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(A) The cerebellar cortex is organized into three layers and contains five types of neurons. A vertical section of a single cerebellar folium, in both
longitudinal and transverse planes, illustrates the general organization of the cerebellar cortex. A glomerulus is a clear space where the bulbous terminal of
a mossy fiber makes synaptic contact with Golgi and granule cells. (B) Bundles of parallel fibers, called beams, run transversely and excite the dendrites of
Purkinje cells flanking the parallel fiber beam. (C) Synaptic organization of the basic cerebellar circuit module. Mossy and climbing fibers convey output
from the cerebellum via a main excitatory loop through the deep nuclei. This loop is modulated by an inhibitory side-loop passing through the cerebellar
cortex. This figure shows the excitatory (+) and inhibitory (−) connections among the cell types. Parts B & C show the geometry of the divergence and
Source: Chapter 41. Physiology and Pathophysiology of the Cerebellum, and Rehabilitation Strategies after Cerebellar Injury, Movement
convergence of these basic connections. (Reproduced with permission from Ghez C and Thach WT. The cerebellum. In Kandel ER, Schwartz JH, and
Disorders, 3e
Jessell TM (eds). Principles of Neural Science, 4th ed. New York: McGraw-Hill, Inc., 2000, pp. 836–837 [Figs 41–4, 41–5, and 41–6])
Citation: Watts RL, Standaert DG, Obeso JA. Movement Disorders, 3e; 2012 Available at: http://mhmedical.com/ Accessed: May 13, 2017
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