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Genetic Variations with Populations 11.1 & 11.2 Genetic variation – the quantity of different genes within a species. As a general rule, the more genetic variation, the better… Genetic variation is stored in a populations gene-pool – the combined alleles (genes) of all individuals within a population. Allele frequency – a measure of how common an allele is within a population. Recall that an allele IS a gene; it is simply one of many forms of THAT gene. mutation– a random change in the DNA of a gene. Recall that a gene is a specific sequence of DNA that makes a protein. If genes make proteins, and proteins determine traits, what COULD possibly happen if a mutation occurs? Normal distribution (bell-curve): type of distribution in which the count is highest near the mean value and lower at the extremes. What the heck does that mean, Mr. Allen?! Microevolution: the observable change in the allele frequencies of a population over time. Natural Selection can lead to microevolution. Directional selection: a type of selection that favors phenotypes at one extreme of a traits range. Example: long necks become more common. Natural selection can favor different alleles on the bell-curve distribution. Stabilizing selection: a type of selection that favors the intermediate phenotype. Example: medium blue becomes more common. Natural selection can favor different alleles on the bell-curve distribution. Disruptive selection: a type of selection that favors extreme phenotypes. Example: very tall and very short people become more common.