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Memory Check 6: Meningitis and Encephalitis Site Infectious Agents Lesion Manifestations CSF MemChk.Neuro.6.MdP Bacterial Meningitis Pia mater, arachnoid, subarachnoid space, CSF, ventricles Neisseria, pneumococci, haemophilus Aseptic Meningitis Meninges Encephalitis Meninges, white and gray matter Enteroviral viruses, herpes simplex1 Meningeal vessels become hyperemic and permeable Throbbing headache, flexion of legs and thighs, stiff neck projectile vomiting, confusion Increased pressure, bacteria, elevated protein levels, decreased glucose levels, neutrophils and monocytes Similar to bacterial Arthropod-borne viruses, herpes simplex1, complications of systemic viral infection Nerve cell degeneration Mild but similar symptoms compared with bacterial meningitis Increased pressure, normal glucose levels, lymphocytes Fever, delirium, confusion, coma, seizure, cranial nerve palsies, paresis and paralysis Same as aseptic meningitis