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Anatomy and Physiology 2211K Lecture Five Slide 2 – Urinary system Slide 3 – Urinary system’s function – filtering the blood Slide 3 – Urinary system’s function – regulation of blood volume Slide 3 – Urinary system’s function – regulation of ions Slide 6 – Urinary system’s function – pH regulation Slide 7 – Urinary system’s regulation - hormonal Slide 8 – Urinary system’s regulation – Vitamin D Slide 9 - Kidneys Slide 10 - Nephron Slide 11 – Histology of the nephron (glomerulus) Slide 12 – Histology of the nephron (Bowman’s capsule) Slide 13 – Histology of the nephron (Proximal convoluted tubule) Slide 14 – Histology of the nephron (distal convoluted tubule) Slide 15 – Histology of the nephron – juxtaglomerular apparatus Slide 16 – Blood flow of the nephron and the kidneys Slide 17 – Ureter and the urinary bladder Slide 11 – urine formation Slide 19 – Urea cycle Slide 20 – Uric acid production Slide 21 – Renal filtration Slide 22 – Renal fraction Renal plasma flow rate - the actual flow of plasma reaching the kidneys is equal to the renal blood flow rate multiplied by the portion of the blood that is made up of plasma – which is approximately 55% 1176mL/min x 0.55 = 646 mL plasma /min Filtration fraction – the actual part of the plasma that is being filtered through the glomerulus and the renal capsule. Filtration fraction averages 19% of the plasma flowing through the kidneys 646 mL plasma/min x 0.19 = 123.5 mL plasma per minute Slide 23 – Urine formation - glomerulus Slide 23 – Filtration pressure Slide 23 – reabsorption – proximal convoluted tubule Slide 25 – Reabsorption – loop of Henle Slide 26 – Ascending loop of Henle Slide 26 – reabsorption – distal convoluted tubule Slide 28 – Urine concentration