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Transcript
Necrobacillosis
Def :
Infectious disease of animals caused by
Fusobacterium necroforum (Spheropherous
necrophorum)
• Characterized by necrotizing lesions in the
alimentary tract ,liver and respiratory system.

Different conditions produced by the
organism in different animals
In Cattle :





liver necrosis
Ulcerative rumenitis
Ulcerative &necrotizing stomatitis and
enteritis
Necrosis of tail , teat ,limbs and feet
Foot rot (pododermatitis )
Necrotic Stomatitis
Foot rot
Necrobacillosis
In calves




Calf diphtheria
Bronchopneumonia, purulent or necrotic
pneumonia and pleurisy
Acute catarrhal, ulcerative or necrotic enteritis
Calf usually dies after 4-5 days due to
pneumonia and toxemia
Necrobacillosis
In sheep


Foot rot
Lip and leg ulceration
Necrobacillosis
In horse :




Severe necrotizing disease of feet
Gangrenous dermatitis ch’ch’ by sharply
demarcated necrosis.
It is associated with fistulus withers
ulcerative enteritis in foals
Route of infection
Secondary invasion following mucosal
damage or viral Ds.
( oral wound, trauma, eruption of teeth)
(predisposing causes)

The organism invade the damaged
mucosa and produce Endo&Exo toxins
leading to Necrosis.
Spread of infection within the
infected animal :

Aspiration of necrotic material

Ingestion of necrotic material

Emboli
lung
Gangrenous Pneumonia.
Oesophagus
Intestine
Stomach
necrotic enteritis
Circulation
Necrotic
lesions in different organs.
Spread of infection within the
infected animal :


Hepatic necrobacillosis observed in
lambs and calves following
omphalophlebitis or as a
complication after ruminitis in
cattle.
Infection of vagina and uterus after
parturition as contamination after
inflammatory genital diseases.
Large well demarcated yellowish gray
dry areas of necrosis surrounded by a
hyperaemic zone on the tongue, gum,
palate ,cheeks and pharynx.
 Necrotic areas project above the
mucosal surface
Sloughs
Deep ulcer
 Diphtheric membrane of
fibrinonecrotic exudate on the buccal
mucosa , pharynx and larynx
 Toe abscess and cellulitis may occur in
sheep

Structureless area of necrosis
surrounded by hyperaemic zone and
leucocytes,
later by thick capsule of granulation
tissue
Hepatic necrobacillosis
Hepatic necrobacillosis
Calf diphtheria
Ch’ch’ by pseudomembrane formation
(fibrinonecrotic exudate on the top of deep
ulcers )