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Introduction to Cardiovascular Physiology Jim Pierce Bi 145a Lecture 10, 2009-10 Cardiovascular System Our Goals: – Anatomy and Core Principles – Cardiac Electrophysiology – Cardiac Mechanical Function – Vascular Function – Integrated Picture Cardiovascular System The Pump The Heart (Vascular System) The Pipes Pulmonary Circulation Systemic Circulation The Heart Mediastinum Mediastinum, Heart Exposed Mediastinum without Heart Pericardium without Heart Heart, Left Lateral View The Heart Components of the Heart – Cardiac Skeleton and Valves – Epicardium and Epicardial Vessels – Myocardium and Penetrating Vessels – Endocardium – Electrical System The Heart Cardiac Skeleton The primary skeletal structures surround the Valves Annulus Fibrosis Fibrous Trigone Cardiac Skeleton Valve Annulus Fractured SEM Mallory’s Trichrome Cardiac Skeleton Higher Power Cardiac Skeleton Cardiac Valves Cardiac Valves Cardiac Valves Layers of the Heart Epicardium Yes, That’s Fat Epicardium The Epicardium supports the coronary vasculature Myocardium Endocardium Heart, Anterior View Heart, Posterior View Heart, Posterior Inferior View Cardiac Vessels, Anteriorly Cardiac Vessels, Posteriorly Right Atrium Right Ventricle Left Atrium and Ventricle Left Ventricle Artery Vein Aortic Arch Thoracic Aorta Abdominal Aorta Inferior Vena Cava Superior Vena Cava Portal Venous System Thoracic Vessels Abdominal Vessels Extremity Vessels Calf Pump Muscular Artery Muscular Artery Artery and Vein Neurovascular Bundle Small Artery and Vein Arterioles Capillaries and Venules Blood Vessels Blood Flow Cardiac Cycle The heart squeezing is called Systole The heart relaxing is called Diastole Preload Afterload Valves During Systole Valves During Diastole Videos