Download ROSE CRYSTA-70(Rose Petal Extract)

Anti-Metabolic Syndrome/blood glucose level control
ROSE CRYSTA series
ROSE CRYSTA-70
Ｒ
(Rose Petal Extract)
ROSE CRYSTA-70 (Concentrated Rose Polyphenol) is the natural product
containing polyphenol concentrated from rose petal extract.
Features of ROSE CRYSTA-70
● ROSE CRYSTA-70 is the powdered extract by extracting from natural rose petals, and concentrating,
and spray-drying.
● ROSE CRYSTA-70 contains more than 70% rose petal polyphenol.
● ROSE CRYSTA-70 can control blood glucose level after eating.
● ROSE CRYSTA-70 has more efficient activity in anti-oxidation than it in vitamin C.
About Metabolic Syndrome
Metabolic Syndrome is the syndrome from metabolic disorder not only in Japan, but whole world, especially in developed
countries. First, visceral fat accumulates, and the second, one of abnormal sugar metabolism, high blood pressure, and
high triglyceride/low HDL cholesterol is confirmed, you will be called "preliminary", two or all, you are in metabolic Syndrome.
In metabolic syndrome, it is certain that circulatory organs become worse and diseases such as arteriosclerosis, further
it will cause critical accidents like apoplectic accident and myocardial infarction. A half of male and one fifth of female
persons is metabolic syndrome or preliminary, in more than 40 years old Japanese (Ministry of Health, Labour and Welfare,
Japan, 2004).
Primary and basic method of escape from metabolic syndrome is changing your lifestyle. It contains to change dietary
habits, to do sports or practice, to manage stress... Changing dietary life is the most important. No eating must be adverse
effect in diet, and changing quality of dietary foods is efficient. Lower calories, lower fat (especially animal fat), and more
vegetables are necessary. ROSE POLYPHENOL relieves that exertion. ROSE POLYPHENOL can control blood glucose
level, and it keeps blood glucose level low after eating. It also derives to keep insulin level low, to suppress producing fats
from sugars. It is reported that ROSE POLYPHENOL inhibits lipase activity that degraded triglyceride to glycerol and
fatty acids. This means that ROSE POLYPHENOL suppress absorption of fat and producing fat. As a result,
ROSE POLYPHENOL/ROSE
CRYSTA-70 is effective for improvement of your lifestyle.
ROSE CRYSTA series
ROSE CRYSTA-CO
Product name
Generic name
Ingredients label
Standard Doses
Standard Package
Use-by date
Appearance
Odor
Polyphenol contents
Heavy metals (as Pb)
Arsenic (as As2O3)
Number of viable cells
for suppress sunburn, keep
moisture, supple skin, anti-wrinkle
Coriform group
Mold/Yeast
Usage
ROSE CRYSTA-70
(Food ingredient)
for prevention from diabetes and metabolic syndrome.
ROSE CRYSTA
(Food ingredient)
for suppress anaphylaxis (type I) ]
allergy,keep skin white, beauty.
(Cosmetics material)
R
ROSE CRYSTA-70
ROSE PETAL EXTRACT
ROSE PETAL EXTRACT
100 mg/day
1kg/alminum bag, 6 bags in a carton box
2 years from manufacturing date(incasebagiskeptclosed)
Red purple to Red brown powder
Characteristic Odor
not less than 70%
Not more than 20ppm
Not more than 2ppm
Not more than 3000cfu/g
Negative(-)
Not more than 300cfu/g
Tablet, capsule, gum, candy etc...
Manufacturing
Process
Raw material/Mixing
->
Extraction
->
Concentration
->
Purification
->
Spray dry
->
Packaging
ROSE CRYSTA series
Anti-Metabolic Syndrome/blood glucose level control
RO SE CRYSTA-70
Experimental Data
α-Glucosidase Inhibition
Polyphenol concentration
IC50(50% inhibition conc.)
Inhibition (%) no addition=0%
[Method]
Samples are incubated for 5 minutes at 37 ℃ with p-nitrophenol-α-Dglucopyranoside (NPD) 2.5 mM (concentration at test). After incubation,
α-glucosidase (from yeast) was added to 0.005 U/ml at the reaction concentration.
After incubation for 15 minutes at 37 ℃, equal volume of 0.2 M sodium carbonate
solution was added to stop the reactions. α-glucosidase activities were calculated
from the absorbance of each solution at 400 nm.
[Results and Discussion]
The inhibition activities against α-glucosidase are getting stronger by higher
concentration of polyphenol in rose petal extracts. Especially ROSE CRYSTA-70
shows the most strongly inhibition activity.
Α-glucosidase is the enzyme to degrade maltose to glucose. Then the producing
and increasing of glucose is slow. As a result, glucose absorption will be calm,
and ascending of blood glucose level will be mild.
Sample concentration (ppm)
Blood Glucose Level Control
Time (minute)
Control
Test (560 mg)
Blood Glucose (mg/dL)
Control
Test (100 mg)
Blood Glucose (mg/dL)
[Method]
7 and 5 healthy persons are tested with 560 mg and
100 mg dose, respectively. Subjects had nothing
except water or pale tea after 9 P.M. the days before
their tests, and also they did not have their breakfasts.
In each test, blood glucose level was
measured (0 min.) before eating 200 g of rice.
Each subject additionally eats 560 mg or 100 mg of
ROSE CRYSTA-70 as a test group, nothing else as
a control group. Blood glucose levels were measured
at 30 min., 60 min., and 120 min. after finishing eating rice.
Time (minute)
Anti-Oxidation Activity
DPPH-radical elimination activities of ROSE CRYSTA, ROSE CRYSTA-70,
and popular anti-oxidant Vitamin C and E were measured.
ROSE CRYSTA showed twice or three times stronger activity than Vitamin E,
furthermore ROSE CRYSTA-70 have much stronger activity than Vitamin C.
DPPH radical elimination activity(%) Vitamin C = 100%
[Results and Discussion]
The blood glucose levels at 30 min. were different in both 100 mg and 560mg test groups, comparing with that of control groups(* : p<0.05, + : p<0.1).
These results indicate that ROSE CRYSTA-70 can prevent against diabetes and metabolic syndrome by preventing rapid glucose level ascending and
following ascending insulin level. Insulin is known to stimulate producing fatty acid, and keeping insulin level low have possibility to reduce fat and to lose weight.
DPPH radical elimination activity
Vitamin C Vitamin E ROSE CRYSTA
ROSE CRYSTA-70