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Meiosis
A REDUCTION DIVISION TO PRODUCE
GAMETES WHICH ULTIMATELY MAINTAINS A
CONSISTENT CHROMOSOME NUMBER IN THE
SPECIES
PART 2
Prophase in Meiosis
http://biowiki.ucdavis.edu/Genetics/Unit_II%3A_Replication,_Maintenance_and_Alteration_of_the_Genetic_Material/8._R
ecombination_of_DNA/Meiotic_recombination
https://creativecommons.org/licenses/by-nc-sa/3.0/us/ No changes have been made.
Leptotene Stage of Prophase I in Meiosis
Homologous Chromosome Pair
Cell Membrane
Paternal
Sister
Chromatids
Centromere
Drawing: Lynda Jones, MS, ONPRC
Centromere
Nuclear
Membrane
Maternal Sister
Chromatids
Zygotene Stage of Prophase I of Meiosis
Synapsis
http://commons.wikimedia.org/wiki/File:Tetrad.png
http://creativecommons.org/licenses/by-sa/2.5/deed.en No changes were made
Synapsis
https://www.boundless.com/biology/textbooks/boundless-biology-textbook/meiosis-and-sexual-reproduction11/the-process-of-meiosis-92/meiosis-i-404-11631/images/fig-ch11-01-01/
http://creativecommons.org/licenses/by-sa/4.0/ No changes were made.
Formation of the Sex Body in the Late Zygotene-Early
Pachytene Stage of Prophase I of Meiosis in the Testes
SRY Gene
Paternal Y Sister
Chromatids
Pseudoautosomal Region (PAR) where
the X and Y chromosomes synapse or
forming a fused X and Y tetrad known
as the sex body
Centromeres
Other PAR
regions
Maternal X Sister Chromatids
SRY is the Sex-determining Region Y gene
(also known as the TDF or Testis-Determining Factor gene).
Drawing: Lynda Jones, MS, ONPRC
Crossing Over - Pachytene Stage of Prophase I of Meiosis
https://upload.wikimedia.org/wikipedia/commons/0/0e/Morgan_crossover_1.jpg Public Domain
Frans Alfons Janssens
(1865 – 1924)
Discovered and described
crossing- over in chromosomes
during meiosis which he called
‘chiasmatypie’ - 1909
http://en.wikipedia.org/wiki/File:Frans_Janssens.jpg Public Domain
Thomas Hunt Morgan
(1866-1945)
• Discovered sex-linked genes and
did further work on crossing over
based on Janssens’ work and
provided the first true genetic
interpretation of meiosis
• Won Nobel Prize in Physiology or
Medicine in 1933 “for his
discoveries concerning the role
played by the chromosome in
heredity”
http://www.nobelprize.org/nobel_prizes/medicine/
laureates/1933/
http://upload.wikimedia.org/wikipedia/commons/8/8f/Thomas_Hunt_Morgan.jpg Public Domain
http://cnx.org/contents/[email protected]:57/Biology
http://creativecommons.org No changes were made.
Homologous Chromosomes in the Diplotene Stage
of Prophase I of Meiosis
Maternal
Sister
Chromatids
Paternal
Sister
Chromatids
Centromeres
Drawing: Lynda Jones, MS, ONPRC
Chiasmata
https://en.wikibooks.org/wiki/Medical_Physiology/Cellular_Physiology/DNA_and_Reproduction#/media/File:Meiosis.png
By Boumphreyfr (Own work) [CC BY-SA 3.0 (http://creativecommons.org/licenses/by-sa/3.0) No changes were made.
The Origin of Aneuploidy Gametes by
Nondisjunction in Meiosis
http://upload.wikimedia.org/wikipedia/commons/3/31/Mitotic_nondisjunction.png http://creativecommons.org/licenses/bysa/3.0/deed.en No changes have been made.
The Origin of Aneuploidy Gametes by Nondisjunction
at the First or Second Meiotic Division
http://upload.wikimedia.org/wikipedia/commons/b/ba/Trisomy_due_to_nondisjunction_in_maternal_meiosis_1.png
http://creativecommons.org/licenses/by-sa/3.0/deed.en No changes have been made.