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Calcium Chloride 注射液 成份 CaCl2 適應症 Listed in Dosage. 用量 1. Hypocalcaemia 10-25 mmol at intervals of 1-3 days, depending on patient's response. 2. Severe acute hypocalcaemia; Hypocalcaemic tetany 2.25 mmol, repeat when needed. 3. Antidote in severe hypermagnesaemia; 4. Severe hyperkalaemia As 10% soln: 5-10 mL, repeat when needed w/ ECG monitoring. Contraindications 1. Treatment of hypocalcaemia caused by renal insufficiency or in patients with resp acidosis or failure. 2. Patients with Ca renal calculi or a history renal calculi; IM/SC administration. 3. Parenteral therapy for patients receiving cardiac glycosides. Special 1. Impaired renal function; Precautions 2. Cardiac disease; 3. Hypercalcaemia-associated diseases, eg, sarcoidosis; other malignancies. 4. Pregnancy. Adverse Drug Reactions 1. GI irritation: Soft-tissue calcification, skin sloughing or necrosis after IM/SC injection. 2. Hypercalcaemia characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, nephrocalcinosis, renal calculi; chalky taste, hot flushes and peripheral vasodilation. 3. Potentially Fatal: Cardiac arrhythmias and coma. Drug Interactions 1. Co-administration of high Ca doses with thiazide diuretics may result in milk-alkali syndrome and hypercalcaemia. 2. May potentiate digoxin toxicity. 3. Decreases effects of calcium-channel blockers. 4. Enhanced absorption with calcitriol (a vit D metabolite). 美國食品藥物管 理局之懷孕等級 治療分類 Intravenous & Other Sterile Solutions 劑型包裝 1.Calcium Chloride 注射劑 2.Calcium Chloride 5 % x 20 mL 圖片 參考文獻:MIMS