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r*PHYSORDE*r + + HALIFAX HEALTH 303 N. Clyde Morris Blvd., Daytona Beach, FL 32114 1041 Dunlawton Ave., Port Orange, FL 32127 "X" IN BOX FOR STAT MED PHYSICIAN’S ORDERS Patient Name Adm. Date Date of Birth MR # Dr. Age Visit # DILTIAZEM (CARDIZEM) MEDICATION (NDOSCARDIZ) ALLERGIES: Page 1 of 1 HIGH RISK / DO NOT USE ABBREVIATIONS: U, IU, MS, MSO4, MgSO4, QD, QOD. ALWAYS WRITE OUT INTENDED MEANING AND USE METRIC. DO NOT USE A ZERO AFTER A DECIMAL; ALWAYS USE A ZERO BEFORE A DECIMAL. DATE TIME CK’D (✔) X CHECK BOX TO INITIATE ORDER ❑ Patient Status: (select only one) ❑ Admit to Inpatient. I certify that inpatient services are necessary. ❑ Place in Observation ❑ Case Management Protocol Attending Physician is________________________________________________________ 1. X ❑ Bolus 0.25 mg/kg undiluted Cardizem IV over 2 minutes 2. X ❑ If response is inadequate after 15 minutes: Rebolus with 0.35 mg/kg Cardizem IV X 3. ❑ Start infusion: 5 mg/hour (5 ml/hour) for 24 hours May titrate to 15 mg/hour to maintain the desired heart rate and continue for up to 24 hours Requires physician order to titrate OFF 4. X ❑ IV infusion of Diltiazem (Cardizem) in 0.9% Normal Saline for a final concentration of 1 mg/ml 5. Cardizem Guidelines: 1.) Contraindicated in patients with hypotension, sick sinus syndrome, second and complete AV block, and in patients with acute myocardial infarction and pulmonary edema 2.) Continuous ECG and blood pressure monitoring 3.) Multiple drug incompatibilities include: (do not give through the same IV line) Furosemide (Lasix) Phenytoin Insulin Methylprednisolone Diazepam Sodium Bicarbonate 4.) Most common drug interactions: • Beta−blockers − decreased heart rate, cardiac index and prolonged PR interval • Digoxin − increased digoxin plasma concentrations • Cyclosporin − increased cyclosporin plasma concentrations • Amiodarone − increased diltiazem plasma concentrations 5.) Monitoring Therapy: • Vital Signs: blood pressure, pulse, and respirations should be documented a minimum of every 15 minutes x 4 after initial bolus, then every 4 hours during continuous infusion • Posting and interpretation of rhythm strip before administration and with any significant rhythm and/or hemodynamic change 6.) If the patient has symptomatic hypotension and/or displays signs of changes, STOP the infusion and notify physician 7.) Conversion from IV to oral: 3 mg/hour = 120 mg/day 5 mg/hour = 180 mg/day 7 mg/hour = 240 mg/day 11 mg/hour = 360 mg/day Physician Signature:__________________________________________ Dictation #:__________________ PHYSICIANS: PLEASE REMEMBER TO USE YOUR DICTATION NUMBER WITH YOUR SIGNATURE. PHYS ORDER ALL ORDERS TO PHARMACY HMC − 1564 − 2/10