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MIDTERM PROJECT Augmentin®Oral Preparations Indication: Amoxicillin-clavulanate should be used in accordance with local official antibioticprescribing guidelines and local susceptibility data. Contraindication: Co-amoxiclav is contraindivated - In patients with a history of hypersensitivity to beta-lactams, e.g penicillins and cephalosporins. -In patients with a previous history of amoxicillinclavulanate-associated jaundice/hepatic dysfunction. Dosage and Administration: Dosage depends on the age, weight and renal function of the patient and the severity of the infection. APROVEL Indication: Treatment of essential hypertension. Treatment of trenal disease in patients with hypertension and type two diabetes mellitus as part of an antihypertensive drug regimen. Contraindication: Hypersensitivity to any component of the product. Second and third trimester of pregnancy. Dosage and Administration: The usual recommended initial and maintenance dose is 150mg once daily with or without food. Thorazine® Indication: For the management of manifestation psychotic disorders. To control nausea and vomiting. For relief of restlessness and apprehension before surgery. Contraindication: Do not use in comatose states or in the presence of large amounts of central nervous system depressants. Dosage and Administration: Choropolzamine HCl should generally not used in children under 6 months of age except where potentially lifesaving. Zinnat® Tablets Indication: It is an oral prodrug of the bacterial cephalosporin antibiotic cefuxime whichis resistant to most B-lactameses and is active againts a wide range of Gram-positive and Gram-negative organisms. Contradictions: Patients with known hypersensitivity to cephalosporin antibiotics. Dosage and Administration: The usual course of therapy is seven days range to 5 days. Cefuroxime should be taken after food for optimum absorption. Flanax® Forte Indication: Naproxen Sodium is indicated in the relief of mild to moderately severe pain with or without accompanied inflammation. Contraindications: It is contraindicated in patients with history of hypersensitivity to aspirin of any other NSAIDs. Dosage and Administrations: The recommended dose is one tablet twice daily. Diamicron® MR Indication: For non-insulin-dependent diabetes(type 2), in association with dietary measures and with exercise, when these measures alone are not sufficient. Contraindication: Diamicron®MR should not be used in this case: -Allergy to this medicine or to other medicines of the same group(sulfonylureas). Dosage and Administration: The usual daily dosage 1 to 4 tablets per day as a single dose. It is recommended that the drug be taken at breakfast time. Fluimucil® Indication: Treatment of respiratory affections characterized by thick and viscous hypersecretion due to bronchitis, chronic bronchitis and its exabertion. Contraindications: Known hypersensitivity to acetylcysteine. Fluimicil granules and tablets are contraindicated in patients suffering from phenylketonuria due to the aspartame content. Dosage and Administration: 1 sachet of FLUIMUCIL® 100 mg, 2 to 4 times a day, according to age. ADALAT® Indication: Treatment of coronary heart disease. Chronic stable pectoris, treatment of hypertension. Contraindication: It is must not be used in cases of known hypersensitivity to nifedipine or to any of the excipients. Dosage and Administration: As far as possible the treatment must be tailored to the individual. Depending on the clinical picture in each case, the basic dose must be introduced gradually. Arcoxia/Arcoxia Ac Indication: Relief of acute pain, treatment of primary dysmenorrhoea, and treatment of acute gouty arthritis. Contradiction: Active peptic ulceration or active gastro-intestinal bleeding. Patients who have experienced bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions after taking acetylsalicylic acid. Dosage and Administration: It is administered orally , may be taken with or without food. Celebrex ® Indication: Symptomatic treatment of osteoarthritis and rheumatoid arthritis, relief of signs and symptoms of ankylosing spondylitis, management of acute pain, for the treatment of primary dysmenorrhea. Contraindications: Patients who have experienced asthma, urticaria or allergic-type reactions after taking surgery. Dosage and Administration: Celecoxib should be used with caution when treating patients with moderate hepatic impairment. Prepared by: Justine Cris A. Cenizan Crisanto Lacusong