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Anatomy and Physiology – Chapter 4: Skin and Body Membranes (Integumentary System) Pages (109 – 130) Body membranes, which cover surfaces, line body cavities and form protective (and often lubricating) sheet around organs. Classification of Body Membranes Epithelial membranes * Cutaneous (skin) * Mucous – (mucosa) * Serous - Serous fluid - Peritoneum - Pleura - Pericardium Connective tissue membranes * Synovial membranes - Bursae - Tendon sheaths Integument Skin – the largest organ and is called the cutaneous membrane Functions of the Skin Layers of the Skin Epidermis – (outer layer) – avascular (has no blood supply of its own) - keratinocytes – keratin cells – make up most of the epidermis - has 5 layers called strata: * stratum basale * contains melanin * stratum spinosum * stratum granulosum * stratum lucidum * stratum corneum • Dermis – (middle layer) – your “hide” – sensory receptors, blood vessels, and glands 2 Major Regions • Papillary Layer • Reticular Layer - Bedsores – decubitus Hypodermis or Subcutaneous Skin Color • How skin color is determined • Skin Color Alterations: Appendages of the skin Cutaneous glands (sweat glands) Hair Nails Cutaneous Glands (exocrine glands) Sebaceous – (oil glands) Sudoriferous – (sweat glands) - Eccrine – more numerous - Aprocrine – axillary and genital areas Hair – – Protective Functions: Produced by a hair follicle • Root – encloses the hair in the follicle • Hair bulb matrix • Shaft – What are “Goose bumps”. – – A nail is a scale-like modification of the epidermis; similar to a hood or claw of other animals Nail matrix is responsible for nail growth • As nail cells are produced by the matrix, they become keratinized and die; so like hair, most is nonliving material Transparent and colorless, but look pink due to the rich blood supply in the underlying dermis Nails – Homeostatic Imbalances of the Skin Allergies o Contact dermatitis Infections o Bacterial Boils and carbuncles Impetigo o Viral Cold sores (fever blisters) o Fungal Athlete’s Foot Acne Psoriasis Burns Skin Cancer • Types of Skin Cancer – Basal Cell Carcinoma – Squamous Cell Carcinoma – Malignant – ABCD Rule: » Asymmetry » Border Irregularity » Color » Diameter Developmental Aspects of Skin