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Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
1.
Introduction to Cardiovascular Pathophysiology
2.
Coronary Anatomy
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 1
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
3.
Actin-Myosin Structure
4.
The Sarcomere’s Contractile Proteins
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 2
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
5.
Excitation-Contraction Coupling
6.
Excitation-Contraction Coupling
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 3
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
7.
The Cardiac Electrical System
8.
The Cardiac Cycle
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 4
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
9.
Heart Sounds
10.
The Cardiac Cycle
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 5
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
11.
Components of Diastole
12.
Introduction to Cardiovascular Pathophysiology: Slide 12
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 6
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
13.
Determinants of Cardiac Output
14.
Determinants of Cardiac Output
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 7
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
15.
Determinants of Cardiac Output
16.
Determinants of Cardiac Output
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 8
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
17.
Determinants of Cardiac Output Contractility
18.
Left Ventricular Ejection Fraction
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 9
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
19.
Determinants of Cardiac Output
20.
The Pressure-Volume Loop
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 10
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
21.
The Pressure-Volume Loop Decline in Inotropy
22.
The Pressure-Volume Loop Increase in Afterload
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 11
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
23.
The Pressure-Volume Loop Decrease in Preload
24.
Pressure Volume Loop
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 12
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
25.
Flow Volume Loops (The Cardiac Cycle)
26.
Flow Volume Loops (The Cardiac Cycle)
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 13
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
27.
Intra Cardiac Diastolic Pressures
28.
Normal Intracardiac Pressures
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 14
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
29.
Hemodynamic Measurement
30.
Determinants of Blood Pressure
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 15
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
31.
Hypovolemic Shock (Hemorrhage, Dehydration)
32.
Cardiogenic Shock (Post Extensive Myocardial Infarction)
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 16
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
33.
Hypotension Secondary to Slow Heart Rate
34.
Hypotension Secondary to Anaphylactic Shock or Sepsis
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 17
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
35.
Measuring Vascular Resistance
36.
The Monophasic Action Potential (MAP)
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 18
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
37.
Monophasic Action Potential (Cardiac Muscle Cell)
38.
Monophasic Action Potential (Effect of Potassium Channel Blo...
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 19
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
39.
Effect of Potassium Channel Blockage
40.
Monophasic Action Potential (Cardiac Muscle Cell)
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 20
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
41.
Monophasic Action Potential (Cardiac Pacemaker Cell)
42.
Monophasic Action Potential (Cardiac Pacemaker Cell)
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 21
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
43.
The Monophasic Action Potential
44.
Conduction of Cardiac Impulse
OCW: Cardiovascular Pathophysiology (M. Homoud)
Page - 22
Tufts OpenCourseWare
© 2008 Tufts University
Introduction to Cardiovascular Pathophysiology
45.
OCW: Cardiovascular Pathophysiology (M. Homoud)
The Cardiac Cycle
Page - 23
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