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I
II
III
FOUNDATIONS
1.
2.
3.
4.
5.
6.
7.
8.
9.
TABLE OF CONTENTS
TABLE OF CONTENTS
Embryology 3
Teratogenesis5
Cell Biology: Organelles
7
Cell Biology: Cytoplasm & Cytoskeleton
10
Cell Biology: Plasma Membrane
12
Cellular Suffering and Death
16
Inflammation18
Extracellular Environment
20
Cellular Adaptations
22
NEURO
1. Brain Embryology
26
2. Nervous System Basics
28
3. Cortex and Brain Lesions
30
4. Cranial Nerves part 1
33
5. Cranial Nerves part 2
36
6. Brainstem in Cross Section
39
7. Brainstem Lesions
42
8. Limbic System and Hypothalamus
47
9. CSF and ICP
50
10. Vascular Events
52
11. Seizures54
12. Headache57
13. Brain Tumors
61
14. Sleep63
15. Anesthetics66
16. Movement 68
17. Basal Ganglia
74
18. Spinal Cord and Lesions
76
19. Brachial Plexus and Upper Extremity Nerves part 1
79
20. Brachial Plexus and Upper Extremity Nerves part 2
83
21. Lower Extremity and Skeletal Muscle
87
22. Sensation91
23. Eye93
24. Ear95
25. Delirium and Dementia
98
PHARM BASICS
1. Parasympathetic Activation
103
2. Parasympathetic Inhibition
106
3. Sympathetic Activation
108
4. Sympathetic Inhibition
110
5. Neurotransmission112
6. G Protein Second Messengers
115
7. Pharmacokinetics118
8. Pharmacodynamics123
9. Drug Metabolism
125
10. Drug Elimination
127
11. Drug Side Effects
131
12. Antidotes135
[i]
TABLE OF CONTENTS
TABLE OF CONTENTS
IV
V
VI
[ ii ]
CARDIOVASCULAR
1. Embryology139
2. Congenital Heart Defects
142
3. Cardiac Output
144
4. Heart Failure
146
5. Treatment of CHF
148
6. Edema and Shock
150
7. Cardiac Cycle
153
8. Diastolic Heart Murmurs
157
9. Systolic Heart Murmurs
159
10. Electrophysiology161
11. Antiarrhythmics163
12. Electrocardiography165
13. Arrhythmias167
14. Regulation of BP
172
15. Hypertension174
16. Antihypertensives176
17. Atherosclerosis179
18. Antianginal Therapy and Lipid-Lowering Agents
182
19. Myocardial Infarction part 1
184
20. Myocardial Infarction part 2
187
21. Cardiomyopathies and Endocarditis
189
22. Other Cardiac Pathology
191
23. Vasculitis193
24. Other Vascular Diseases
195
RHEUM & DERM
1.
2.
3.
4.
5.
6.
7.
8.
Bone Formation and Bone Tumors
Bone Disorders
Musculoskeletal Injuries
Osteoarthritis and Rheumatoid Arthritis Other Types of Arthritis
Systemic Disorders
Dermatology part 1
Dermatology part 2
REPRODUCTION
199
201
204
208
210
212
214
217
1. Reproductive Anatomy 221
2. Genital Embryology
223
3. Androgens225
4. Testicular Pathology
227
5. Penis and Prostate Pathology
229
6. Female Reproductive Cycle
232
7. Menstruation and Menopause
235
8. Vulva, Vagina and Cervix 238
9. Uterine Pathology
240
10. Ovarian Pathology 242
11. Ovarian Neoplasms
244
12. Pregnancy part 1
247
13. Pregnancy part 2
249
14. Chromosomal Disorders
251
15. Genetic Disorders: AD and Trinucleotide Repeats
253
16. Genetic Disorders: AR and X-Linked
255
17. Breast257
VII
VIII
MICRO
1. Bacterial Basics
263
2. Bacterial Toxins
265
3. Staphylococcus267
4. Streptococcus269
5. Other Gram-Positive Bacteria
271
6. Gram-Negative Bacteria part 1
273
7. Gram-Negative Bacteria part 2
275
8. Spirochetes and Zoonotics
277
9. Mycobacteria279
10. Nonstaining Bacteria
281
11. Penicillins283
12. Cephalosporins 285
13. Other Cell Wall Inhibitors
287
14. Protein Synthesis Inhibitors
289
15. Other Antibiotics
292
16. Micro by Systems part 1
295
17. Micro by Systems part 2
298
18. Viral Basics
301
19. DNA Viruses part 1
303
20. DNA Viruses part 2
306
21. RNA Viruses part 1
308
22. RNA Viruses part 2
310
23. HIV313
24. HIV Drugs
315
25. Mycology part 1
318
26. Mycology part 2
320
27. Antifungals322
28. Protozoa325
29. Helminths and Ectoparasites
328
TABLE OF CONTENTS
TABLE OF CONTENTS
IMMUNOLOGY
1.
