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30th Annual ResMed: RESIDENTIAL SCHOOL ON MEDICINAL CHEMISTRY AND BIOLOGY IN DRUG DISCOVERY Wyndham Hotel, Florham Park, New Jersey June 5 – June 10, 2016 ResMed 2016 - Preliminary Program Basic Principles of Medicinal Chemistry Target Identification and Validation Enzyme Inhibition Kinase Inhibitors G-Protein Coupled Receptors Drugs Affecting Ion Channels Epigenetic Targets Bioisosteres Hit-to-Lead Process in Drug Discovery Principles of Lead Optimization Drug-like Properties Fragment-Based Drug Design Chemoinformatics Molecular Modeling Structure-Based Drug Design Protein Binding Pharmacokinetics Drug Metabolism Protein-Protein Interactions Improving Drug Candidates by Design Designing Around Toxicophores Preclinical Toxicology Clinical Development Case History Presentations