa), Stalevo (carbidopa, Entacapone), Stalevo
(carbidopa, Entacapone, Levodopa), Stalevo (carbidopa, Levodopa And Entacapone), Stalevo (carbidopa, Levodopa, Entacapone) (carbidopa, Levodopa, Entaca, Stalevo
(carbidopa/entacapone/levodopa), Stalevo (entacapone, Carbidopa), Stalevo (levodopa, Carbidopa, Entacapone), Stalevo (levodopa, Carbidopa, Entecapone), Stalevo
(levodopa, Carsidopa, Entacapone), Stalevo (levodopoa, Carbidopa, Entacapone), Stalevo (stalevo, Stalevo (stalevo), Stalevo (stalevo) (not Specified), Stalevo (stalevo)
(nr), Stalevo (tablet) (levodopa, Carbidopa, Entacapone), Stalevo (tablet) (levodopa, Carsidopa, Entacapone), Stalevo (tablet) (levodora, Carbidopa, Entacapone), Stalevo
(tablets), Stalevo (unknown) (levodopa, Carbidopa, Entacapone), Stalevo 100, Stalevo 100 (carbidopa, Levodopa), Stalevo 100 (stalevo), Stalevo 150, Stalevo 200 (stalevo),
Stalevo 50, Stalevo 50 -carbidopa, Stalevo 75, Stalevo 75 (stalevo), Stalevo Tablets, Stalevo Vs Carbidopa/levodopa, Stalevo(carbidopa, Levodopa, Entacapone)(carbidopa,
Levodopa, Entacapo, Stalevo(entacapone, Levodopa, Carbidopa) Tablet, Stalevo/usa/(carbidopa, Entacapone, Levodopa), Stalevol, Stalveo, Stalvevo, Stavelo (levodopa,
Carbidopa, Entacapone), Stavelo (levodopa, Carbidopa, Entacapone), Stavelo (carbidopa, Entacapone, Levodopa), Stavelo (levodopa, Carbidopa, Entacapone), Stavelo
(stalevo), Stavelo 100 Mg, Stelevo, ^stelivo^
Symmetrel
Other names: Amantadine
FDA Listed Names (160):
(amantadine), Amanatadine (amantadine /00055901/), Amanatdine, Amanatedine, Amandatin, Amandatine, Amandine, Amanitadine, Amantadin, Amantadin (amantadin),
Amantadin (amantadine Hydrochloride) (nr), Amantadin (amantadine Hydrochloride) Unknown, Amantadin (non-bi Drug), Amantadin /00055901/, Amantadin 100 Mg,
Amantadin Al, Amantadina, Amantadine, Amantadine /00055901/, Amantadine (amantadine /00055901/), Amantadine (amantadine /00055901/), Amantadine /00055901/,
Amantadine (100 Milligram Tablets), Amantadine (amanpadine /00055901/), Amantadine (amantadine, Amantadine (amantadine /00055901/), Amantadine (amantadine ),
Amantadine (amantadine / 00055901/), Amantadine (amantadine /00055901/), Amantadine (amantadine /0055901/), Amantadine (amantadine 00055901/), Amantadine
(amantadine), Amantadine (amantadine) (amantadine Hydrochloride), Amantadine (amantadine) (amantadine), Amantadine (amantadine) 200 Mg; Unknown; Bid 100 Mg;
Unknown; Qd, Amantadine (amantadine) Unknown, Amantadine (amantadine/ 00055901/), Amantadine (amantadine/00055901), Amantadine (amantadine/00055901/),
Amantadine (amantadine0, Amantadine (amantandine), Amantadine (amatadine), Amantadine (con.), Amantadine (ngx), Amantadine (ngx) (amantadine) Tablet, 100mg,
Amantadine (ngx) (amantadine) Unknown, Amantadine /00055901/, Amantadine /00055902/ (amantadine Hydrochloride), Amantadine 100 Mg, Amantadine 100mg 2x A
Day, Amantadine 100mg, Tablets (amantadine), Amantadine 200mg, Tablets (amantadine), Amantadine 50mg/5ml, Amantadine And Preparations, Amantadine Capsules,
100 Mg, (usl), Amantadine Dulfate, Amantadine Endo, Amantadine Hcl, Amantadine Hcl Caps, Amantadine Hcl Capsules Usp, Amantadine Hcl Capsules Usp
(ngx)(amantine) Capsule, Amantadine Hydrochlloride (amantadine Hydrochloride), Amantadine Hydrochloride, Amantadine Hydrochloride (symmetrel), Amantadine
Hydrochloride Tablets, Amantadine Hyrochloride 50mg, Amantadine Or Placebo (blinded Study Drug), Amantadine Plus Lithium 100mg And 300mg Unknown,
