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Abnormal EEG brain in neurological disease แพทย์หญิง กาญจนา พิทกั ษ์วฒ ั นานนท์ อายุรแพทย์ผเู ้ ชี่ยวชาญระบบประสาท แพทย์ประจาศูนย์สมอง โรงพยาบาลสมิติเวชศรีราชา 10 – 20 system Records the difference between two Active scalp electrodes Bipolar montage Active scalp electrode Inactive scalp / ear electrode : A1 , A2 Referential montage Reference / Bipolar montage If the voltage input from electrode 2 is relatively “ positive ” compared to electrode 1 , then the pen will deflect “ up ” If electrode 2 is relatively “ negative ” compared to electrode 1 , then the pen will deflect “ down ” If electrode 1 equal to electrode 2 , then the pen stay “ baseline ” Polarity Different Montage : Polarity Identify background rhythms ( frequency Alpha 8 -13 Hz Beta 13 – 40 Hz Theta 4 – 8 Hz Delta < 4 Hz Mu 7 – 11 Hz Sleep stage ( awake , NREM , REM ) ) Identify any abnormal patterns Slow patterns Diffusely , Focally Symmetry , Asymmetry Paroxysms Spike , spike and wave complex , sharp wave Triphasic waves PLEDs ( Periodic lateralizing epileptiform discharges ) Localize those abnormal patterns Maximum amplitude ( Referential montage ) Phase reversal / Reciprocal changes ( Bipolar montage ) EEG interpretation Background rhythm / frequency Sleep stage : Background Epilepsy Common ◦ Sleep deprivation ◦ ◦ ◦ ◦ ◦ , Alcohol withdrawal , Television flicker , Systemic infection , Head trauma , Recreational drugs , antiepileptic drug , Menstruation Occasional ◦ Dehydration , ◦ Barbiturate / Benzodiazepine withdrawal , ◦ Hyperventilation , ◦ Flashing lights , ◦ Diet and missed meals , ◦ Specific reflex trigger , ◦ Stress , Intense exercise Factor lowering seizure threshold Rountine electroencephalograms ◦ Hyperventilation ◦ Photic stimulation ◦ Sleep-deprivation Prolonged ambulatory recording Video – EEG telemetry Magnetoencephalography : Research Activation tecniques ( EEG ) Seizure Epileptiform discharge / Spike Focal seizure : spike ( phase reversal ) PLEDs ( Periodic lateralizing epileptiform discharges ) Herpes simple encephalitis Ictal EEG : Spike and waves complexs Generalized seizure Absence seizure 3 Hz spike and wave complexs Syndrome of epilepsy Syndrome of epilepsy CJD – Mad cow disease Diffused slow pattern : encephalopathy Triphasic waves Prion encephalitis Severe dementia Triphasic waves : degenerative disease Encephalopathy Comatose Brain death Sleep or Death Sleep Spindle Sleep spindle / K complex Sleep Sleep Lab / Polysomnography Hypnogram Eye Blink Artifact Artifact