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50 25 N H EK H eL aS3 0 G M 12 87 8 Percentage overlap with HTE DHS 75 Background cell types Supplementary Figure 1. Cell-type specificity of DNase I hypersensitive sites (DHS) in HTE cells. The genomic overlap between DHS in HTE and NHEK cells measured as the percentage of HTE DHS that overlap with each of the individual background cell types. Also shown are GM12878 and Hela-S3 for comparison.