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Pathologies of the Hormones of the Endocrine System The Hypothalamus- if the hormone is lacking or too much, the corresponding hormone will increase or decrease in levels in the blood. 1. Inhibiting Hormones a. MIF b. GHIG c. PIH 2. Releasing Hormones a. CRH b. GRH or GHRH c. TRH d. PRH e. GnRH The Glands 1. The Pituitary Gland 1. The Anterior lobe- the adenohypophysis. A. Hyposecretion- Reduced LH and FSH i. Panhypopituitarianism ii. Loack of Gonadotropin in men iii. Dwarfism in Children iv. TSH Deficiency v. ACTH Deficiency vi. Sheehan’s Syndrome B. Hypersecretion i. Gigantism / Acromegaly ii. Galactorrheah ( Lactation in men ) 2. Middle lobe of the Pituitary 3. The Posterior lobe-the neurohypophesis A. Diabetes Insipidus 2. Thyroid Gland a. Insufficient intake of iodine leads to goiter. b. Too little thyroxin = hypothyroidism ( myxedema) ( endemic Cretenism). c. Too much thyroxin = hyperthyroidism ( Graves Disease / thyrotoxicosis). 3. The Parathyroids a. hyperfunction i. excessive calcium in the blood ii. Cardiac Arrythmias iii. Kidney Stones iv. Osteoporosis 4. The Adrenal Glands a. hypofunction i. Addison’s Disease ii. Cortisol Deficiency iii. Hyperpigmentation b. hypofunction i. Thinning hair ii. Osteoporosis b. hyperfunction i. Adrenal Virulism ii.Cushing’s Syndrome iii. Hyperaldosteronism iv. Primary/Secondary Aldosteronism 5. Pineal Gland a. Hypofunction i. sleep disturbances ii. low HGH iii. decreased pituitary function 6. The Gonads a. Hypofunction i. decreased sexual characteristic 7. The Pancreas 8. The Thymus OTHER SITES THAT SECRETE HORMONES 1. Gastrointestinal Tract 2. Placenta 3. Kidneys 4. Heart 5. Most Tissues in the body 1