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Department of Pharmaceutical Sciences Faculty Research Interests Faculty Dr. Carvalho, Paulo Research Interests Synthesis of enzymatic inhibitors against tropical diseases; Natural Product Chemistry; Development of analytical methods for the identification and quantification of drugs and their metabolites in biological fluids Dr. Coker, Adeola Biophysical analysis, formulation development, and characterization of protein therapeutics using design of experiments Dr. Gottlieb, Helmut Determine the CNS sites and mechanisms involved in the opioid mediated effects in water and electrolyte balance Dr. LaGrange, Lilia Characterize Role of BK Channels in Smooth Muscle Function; Scholarship of teaching and learning Dr. Mosley, Anita Drug solubilization, nanoparticle technology, dosage from design and drug delivery Dr. Oliveira, Marcos Understanding the mechanism through which polyamines regulate biofilm in bacteria; Development of novel antibacterial agents targeting polyamines Dr. Ramsinghani, Sushma Design, synthesis, and evaluation of inhibitors of Poly(ADPribose) glycohydrolase for cancer therapy Dr. Sharpe, Amanda Examination of Neurocircuitry regulating energy homeostasis, use of illicit drugs and food intake using behavioral, molecular and imaging techniques Dr. Sikazwe, Donald Discovery Medicinal Chemistry for neurodegenerative disease (Alzheimer’s) applications Dr. Smith, Helen Investigate the relationships between genetic polymorphisms and the risks for disease development, drug efficacy and/or toxicity; Investigate the impact of pharmacy on the environment. Dr. Yendapally, Raghunandan Design and synthesis of novel small molecule antimicrobial agents