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Neurotransmitter Chart Neurotransmitter Function Acetylcholine (Ach) Excitatory: Stimulates muscle contraction; involved in memory, learning and general intellectual functioning Inhibitory: pleasurable sensations involved in movement, attention, learning, and Inhibitory: moods and emotional states Excitatory: Used for arousal in the flight/fight response, plays a role in learning and memory retrieval Inhibitory: helps to offset excitatory messages and regulate daily sleep-wake cycles Inhibitory: involved in pain perception and positive emotions Dopamine Serotonin Norepinephrine GABA (gammaaminobutyric acid) Endorphins Glutamate Excitatory: Used in memory, learning, movement Effect of Deficit Alzheimer’s Effect of Surplus Severe Muscle Spasms Agonist Drug Nicotine Antagonist Drug Curare Black Widow Spider Venom Parkinson’s Schizophrenia Drug Addiction L-dopa Cocaine Depression, mood disorders Mental disorders, especially depression Autism Prozac SSRIs Caffeine, Amphetamines Anxiety Anxiety Sleep and eating disorders Valium, Xanax, ALCOHOL Body experiences pain Body may not give adequate warning about pain, Artificial highs Too much glutamate (and too little GABA) associated with epileptic seizures Opiates Anti-psychotic drugs like Thorazine Naloxone