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Download Human disease caused by parasites
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Human disease caused by parasites • Predominant intestinal parasites Intestinal entry and maturation • Intestinal entry, disease elsewhere Larval stage leaves the gut • Skin entry, gut manifestations Mature stage enters the gut • Skin entry, disease elsewhere Dissemination Failure to complete life cycle Predominant intestinal parasites Intestinal worms: ascaris lumbricoides trichuris trichiuria taenia saginata enterobius vermicularis Intestinal protozoans giardia lamblia cryptosporidium parvum entamoeba histolytica Human disease caused by parasites • Intestinal entry, disease elsewhere acquired toxoplasmosis hydatid disease (echinococcus) cysticercosis (taenia solium) visceral larva migrans (Toxocara canis) trichinosis (trichinella spiralis) • Skin entry, intestinal manifestations Hookworm Strongyloides Schistosoma mansoni Human disease caused by parasites • Skin entry, localized disease Leishmaniasis Filariasis • Skin entry, disease by dissemination Malaria Trypanosomiasis Schistosomiasis Intestinal Parasites : mode of infection Ingestion of cysts, Entry of larvae or oocysts or ova oncospheres Site of adult stage or disease Cryptosporidium Giardia Amoebiasis Intestine Toxoplasmosis Visceral Trichinella Ingested larva migrans Disseminated Ascaris Trichuris Enterobius Intestine Hookworm Strongyloides through skin Symptoms Parasite Abdominal pain and distension Giardia Cryptosporidium Amoebiasis Ascaris, hookworm, taenia Diarrhoea +/- malabsorption Giardia Cryptosporidium Strongyloides Diarrhoea with blood loss Amoebiasis Trichuris Hookworm Tenesmus, prolapsed rectum Trichuris Intestinal parasites: Symptoms Symptom Mechanism Parasite Anaemia Blood loss Amoebiasis Hookworm Trichuris S mansoni Malabsorption Giardia Diphyllobothrium Malnutrition Heavy infestation Intestinal Parasites : Symptoms Symptom Mechanism Parasites Skin rash Papulovesicular Creeping eruption Peri-anal rash and pruritus Hookworm Strongyloides Enterobius Respiratory symptoms Pulmonary migration Ascaris Hookworm Strongyloides Toxocara Intestinal Parasites : Surgical Symptoms Symptom Mechanism Parasite Intestinal obstruction Worm bolus Ascaris Appendicitis Obstruction Ascaris Jaundice, biliary colic Biliary obstruction Ascaris Prolapsed rectum Tenesmus, weight loss Trichuris Intestinal perforation Transmural necrosis and peritonitis Amoebiasis
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