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24 TAKING ACTION THE CANCER CONTINUUM An overview of interventions and potential for impact: Opportunities for cancer control exist at all stages of the cancer continuum, from preventing cancer to developing and providing adequate palliative care. 1 Interventions for cancer prevention and respectively, particularly in economically control at the individual and population levels developing countries. Furthermore, transmission exist across the cancer continuum from prevention of these and some other cancer causing agents of risk factors to early detection, treatment and (e.g., Schistosoma haematobium, hepatitis C virus) palliative care. 2 Tobacco use, the cause of the can be prevented by improving hygiene and most preventable cancers worldwide, can be educating people to modify their high risk substantially reduced through increased excise behaviors. Protection from harmful sun exposure tax on cigarettes, smoke-free air laws, restrictions reduces the risk of skin cancer. Cancer-causing on promotion, and counter-advertising. Indoor occupational exposures can be prevented through and outdoor air pollution, which account for a improved workplace safety. substantial proportion of lung cancer deaths, can be reduced through use of clean stoves, cleaner and breast cancers detects the disease at an early fuels, proper ventilation, and air quality guide- stage, when the chance for survival and cure is lines and policies. 3 Vaccines against Hepatitis B virus and human papillomaviruses could reduce high. A heightened awareness of warning signs the future burden of liver and cervical cancers, cancers may also lead to detection of cancers at 2 3 Smoking cessation is beneficial at all ages, but especially before middle age. Cervical cancer deaths are preventable. PROBABILITY OF DEATH FROM LUNG CANCER BY ATTAINED AGE MALE 85+ yrs 25% Quit at age 50–59 yrs 20% “ “An ounce of prevention is worth a pound of cure.” — Benjamin Franklin 85+ yrs 20% Quit at age 40–49 yrs Quit at age < 40 yrs 15% 5,000 15% 10% 5% cancers, including cancers of the breast, colon and rectum, and testis and for many childhood 55–59 yrs 5% 80–84 yrs Bangladesh 5,000 14,000 Ethopia 7,000 120,000 Uganda India 5,000 5,000 Kenya Nigeria 10% 55–59 yrs 80–84 yrs 19,000 Pakistan 7,000 Never Smoked an early stage. 4 Effective treatment (surgery, chemothera- 25% Quit at age 60–69 yrs Regular screening for cervical, colorectal, py, and radiation) has been developed for several 30% Quit at age 70+ yrs for cancer of the oral cavity, skin, and some other NUMBER OF FUTURE DEATHS THAT COULD BE PREVENTED IN ONE YEAR IF 70% OF 9-YEAR-OLD GIRLS WERE VACCINATED FEMALE Current Smoker 30% Congo 60–64 yrs 60–64 yrs Myanmar 10,000 Tanzania cancers. For certain cancers such as testis, treatment could lead to cure even for advanced stage disease. Pain associated with cancer can be 65–69 yrs controlled by administration of analgesic drugs. Full application of these interventions globally 75–79 yrs 70–74 yrs 65–69 yrs 75–79 yrs 70–74 yrs could prevent a substantial proportion of cancer deaths worldwide. 1 A 70% price increase on tobacco along with a 10% reduction in consumption through other tobacco control measures would Interventions for cancer prevention and control at the individual and population levels exist across the cancer continuum. avoid 25 million cancer deaths by 2050. 4 Childhood cancer survival rates have doubled over the past several decades in higher-income countries but lag behind in middle- and lower-income countries. FIVE-YEAR SURVIVAL RATE FROM CHILDHOOD CANCERS 83% 80% 2005 PREVENTION TOBACCO CONTROL HEALTHY DIET PHYSICAL ACTIVITY EARLY DETECTION COLORECTAL CANCER SCREENING BREAST CANCER SCREENING CERVICAL CANCER SCREENING SUN PROTECTION VACCINATION success in numbers 47,000 breast cancer deaths worldwide could be avoided annually if physical inactivity were eliminated. TREATMENT CHEMOTHERAPY HORMONE THERAPY RADIATION SURGERY success in numbers Biennial colorectal cancer screening using the fecal occult blood test, a low-cost method, can result in a 15–20% decrease in colorectal cancer mortality. SURVEILLANCE PSYCHOSOCIAL CARE MANAGEMENT OF LONG-TERM EFFECTS success in numbers Due to advances in treatment, the five-year survival rate for testicular cancer is now greater than 90% END-OF-LIFE CARE HOSPICE CARE success in numbers There are an estimated 33 million adult cancer survivors worldwide who have been diagnosed in the past five years. 48% PALLIATION 41% the cumulative burden Cancer accounts for PAIN MANAGEMENT & PSYCHOSOCIAL CARE in countries where treatment is available. Canceratlas.cancer.org Copyright © 2014 The American Cancer Society, Inc. SURVIVORSHIP & QUALITY OF LIFE 1998–2002 1988–1989 1973–1977 40% 1990–2001 31% 1960–1964 34% of the adult palliative care needs in the world. United States HIGHER INCOME Slovenia Cuba India LOWER INCOME Canceratlas.cancer.org Copyright © 2014 The American Cancer Society, Inc.