Download Dra. Sigal Ben-Yehuda.

Dra. Sigal Ben-Yehuda.
Nationality: Israeli
Current appointment
Associate Professor
Department of Microbiology and Molecular Genetics
Institute for Medical Research, Israel-Canada (IMRIC)
Faculty of Medicine The Hebrew University of Jerusalem
Phone no: 972-2-6758600
Fax: 972-2-6758311
E-mail: [email protected]
Recent Appointments
01/12/2003-1/10/2008: Senior Lecturer (Department of Microbiology and Molecular
Genetics)
1/10/2008-Now: Associate Professor (Department of Microbiology and Molecular
Genetics)
Academic Qualifications
01/2000- 10/2003: Post-Doctoral training at Harvard University, Department of
Molecular and Cellular Biology,
Advisor: Prof. Richard Losick.
Subject: Sporulation in Bacillus subtilis.
11/95-12/99: Ph.D. studies at Tel-Aviv University, Department of Molecular
Microbiology and Biotechnology.
Advisor: Dr. Martin Kupiec.
Thesis subject: "Cell cycle control through pre-mRNA splicing in the yeast
Saccharomyces cerevisiae".
10/93-10/95: M.Sc. studies at Tel-Aviv University, Department of Molecular
Microbiology and Biotechnology.
Advisor: Dr. Martin Kupiec.
Thesis subject: "Characterization of the CDC40 gene in the yeast Saccharomyces
cerevisiae".
10/90-10/93: B.Sc. in Biology, Tel-Aviv University.
Academic Awards
2011: Annual Meeting of the German Society for Hygiene and Microbiology-DGHM
lecture
2011: The Sir Zelman Cowen Prize for discovery in medical research
2011: The ISM (Israel society for microbiology) Shilo Award
2007: ERC (European Research Council)-Independent Researcher Starting Grant
2007: The Hebrew University President’s Award (Ben-Porat) for excellence in
research
2006: The EMBO Young Investigator Award (EMBO YIP)
2006: The Hebrew University Faculty of Medicine Dean’s Matzner Award for
excellence in research
2004: The Human Frontier Science Program-career development award
2000: The Human Frontier Science Program Fellowship for postdoctoral training
2000: The Fulbright fellowship for postdoctoral training
1997: The Trotzky scholarship for outstanding Ph.D. students
1997: The British council scholarship for undertaking research at Edinburgh
University
1994: The Dean scholarship for outstanding M.Sc. students
1992: The Dean scholarship for outstanding B.Sc. students
List of Relevant Publications
Ben-Yehuda, S., and Losick, R. (2002). Asymmetric cell division in B. subtilis involves
a spiral-like intermediate of the cytokinetic protein FtsZ. Cell 109: 257-266.
Ben-Yehuda, S., Rudner, D.Z., and Losick, R. (2003). RacA, a bacterial protein that
anchors chromosomes to the cell poles. Science 299: 532-536.
Eichenberger, P., Jensen, S. T., Conlon, E. M., van Ooij, C., Silvaggi, J., GonzalezPastor, J. E., Fujita, M., Ben-Yehuda, S., Stragier, P., Liu, J. S., and Losick, R. (2003).
The sigmaE regulon and the identification of additional sporulation genes in Bacillus
subtilis. J Mol Biol. 327: 945-972.
Ben-Yehuda, S., Rudner, D. Z., and Losick, R. (2003). Assembly of the SpoIIIE DNA
translocase depends on chromosome trapping in Bacillus subtilis. Current Biol. 13:
2196-2200.
Ben-Yehuda, S., Fujita, M., Liu, X.S., Gorbatyuk, B., Skoko, D., Yan, J., Marko, J.F.,
Liu J.S., Eichenberger, P., Rudner, D.Z., and Losick, R. (2005). Defining a
centromere-Like element in Bacillus subtilis by identifying the Binding Sites for the
Chromosome-Anchoring Protein RacA. Mol. Cell, 18:773-82.
Carniol, K., Ben-Yehuda, S., King, N., and Losick R. (2005). Genetic Dissection of
the Sporulation Protein SpoIIE and Its Role in Asymmetric Division in Bacillus subtilis.
J. Bacteriol. 187:3511-3520.
Bejerano-Sagie, M., Oppenheimer-Shaanan, Y., Berlatzky, I., Rouvinski, A., and BenYehuda, S. (2006). A checkpoint protein that scans the chromosome for damage at
the start of sporulation in Bacillus subtilis. Cell, 125: 679-690.
Hazan, R and Ben-Yehuda, S. (2006). Resolving Chromosome Segregation in
Bacteria. J. Mol. Biol. and Biotech, 11: 126-139 (A review article).
Garti-Levi S., Hazan, R., Kain J., Fujita M., and Ben-Yehuda, S. (2008). The FtsEX
ABC transporter directs cellular differentiation in Bacillus subtilis. Mol Microbiol.
69:1018-1028.
Burton, KA., Nollmann, BM., Ptacin, M., Bustamante, C., Ben-Yehuda, S., and
Rudner, DZ. (2008). SpoIIIE strips proteins off the DNA during chromosome
translocation. Genes Dev. 22:1786-1795.
Berlatzky, I., Rouvinski, A., and Ben-Yehuda, S. (2008). Spatial organization of a
replicating bacterial chromosome. Proc Natl Acad Sci U S A. 105:14136-14140.
Meyerovich, M., Mamou, G., and Ben-Yehuda, S. (2010). Visualizing high error levels
during gene expression in living bacterial cells. Proc Natl Acad Sci U S A. 107:1154311548.
Elbaz, M., and Ben-Yehuda, S. (2010). The metabolic enzyme ManA reveals a link
between cell wall integrity and chromosome morphology. PLoS Genet. 16;6(9). pii:
e1001119.
Dubey, P. G., and Ben-Yehuda, S. (2011). Intercellular Nanotubes Mediate Bacterial
Communication. Cell, 144(4):590-600.
Nevo-Dinur, K., Nussbaum-Shochat, A., Ben-Yehuda, S., and Amster-Choder, O.
(2011) Translation-independent localization of mRNA in E. coli. Science, 331:10811084.
Oppenheimer-Shaanan, Y., Wexselblatt, E., Katzhendler, J., Yavin, E., and BenYehuda, S.. (2011). c-di-AMP Reports DNA Integrity during Sporulation in B. subtilis.
EMBO Report, 12(6):594-601.
Segev, E., Smith, Y., and Ben-Yehuda, S. RNA dynamics in aging bacterial spores.
(2012). Cell, 148(1-2):139-149.