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HAEMORRHAGIC DIATHESES DUE TO VASCULAR DISORDERS A. B. Inherited Vascular Bleeding Disorders Acquired Vascular Bleeding Disorders Inherited Vascular Bleeding Disorders 1. Hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu disease) 2. Inherited disorders of connective tissue matrix Acquired Vascular Bleeding Disorders 1. 2. 3. 4. 5. 6. 7. 8. Henoch-Schönlein purpura Haemolytic-uraemic syndrome Simple easy bruising (Devil’s pinches) Infection Drug reactions Steroid purpura Senile purpura Scurvy HAEMORRHAGIC DIATHESES DUE TO PLATELET DISORDERS A. Due to reduction in the number of platelets i.e. various forms of thrombocytopenias. B. Due to rise in platelet count i.e. thrombocytosis. C. Due to defective platelet functions. THROMBOCYTOPENIAS 1. 2. 3. 4. Impaired platelet production. Accelerated platelet destruction. Splenic sequestration. Dilutional loss.