Download Chapter 8 Chromosome Mutations: Variation in Chromosome

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

page
1
page
2
page
3
page
4
page
5
page
6
page
7
page
8
page
9
page
10
page
11
page
12
page
13
page
14
page
15
page
16
page
17
page
18
page
19
page
20
page
21
page
22
page
23
page
24
page
25
page
26
page
27
page
28
page
29
page
30
page
31
page
32
page
33
page
34
page
35
page
36
page
37
page
38
page
39
page
40
page
41
page
42
page
43
page
44
page
45
page
46
page
47
page
48
page
49
page
50
page
51
page
52
page
53
page
54
page
55
page
56
page
57
page
58
page
59
page
60
page
61
page
62
page
63
page
64
page
65
page
66
page
67
page
68
page
69
page
70
page
71
page
72
Document related concepts
no text concepts found
Transcript 
Art and Photos in PowerPoint®
Concepts of Genetics
Ninth Edition
Klug, Cummings, Spencer, Palladino
Chapter 8
Chromosome Mutations: Variation in
Chromosome Number and Arrangement
Copyright
© 2009©Pearson
Education,
Inc.
Copyright
2009 Pearson
Education,
Inc.
8.1 Specific Terminology Describes
Variations in Chromosome Number
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Table 8.1
8.1 Specific Terminology Describes
Variations in Chromosome Number
8.1.1 Variation in the Number of Chromosomes
Results from Nondisjunction
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.1
8.2 Monosomy, the Loss of a Single
Chromosome, May Have Severe
Phenotypic Effects
Partial Monosomy in Humans—
Cri-du-Chat Syndrome
46,5p-
Copyright © 2009 Pearson Education, Inc.
46,5p-
Copyright © 2009 Pearson Education, Inc.
Figure 8-2
Cri-du-Chat
Copyright © 2006 Pearson Prentice Hall, Inc.
8.3 Trisomy Involves the Addition of a
Chromosome to a Diploid Genome
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.2
A trisomy can be perpetuated
Copyright © 2009 Pearson Education, Inc.
Figure 8.3
8.3 Trisomy Involves the Addition of a
Chromosome to a Diploid Genome
8.3.1 Down Syndrome
Copyright © 2009 Pearson Education, Inc.
47,21+
Copyright © 2009 Pearson Education, Inc.
Figure 8.4
Copyright © 2009 Pearson Education, Inc.
Figure 8.5
8.3 Trisomy Involves the Addition of a
Chromosome to a Diploid Genome
8.3.2 Patau Syndrome
Copyright © 2009 Pearson Education, Inc.
47,13+
1:19,000
Copyright © 2009 Pearson Education, Inc.
Figure 8.6
8.3 Trisomy Involves the Addition of a
Chromosome to a Diploid Genome
8.3.3 Edwards Syndrome
Copyright © 2009 Pearson Education, Inc.
47,18+
1:8,000
Copyright © 2009 Pearson Education, Inc.
Figure 8.7
8.3 Trisomy Involves the Addition of a
Chromosome to a Diploid Genome
8.3.4 Viability in Human Aneuploidy
Up to 30 percent of all fertilized eggs in humans
may contain an error in chromosome number!
45,X has one of the highest incidence rates among
abortuses. Also, about 80 percent of 45,X have the
maternal X.
Copyright © 2009 Pearson Education, Inc.
8.4 Polyploidy, in Which More Than Two
Haploid Sets of Chromosomes Are
Present, Is Prevalent in Plants…
But very rare in animals or humans.
Copyright © 2009 Pearson Education, Inc.
Full report here
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.8
8.4 Polyploidy, in Which More Than Two
Haploid Sets of Chromosomes Are
Present, Is Prevalent in Plants
8.4.1 Autopolyploidy
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.9
8.4 Polyploidy, in Which More Than Two
Haploid Sets of Chromosomes Are
Present, Is Prevalent in Plants
8.4.2 Allopolyploidy
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.10
8.4 Polyploidy, in Which More Than Two
Haploid Sets of Chromosomes Are
Present, Is Prevalent in Plants
8.4.3 Endopolyploidy
Copyright © 2009 Pearson Education, Inc.
8.5 Variation Occurs in the Internal
Composition and Arrangement of
Chromosomes
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.13
Copyright © 2009 Pearson Education, Inc.
Figure 8.13a
Copyright © 2009 Pearson Education, Inc.
Figure 8.13b
Copyright © 2009 Pearson Education, Inc.
Figure 8.13c
Copyright © 2009 Pearson Education, Inc.
Figure 8.13d
Copyright © 2009 Pearson Education, Inc.
Figure 8.13e
8.6 A Deletion Is a Missing Region of a
Chromosome
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.14
Copyright © 2009 Pearson Education, Inc.
Figure 8.14a
Copyright © 2009 Pearson Education, Inc.
Figure 8.14b
Copyright © 2009 Pearson Education, Inc.
Figure 8.14c
8.6 A Deletion Is a Missing Region of a
Chromosome
8.6.1 Cri du chat Syndrome in Humans
Segmental deletion
Copyright © 2009 Pearson Education, Inc.
8.6 A Deletion Is a Missing Region of a
Chromosome
8.6.2 Drosophila Heterozygous for Deficiencies May
Exhibit Pseudodominance
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Table 8.2
8.7 A Duplication Is a Repeated Segment
of the Genetic Material
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.17
Gene Copy Number Variants
Gene Xeroxing
Science (2007) 317:1315-1317
Copyright © 2009 Pearson Education, Inc.
8.7 A Duplication Is a Repeated Segment
of the Genetic Material
8.7.1 Gene Redundancy and Amplification: Ribosomal
RNA Genes
8.7.2 The Bar-Eye Mutation in Drosophila
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.18
Copyright © 2009 Pearson Education, Inc.
Figure 8.18a
Copyright © 2009 Pearson Education, Inc.
Figure 8.18b
8.7 A Duplication Is a Repeated Segment
of the Genetic Material
8.7.3 The Role of Gene Duplication in Evolution
Copyright © 2009 Pearson Education, Inc.
8.8 Inversions Rearrange the Linear Gene
Sequence
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.19
Copyright © 2009 Pearson Education, Inc.
Figure 8.20
8.8 Inversions Rearrange the Linear Gene
Sequence
8.8.1 Consequences of Inversions during Gamete
Formation
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.21
Copyright © 2009 Pearson Education, Inc.
Figure 8.22
Copyright © 2009 Pearson Education, Inc.
Figure 8.22a
Copyright © 2009 Pearson Education, Inc.
Figure 8.22b
8.8 Inversions Rearrange the Linear Gene
Sequence
8.8.2 Position Effects of Inversions
8.8.3 Evolutionary Advantages of Inversions
Copyright © 2009 Pearson Education, Inc.
8.9 Translocations Alter the Location of
Chromosomal Segments in the
Genome
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.23a
Copyright © 2009 Pearson Education, Inc.
Figure 8.23b
Copyright © 2009 Pearson Education, Inc.
Figure 8.23c
8.9 Translocations Alter the Location of
Chromosomal Segments in the
Genome
8.9.1 Translocations in Humans: Familial Down
Syndrome
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.24
Copyright © 2009 Pearson Education, Inc.
Figure 8.24a
Copyright © 2009 Pearson Education, Inc.
Figure 8.24b
Copyright © 2009 Pearson Education, Inc.
Figure 8.24c
Copyright © 2009 Pearson Education, Inc.
Figure 8.25
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
8.10 Fragile Sites in Humans Are
Susceptible to Chromosome Breakage
8.10.1 Fragile X Syndrome (Martin–Bell Syndrome)
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 8.26
Related documents