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FIRST NEWS BULLETIN 1-888-800-DRUG (3784) www.pharmacyfirst.com The Leading National Network of Retail Community Pharmacies • August 29, 2006 ESPRIT PHARMA SANCTURA® MARKET SHARE PROGRAM BEGINS SEPTEMBER 1ST Pharmacy First is pleased to announce it has entered into an agreement with Esprit Pharma and contracted Sanctura® to be the preferred product in the overactive bladder (OAB) category. Beginning September 1,2006 as part of the Rx$hare program,members will have an opportunity to earn rebates from 2% to 7% off WAC by growing network market share over the national average. Sanctura® is indicated in overactive bladder with symptoms of urge urinary incontinence,urgency, and frequency. Side effects include: Dry mouth,dryness of eyes,blurred vision,upset stomach,heachache,constipation,difficulty urinating,drowsiness,or dizziness. Preferred Product Preferred NDC Non-Preferred Products Sanctura 15456-0980-04 Enablex Ditropan XL 65473-0980-04 Vesicare Detrol LA Oxytrol Detrol Sanctura® (trospium chloride) facts and talking points: • The only quaternary amine indicated for treating overactive bladder (OAB) • Unique chemical structure offers several important benefits: - In Phase 3 clinical studies,Sanctura showed significant improvements in symptoms of OAB as early as day 1 - Unlike most prescription therapies,Sanctura is minimally metabolized by CYP450 enzyme system - No known metabolic drug interactions • Sanctura is the safe choice when CNS risks are a concern • Low incidence of CNS side effects - Less than 1% of the patients reported blurred vision - No effect on daytime sleepiness For more information and frequently asked questions,please refer to www.Sanctura.com To maximize program earnings, dispense Sanctura whenever possible as a preferred brand for your pharmacy and inform your pharmacists and technicians that Sanctura is now on the Pharmacy First preferred product list. Helping patients using Sanctura to remain compliant with authorized refills will also work to maximize program performance and your subsequent earnings. For information about this or any other Pharmacy First program, please call 1-888- 800-DRUG (3784) weekdays during business hours (Eastern Time) and a network representative will be happy to answer your questions.