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The most important and frequent mode of transmission of nosocomial
infections is by direct contact.
LEARNING OBJECTIVE [ edit ]
Differentiate between the various types of transmission: airborne, common vehicle, vector
borne, direct and indirect contact transmission
KEY POINTS [ edit ]
Contact transmission is divided into two subgroups: directcontact transmission and indirect
contact transmission.
Directcontact transmission involves a direct body surfacetobody surface contact and physical
transfer ofmicroorganisms.
Indirectcontact transmission involves contact of asusceptible host with a contaminated
intermediate object, usually inanimate.
TERMS [ edit ]
transmission
Transmission is the passing of a communicable disease from an infected host individual or group
to a conspecific individual or group, regardless of whether the other individual was previously
infected.
microorganisms
A microorganism or microbe is a microscopic organism that comprises either a single cell
(unicellular), cell clusters, or multicellular relatively complex organisms.
susceptible
likely to be affected by something; here, sensitive to growth inhibition by an antimicrobial drug.
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The drugresistantGramnegativebacteria,
for the most part, threaten only
hospitalized patients
whose immune systems are weak. They
can survive for a long time on surfaces in
the hospital and they enter the body
through wounds, catheters, and
ventilators.
The most important and frequent mode of
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transmission ofnosocomial infections is
by direct contact.
Transmission occurs when droplets containing microbesfrom the infected person are
propelled a short distance through the air and deposited on the host's body; droplets are
generated from the source person mainly by coughing, sneezing, and talking, and during the
performance of certain procedures, such as bronchoscopy.
Dissemination can be either airborne droplet nuclei (smallparticle residue {5 µm or smaller
in size} of evaporated droplets containing microorganisms that remain suspended in the air
for long periods of time) or dust particles containing the infectious agent. Microorganisms
carried in this manner can be dispersed widely by air currents and may become inhaled by a
susceptible host within the same room or over a longer distance from the source patient,
depending on environmental factors; therefore, special airhandling and ventilation are
required to prevent airborne transmission. Microorganisms transmitted by airborne
transmission include Legionella, Mycobacterium tuberculosis and the rubeola and varicella
viruses.
Common vehicle transmission applies to microorganisms transmitted to the host by
contaminated items, such as food, water, medications, devices, and equipment .
Crosstransmission
Contaminated surfaces increase crosstransmission.
Vector borne transmission occurs when vectors such as mosquitoes, flies, rats, and other
vermin transmit microorganisms.
Contact transmission is divided into two subgroups: directcontact transmission and
indirectcontact transmission.
Directcontact transmission involves a direct body surfacetobody surface contact and
physical transfer of microorganisms between a susceptible host and an infected or colonized
person, such as when a person turns a patient, gives a patient a bath, or performs other
patientcare activities that require direct personal contact. Directcontact transmission can
also occur between two patients, with one serving as the source of the infectious
microorganisms and the other as a susceptible host.
Indirectcontact transmission involves contact of a susceptible host with a contaminated
intermediate object, usually inanimate, such as contaminated instruments, needles, or
dressings, or contaminated gloves that are not changed between patients. In addition, the
improper use of saline flush syringes, vials, and bags has been implicated in disease
transmission in the US, even when healthcare workers had access to gloves, disposable
needles, intravenous devices, and flushes.