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Molecular and cellular biology
D. Gurarie
Biochemistry
Basic components:
proteins, hydrocarbons, lipids, nucleic acids, other
Basic processes:
Metabolism: building (assembling, disassembling) intra/extra cellular
components, removal of waste products.
Energy transfer. Energy is typically stored in large molecules like ATP, or
polymers (polysaccharides, lipids, proteins)
Catabolism: break-up of polymers into monomers (monosaccharides,
fatty acids, amino acids), the excess energy being stored (ADP-> ATP)
Anabolism synthesis of polymers from monomers (requires energy
from ATP)
Signaling and cellular function/control (activation, proliferation, death)
Neural transmission
Many metabolic (and other biochemical) processes are controlled by ultraefficient catalysts – enzymes (complex proteins)
Example: ADT-ATP kinetics
Catabolism
Anabolism
ATP kinetics and structure
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