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Table S3. The complete list of GO terms associated to the 228 significant genes in
common between the FRDA children and FRDA adults.
Biological Process Term
Biopolymer modification
Protein modification
Ubiquitin cycle
Biopolymer metabolism
Cellular physiological process
Primary metabolism
Protein ubiquitination
Cellular metabolism
Cell cycle
Modification-dependent protein catabolism
Ubiquitin-dependent protein catabolism
RNA splicing
Nucleobase, nucleoside, nucleotide and nucleic acid metabolism
Cellular macromolecule metabolism
Metabolism
Cellular protein metabolism
Macromolecule metabolism
Regulation of biological process
Cellular process
Proteolysis during cellular protein catabolism
Cellular protein catabolism
RNA splicing, via transesterification reactions with bulged
adenosine as nucleophile
RNA splicing, via transesterification reactions
Nuclear mRNA splicing, via spliceosome
Regulation of progression through cell cycle
Regulation of cell cycle
Gene#
%
p-Value
36
34
16
49
130
95
8
97
15
6
6
6
49
46
101
45
61
50
143
6
6
16.98%
16.04%
7.55%
23.11%
61.32%
44.81%
3.77%
45.75%
7.08%
2.83%
2.83%
2.83%
23.11%
21.70%
47.64%
21.23%
28.77%
23.58%
67.45%
2.83%
2.83%
6.98E-05
2.11E-04
2.82E-04
2.93E-04
0.001292853
0.010047576
0.013332587
0.013816613
0.016291689
0.018942198
0.018942198
0.022615388
0.024651005
0.025380996
0.029117486
0.030274442
0.034670416
0.039158158
0.04095028
0.042232244
0.043122072
5
2.36%
0.043414678
5
5
10
10
2.36%
2.36%
4.72%
4.72%
0.043414678
0.043414678
0.053480914
0.054060984
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