Amantadine Sulfate, Amantadine Sulfate (pk-merz), Amantadine Sulfate 100mg, Tablets (amantadine Sulfate), Amantadine Symmetrel, Amantadine Upsher-smith,
Amantadine, Manufacturer Unk., Amantadine-sulfate (amantadine Sulfate), Amantadine-sulfate 9amantadine Sulfate), Amantan, Amantan (amantadine Hydrochloride),
Amantan (amantadine) (amantadine), Amantandine, Amantandine (amantadine /00055901/), Amantazine, Amantdine, Amantidine, Amantidine (con.), Amantidine
Hemisulphate, Amazolon, Amazolon (amantadine Hydrochloride), Amazolon (amantadine Hydrochloride)c, Amntadine 100mg, Tablets (amantadine), Anantadine, Atarin,
Atarin (amantadine Hydrochloride), Blinded Amantadine, Manatadine, Mantadan, Mantadan (amantadine Hydrochloride), Mantadix, Mantadix (amantadine
Hydrochloride), Mantadix (amantadine Hydrochloride,), Mantadix (amantadine Hydrochloride), Mantadix (amantadine Hydrochloride), Mantadix (amantadine), Mantadix
(amantadine) 100 Mg Bms, Mantadix (con.), Mantadix (same As Nda 18-101) 100 Mg, Mantadix Capsules, Mantadix Capsules Lot No:, Mantidam, Mantidam (amantadine
Hydrochloride), Mantidam (mantadan (amantadine Hydrochloride)), Mantidam (mantadan) (amantadine Hydrochloride), Mantidan, Mantidan (amantadine Hydrochloride),
Mantidan (amantadine /00055901/), Mantidan (amantadine Hydrochloride), Mantidan (amantadine) (amantadine0, Mantidan [mantadan] (amantadine Hydrochloride),
Mantidan(amantadine), Matadix (amantadine Hydrochloride), Pk Merz, Pk Merz (amantadine) (amantadine Sulfate), Pk Merz 100, Pk-merz, Pk-merz /00055903/, Pk-merz
/00055903/, Pk-merz /00055903/, Pk-merz /00055902/, Pk-merz /00055903/, Pk-merz /00055903/ (pk Merz) (not Specified), Pk-merz /gfr/(amantadine Sulfate), Pk-merz
/grf/ (amantadine Sulfate), Pk-merz Infusions, Symmeterel (amantadine Hydrochloride), Symmetral, Symmetral (amantadine Hydrochloride), Symmetrel, Symmetrel /net/,
Symmetrel (amanatadine Hydrochloride), Symmetrel (amandadine Hydrochloride) Tablet, Symmetrel (amantadien Hydrchloride), Symmetrel (amantadine Hdyrochloride),
Symmetrel (amantadine Hyderochloride) Tablet, Symmetrel (amantadine Hydrchloride), Symmetrel (amantadine Hydrochloride Sodium), Symmetrel (amantadine
Hydrochloride) (ta), Symmetrel (amantadine Hydrochloride) (tablets), Symmetrel (amantadine Hydrochloride) Per Oral Nos, Symmetrel (amantadine Hydrochloride0,
Symmetrel (ammantadine Hydrochloride), Symmetrel (con.), Symmetrel /net/ (amantadine Hydrochloride), Symmetrel /net/ (amantadine Hydrochloride) Tablet,
Symmetrel/net/(amantadine Hydrochloride), Symmetril, Symmetryl, Syrimetrel (amantadine), Topharmin, Topharmin (amantadine Hydrochloride), Viregyt-k (amantadine
Hydrochloride)
Tasmar
Other names: Tolcapone
FDA Listed Names (9):
Tasmar, Tasmar (tolcapone), Tasmar (tolcapone) (dr), Tasmar (tolcapone) (tolcapone), Tazmar, Tolcapone, Tolcapone ( Tolcapone), Tolcapone (tolcapone), Tolcapone
(tolcapone) (tolcapone)
Zelapar
Other names: Zydis Selegiline, Xilopar (Germany), Otrasel (France)
FDA Listed Names (98):
Amboneural (selegiline Hydrochloride), Deprenyl, Deprenyl /00500001/, Deprenyl /00500001/(selegiline), Deprenyl 5, Deprenyl 5 (selegiline), Egibren (selegiline),
Eldeprul, Eldepryl, Eldepryl (selegiline Hyrochloride), Eldepryl (selegiline Hydrochloride) (ka), Eldepryl (selegiline Hydrochloride) (selegiline Hydrochloride), Eldepryl
www.AdverseEvents.com
(selegiline Hydrohcloride), Elderpryl (selegiline Hydrochloride), Elderpryl (selegiline), Fp, Fp (ta), Fp (selegiline Hydrochloride), Fp (selegiline Hydrochloride) (ta), Fp
