Survey
* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project
Download Metabolism
Document related concepts
no text concepts found
Transcript
Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning Metabolism • Photosynthesis • Fuel • Metabolism Copyright 2005 Wadsworth Group, a division of Thomson Learning Chemical Reactions Copyright 2005 Wadsworth Group, a division of Thomson Learning Adenosine Triphosphate Copyright 2005 Wadsworth Group, a division of Thomson Learning Chemical Reactions • Coupled reactions Copyright 2005 Wadsworth Group, a division of Thomson Learning A Typical Cell Copyright 2005 Wadsworth Group, a division of Thomson Learning Chemical Reactions Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Chemical Reactions • Helpers in reactions –Enzymes •Cofactors –Coenzymes Copyright 2005 Wadsworth Group, a division of Thomson Learning Nutrients for Energy Copyright 2005 Wadsworth Group, a division of Thomson Learning Nutrients for Energy • Glycolysis • Pyruvate acetyl CoA • TCA cycle • Electron transport chain Copyright 2005 Wadsworth Group, a division of Thomson Learning Glycolysis: Glucose-toPyruvate Copyright 2005 Wadsworth Group, a division of Thomson Learning Glucose • The fate of pyruvate –Anaerobic vs. aerobic pathways Copyright 2005 Wadsworth Group, a division of Thomson Learning Glucose • The fate of pyruvate –Anaerobic •Pyruvate-to-lactic acid –Cori cycle Copyright 2005 Wadsworth Group, a division of Thomson Learning Pyruvate-to-Lactic Acid (Anaerobic) Copyright 2005 Wadsworth Group, a division of Thomson Learning Glucose • The fate of pyruvate –Aerobic •Pyruvate-to-acetyl CoA Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Pyruvateto-Acetyl CoA (Aerobic) The Paths of Pyruvate and Acetyl CoA Copyright 2005 Wadsworth Group, a division of Thomson Learning Glucose yields energy Copyright 2005 Wadsworth Group, a division of Thomson Learning Glycerol & Fatty Acids • Glycerol-to-pyruvate Copyright 2005 Wadsworth Group, a division of Thomson Learning Glycerol & Fatty Acids • Fatty acids-to-acetyl CoA Copyright 2005 Wadsworth Group, a division of Thomson Learning Fatty acids-to-acetyl CoA, cont’d Copyright 2005 Wadsworth Group, a division of Thomson Learning Fats Enter the Energy Pathway Copyright 2005 Wadsworth Group, a division of Thomson Learning Glycerol & Fatty Acids • Fatty acids cannot be used to synthesize glucose Copyright 2005 Wadsworth Group, a division of Thomson Learning Amino Acids • Amino acids-to-acetyl CoA Copyright 2005 Wadsworth Group, a division of Thomson Learning Amino Acids • Amino acids-to-glucose Copyright 2005 Wadsworth Group, a division of Thomson Learning Amino Acids • Deamination – Keto acid – Ammonia Copyright 2005 Wadsworth Group, a division of Thomson Learning Amino Acids • Transamination Copyright 2005 Wadsworth Group, a division of Thomson Learning Amino Acids • • Ammoniato-urea Copyright 2005 Wadsworth Group, a division of Thomson Learning Urea excretion via the kidneys Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning The Final Steps • The TCA cycle –oxaloacetate Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning The TCA Cycle The Final Steps • The electron transport chain Copyright 2005 Wadsworth Group, a division of Thomson Learning Electron Transport Chain and ATP Synthesis Copyright 2005 Wadsworth Group, a division of Thomson Learning The Final Steps • The kcalories-per-gram secret revealed Copyright 2005 Wadsworth Group, a division of Thomson Learning The Central Pathways of Energy Metabolism Economics of Feasting • Excess protein • Excess carbohydrate • Excess fat Copyright 2005 Wadsworth Group, a division of Thomson Learning Economics of Feasting Copyright 2005 Wadsworth Group, a division of Thomson Learning Economics of Fasting Copyright 2005 Wadsworth Group, a division of Thomson Learning Economics of Fasting • Glucose needed for the brain • Protein meets glucose needs Copyright 2005 Wadsworth Group, a division of Thomson Learning Economics of Fasting • Shift to ketosis Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Economics of Fasting • Suppression of appetite • Slowing of metabolism • Symptoms of starvation Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol and Nutrition Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol and Nutrition • Alcohol is a drug Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol in Beverages • Moderation –A drink –Proof Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol in Beverages Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol in the Body • Alcohol dehydrogenase • Alcohol: Males vs. females Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol in the Body Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol Arrives in the Liver • Acetaldehyde • Alcohol abuse • NAD Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol Disrupts the Liver • Fatty liver Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol Disrupts the Liver • Fibrosis • Cirrhosis Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol Disrupts the Liver • MEOS = microsomal ethanoloxidizing system Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol Arrives in the Brain • Narcotic effects • Effect on ADH Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning kCal in Alcoholic Beverages & Mixers, cont’d Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol’s effects on the Brain Alcohol & Malnutrition • Nutrient displacement • Interference with nutrient metabolism Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol & Malnutrition • Alcoholism • Wernicke-Korsakoff syndrome Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol’s Short-Term Effects • Suicide • Homicide • Accidents Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol’s Short-Term Effects • Assault • Sexual assault Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol’s Short-Term Effects Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol’s Long-Term Effects • Alcohol and pregnancy • Heavy alcohol consumption Copyright 2005 Wadsworth Group, a division of Thomson Learning Alcohol’s Long-Term Effects Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Personal Strategies • Social aspects • Consumption strategy • Myths Copyright 2005 Wadsworth Group, a division of Thomson Learning
Related documents