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Transcript 
URINE FORMATION
I.
Glomerular Filtration
A. Occurs in Bowman’s capsule (fenestrae)
1. glomerular capillaries highly permeable
2. small molecular weight substances leave
capillary and go into the capsule
a. water
b. glucose
c. ions (Na+, K+, Ca2+, Mg2+, Cl-, HCO3-)
d. urea (nitrogen containing)
B.
Blood remaining in efferent vessel is highly
viscous (containing rbc’s and large proteins).
II. Tubular reabsorption
A. Substances needed by body transported from
proximal tubule back into peritubular capillaries
B. Osmosis- water
C. Passive transport- urea (approx. ½ back into
bloodstream).
D. Active transport- glucose, amino acids, vitamins,
ions, escecially Na+
some reabsoption also occurs in distal tubule
III. Tubular Secretion
A. Substances moved from plasma of peritubular
capillaries into distal tubule.
B. Substances secreted
1. Organic substances (penicillin, creatinine,
histamine) only in the proximal tubule.
2. Hydrogen ions*
3. Potassium ions*
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