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Meconium Aspiration Syndrome RT 256 Meconium  Material that collects in the intestine of the fetus  Intestinal tract secretions  Amniotic fluid  Pulmonary fetal fluid  Intrauterine debris  Forms the first stools of the newborn  Thick and sticky, highly viscous  Green to black in color Aspiration of Meconium 1. Physical presence in the airways 2. Chemical pneumonitis 3. Hypoxia induced pulmonary arterial vasoconstriction and vasospasm Physical presence in the airways leads to: • • • • Upper airway obstruction Migration past glottis Penetration into smaller airways Ball-valve effect – alveolar rupture  Acute inflammatory reaction Chemical Pneumonitis  Edema  Excessive bronchial secretions  Alveolar consolidation  Promotes the growth of bacteria  Decreases pulmonary surfactant production  Hypoxia induced pulmonary Hypoxemia arterial vasoconstriction and vasospasm  Shunts blood right to left through the ductous arterious and foramen ovale  Intrapulmonary shunting  Pulmonary hypoperfusion Etiology  10% of births  High risk for MAS include  Post-term  Small for gestational age  Breech presentation  Mother with toxemia, hypertension, or obesity  Cause of meconium passage, consistency, and timing Meconium passage 1. A PHYSIOLOGIC MATURATION EVENT 2. RESPONSE TO ACUTE HYPOXIC EVENTS OCCURRING LATE IN PREGNANCY 3. RESPONSE TO CHRONIC INTRAUTERINE HYPOXIA Presentation  Amniotic fluid examined  Meconium staining of skin, nails, umbilical cord  Manifestations of Respiratory Distress:  Barrel chest  Breath sounds – rhonchi, crackles, wheezing  Retractions  Cyanosis  Increased respiratory rate  Increased heart rate Management  PREVENTION!  Suctioning during delivery (not current NRP guideline)  Current NRP guidelines for meconium:  Vigorous vs Not Vigorous Strong respiratory efforts  Good muscle tone  Heart rate >100beats/min    Intubate and suction with ETT Do NOT ventilate until all meconium is cleared  Oxygen Therapy  Support ventilation as required  Medications