2.
3.
4.
5.
6.
7.
8.
9.
Immune System Basics
333
Antigen Presentation
335
T Cells
337
B Cells and Antibodies
339
Immunization and Autoantibodies
341
Hypersensitivity and Complement 344
Macrophages, Granulocytes and Cytokines
346
Immunosuppressants348
Immunodeficiencies350
[ iii ]
TABLE OF CONTENTS
TABLE OF CONTENTS
IX
X
XI
[ iv ]
GI
1. Oropharynx357
2. Esophagus361
3. Stomach364
4. Upper GI Pathology
366
5. Duodenum368
6. Enterocytes and Absorption
370
7. Diseases of the Small Intestine
372
8. Large Intestine part 1
374
9. Large Intestine part 2
376
10. Large Intestine part 3 378
11. Pancreas380
12. Liver Basics
382
13. Alcoholic Liver Disease and Cirrhosis
384
14. Liver Pathology
386
15. Hepatitis388
16. Biliary Tract
390
PULMONARY
1. Anatomy and Physiology
395
2. Lung Volumes and Pulmonary Circulation
397
3. Oxygen and Hemoglobin 400
4. Oxygenation402
5. Ventilation and Perfusion
404
6. Extreme Environments
406
7. PE, DVT and Pneumothorax
409
8. COPD and Asthma
411
9. Pulmonary Medications
413
10. Restrictive Lung Disease
415
11. Lung Cancer
418
12. Lung Infections
420
MEDICINE IN SOCIETY
1.
2.
3.
4.
5.
6.
7.
8.
9.
Research Study Designs
425
Diagnostic Test Evaluation
427
Interpretation of Study Data
429
Study Validity
432
Statistical Distribution and Error
434
Biostatistics436
Disease Prevention and Public Health 438
Healthcare System
442
Ethics448
XII
XIII
XIV
BIOCHEM
TABLE OF CONTENTS
TABLE OF CONTENTS
1. DNA Basics
453
2. DNA Replication, Mutation and Repair
457
3. RNA460
4. Protein Synthesis
464
5. Inheritance466
6. Genetic Lab Techniques
469
7. Glycolysis472
8. Gluconeogenesis476
9. Glycogen479
10. Energy Metabolism
482
11. HMP Shunt and Other Sugars
486
12. Starvation and Malnutrition
488
13. Lipids491
14. Amino Acids and Nitrogen
494
15. Amino Acid Disorders
496
16. Minerals498
17. Fat-Soluble Vitamins and Antioxidants
500
18. Water-Soluble Vitamins
502
PSYCH
1. Psychology507
2. Child Psych
509
3. Eating Disorders
511
4. Alcohol Abuse
513
5. Substance Abuse
516
6. Psychosis518
7. Antipsychotics520
8. Bipolar Disorder
522
9. Depression524
10. Antidepressants526
11. Anxiety and Somatoform Disorders
528
12. Ego Defense Mechanisms and Personality Disorders
530
RENAL
1. Renal Embryology and Anatomy
535
2. Glomerular Physiology
537
3. Nephron Physiology
539
4. Diuretics544
5. Electrolyte Disorders
546
6. Acid-Base Disorders
548
7. Nephritis550
8. Nephrosis552
9. Other Renal Pathology part 1
554
10. Other Renal Pathology part 2
556
[v]
TABLE OF CONTENTS
TABLE OF CONTENTS
XV
XVI
PEDIATRICS
1. Pediatric Review
560
ENDOCRINE
1. Endocrine Overview
567
2. Pituitary569
3. Adrenal Steroid Synthesis
573
4. Glucocorticoids and Cushing Syndrome
576
5. Other Adrenal Pathology
578
6. Thyroid Basics and Hyperthyroidism
580
7. Hypothyroidism and Thyroid Cancer
582
8. Diabetes584
9. DKA and Diabetes Treatment
586
10. Obesity 590
11. Calcium Metabolism
592
XVII HEME
1. Clotting Factors
597
2. Anticoagulant Drugs
599
3. RBC Basics
601
4. Erythropoiesis603
5. Nonhemolytic Anemias
605
6. Hemolytic Anemias
607
7. Platelet Function
610
8. Platelet Disorders
612
9. Lymphoma614
10. Leukemia and Multiple Myeloma
616
XVIII ONCOLOGY
1.
2.
3.
4.
5.
6.
[ vi ]
Cancer Basics
Genetics of Cancer Cancer Risk Factors
Cancer Screening and Prevention
Cancer Drugs part 1
Cancer Drugs part 2
621
623
626
628
630
632
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