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Pathologies of the Hormones of the Endocrine System
The Hypothalamus- if the hormone is lacking or too much, the corresponding hormone will increase or decrease in levels in the blood.
1.
Inhibiting Hormones
a. MIF
b. GHIG
c. PIH
2.
Releasing Hormones
a. CRH
b. GRH or GHRH
c. TRH
d. PRH
e. GnRH
The Glands
1. The Pituitary Gland
1. The Anterior lobe- the adenohypophysis.
A. Hyposecretion- Reduced LH and
FSH
i. Panhypopituitarianism
ii. Loack of Gonadotropin
in men
iii. Dwarfism in Children
iv. TSH Deficiency
v. ACTH Deficiency
vi. Sheehan’s Syndrome
B. Hypersecretion
i. Gigantism / Acromegaly
ii. Galactorrheah ( Lactation in men )
2. Middle lobe of the Pituitary
3. The Posterior lobe-the neurohypophesis
A. Diabetes Insipidus
2. Thyroid Gland
a. Insufficient intake of iodine leads to goiter.
b. Too little thyroxin = hypothyroidism ( myxedema) ( endemic Cretenism).
c. Too much thyroxin = hyperthyroidism ( Graves Disease / thyrotoxicosis).
3. The Parathyroids
a. hyperfunction
i. excessive calcium in the blood
ii. Cardiac Arrythmias
iii. Kidney Stones
iv. Osteoporosis
4. The Adrenal Glands
a. hypofunction
i. Addison’s Disease
ii. Cortisol Deficiency
iii. Hyperpigmentation
b. hypofunction
i. Thinning hair
ii. Osteoporosis
b. hyperfunction
i. Adrenal Virulism
ii.Cushing’s Syndrome
iii. Hyperaldosteronism
iv. Primary/Secondary Aldosteronism
5. Pineal Gland
a. Hypofunction
i. sleep disturbances
ii. low HGH
iii. decreased pituitary function
6. The Gonads
a. Hypofunction
i. decreased sexual characteristic
7. The Pancreas
8. The Thymus
OTHER SITES THAT SECRETE HORMONES
1. Gastrointestinal Tract
2. Placenta
3. Kidneys
4. Heart
5. Most Tissues in the body
1
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