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(A) Somatosensory afferents also synapse with two different types of neurons—one excitatory synapse with an excitatory interneuron (1) and one
excitatory synapse with the wide dynamic range cell. The excitatory interneuron makes an excitatory synapse with the inhibitory interneuron and the wide
dynamic range cell. Nociceptive afferent makes two synapses—one inhibitory synapse with an inhibitory interneuron (2) and one excitatory synapse
directly with the wide dynamic range cell. The inhibitory interneuron synapses with the wide dynamic range cell. (B) When somatosensory input is greatest,
touch signals are propagated in two ways. The cutaneous afferent excites the wide dynamic range cell directly and indirectly through activating the
excitatory interneuron. (C) When nociceptive input is greatest, pain signals are propagated in two ways. The pain afferent excites the wide dynamic range
Source: Diagnostic Considerations of Pain, Diagnosis for Physical Therapists: A Symptom-Based Approach
cell directly and indirectly by inhibiting the inhibitory interneuron. (D) When somatosensory and nociceptive input are present, input from the
Citation:
Davenport
K, Sebelski
CA, signals
Gordonby
J, activating
Watts HG.the
Diagnosis
Physical Therapists:
A Symptom-Based
Approach;
2013
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Accessed:
May
11,
2017
projection neurons in the raphe nucleus of the medulla reduces the transmission of nociceptive signals directly by inhibiting the wide dynamic range cell
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and indirectlyCopyright
by exciting
inhibitory
interneuron.