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Summary of the gross and microscopic changes in cardiac hypertrophy. (A) Gross photo of heart with hypertrophy caused by aortic stenosis. The wall of
the left ventricle is thick and the chamber is not dilated. The left ventricle is on the lower right in this apical four-chamber view of the heart. (B) Altered
cardiac configuration in left ventricular hypertrophy without and with dilation, viewed in transverse heart sections. Compared with a normal heart (center of
this panel), a pressure overloaded heart, caused for example by aortic valve stenosis (left in [B]), has increased mass and a thick left ventricular wall,
whereas a volume overloaded heart, caused for example by mitral valve regurgitation, is both hypertrophied and dilated (right), having increased mass
with a near normal or diminished wall thickness. (C) Photomicrograph of normal myocardium. (D) Photomicrograph of hypertrophied myocardium, showing
Source: Chapter 5. Cardiovascular Pathology, Cardiac Surgery in the Adult, 4e
large cells with enlarged. ([B] Reproduced with permission from Edwards WD: Cardiac anatomy and examination of cardiac specimens, in Emmanouilides
Citation: Cohn
LH. Cardiac
the Adult,
4e; 2012
Available
at: http://mhmedical.com/
Accessed:
May 14,
2017 the Fetus and Young
GC, Riemenschneider
TA, Allen
HD, et Surgery
al [eds]:inMoss
and Adams
Heart
Disease
in Infants, Children, and
Adolescents:
Including
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Adults, 5th ed. Philadelphia, Williams & Wilkins, 1995; p 86. [C and D] Reproduced with permission from Schoen FJ, Mitchell RN: The heart, in Kumar V,
Fausto N, Abbas A, et al [eds]: Robbins/Cotran Pathologic Basis of Disease, 8th ed. Philadelphia, WB Saunders, 2010; pp 529-687.)