(selegiline), Fp (selegilne Hydrochloride), Fp (serlegiline Hydrochloride), Fp (ta), Fp Tablet (selegiline Hydrochloride), Fp Tablet 2.5, Jumax (selegiline), Jumex, Jumex
(selegiline), Jumex (selegiline), Jumex (selegiline) (tablets), Jumexal, Kinabide, Movergan, Movergan (selegiline Hydrochloride), Niar, Novo-selegiline (selegiline
Hydrochloride), Plurimen, Plurimen (selegiline Hydrochloride), Plurimen (selegiline Hydrochloride) (5 Mg), Procythol (selegiline), Segiline (selegiline), Selegam, Selegam
(selegiline Hydrochloride), Selegam (selegline Hydrochloride), Selegelin, Selegeline, Selegeline (1.25mg/day), Selegeline (selegeline), Selegeline (selegiline), Selegeline
Hcl, Selegeline Hydrochloride, Selegeline Hydrochloride (selegeline Hydrochloride), Selegilane, Selegilene, Selegilin, Selegilin Nm (selegiline Hydrochloride) Tablet,
Selegilin Stada, Selegiline, Selegiline (selegiline), Selegiline (selegiline), Selegiline (nr), Selegiline (poultice Or Patch), Selegiline (selegelin), Selegiline (selegiline),
Selegiline (selegiline) (selegiline), Selegiline (selegiline) Tablet, Selegiline (unknown), Selegiline 5mg, Tablets (selegiline), Selegiline Hcl, Selegiline Hcl Sandoz,
Selegiline Hcl Tabs, Selegiline Hydochloride (selegiline Hydrochloride), Selegiline Hydrochloride, Selegiline Hydrochloride (selegiline Hydrochloride), Selegiline
Hydrochloride (selegiline Hydrochloride), Selegiline Hydrochloride (eldepryl), Selegiline Hydrochloride (selegiline Hydrochloride), Selegiline Hydrochloride (selegiline
Hydrchloride), Selegiline Hydrochloride (selegiline Hydrochloride), Selegiline Hydrochloride (silegiline Hydrochloride), Selegiline Hydrochloride(selegiline
Hydrochloride), Selegiline Hydrochoride, Selegiline Hyrochloride (selegiline Hydrochloride), Selegiline Odt (zelapar), Selegiline Patch (selegiline Hydrochloride),
Selegilne, Selegilne Hydrochloride, Selegine, Selegine (selegiline Hydrochloride), Selegine 5mg Apotex, Seleginile Hydrochloride, Selgin (selegiline Hydrochloride),
Seligiline, Silegiline (selegiline), Zelapar, Zelapar (selegiline Hydrochloride), Zelepar, Zelopar
www.AdverseEvents.com
Appendix B
Adverse Event Search Terms Used to Query the FDA AERS Database
Gambling-Related
gambling, pathological gambling
All ICD-Related
anorexia and bulimia syndrome, binge eating, bulimia nervosa, compulsions, compulsive hoarding, compulsive lip biting, compulsive sexual behaviour, compulsive
shopping, delusion of grandeur, delusional disorder, erotomanic type, delusional disorder, grandiose type, delusional disorder, jealous type, delusional disorder, mixed type,
delusional disorder, persecutory type, delusional disorder, somatic type, delusional disorder, unspecified type, delusional perception, delusions, mixed, dermatillomania,
disinhibition, disturbance in sexual arousal, eating disorder symptom, eating disorder, economic problem, erotomanic delusion, excessive exercise, excessive masturbation,
excessive sexual fantasies, food craving, food hoarding, gambling, high risk sexual behaviour, hyperphagia, hypersexuality, hypersomnia-bulimia syndrome, impulsecontrol disorder, impulsive behaviour, jealous delusion, kleptomania, libido disorder, libido increased, nail picking, obsessive rumination, obsessive thoughts, obsessivecompulsive disorder, obsessive-compulsive personality disorder, paraphilia, pathological gambling, persecutory delusion, repetitive speech, sexual abuse, sexual activity
increased, sexual dysfunction, sexual offence, sexually inappropriate behaviour, shoplifting, somatic delusion, theft, tongue biting, transvestism
www.AdverseEvents.com