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A. LV function every 20 min in normal hearts subjected to 4 h of aortic clamping with blood cardioplegia compared with depressed function after 45 min of
normothermic arrest without cardioplegia. B. LV function when jeopardized hearts undergoing 45 min of normothermic ischemia are subjected to 2 h more
of aortic clamping. Note (1) no further improvement when only cold cardioplegic perfusate is given over the 45-min arrest period and (2) progressively
increased recovery when the cardioplegic solution is supplemented with warm glutamate and aspartate during induction of cardioplegia and reperfusion
with intermittent cold doses of blood every 20 min of supplemental aortic clamping. These data suggest the value of amino acid enrichment in jeopardized
hearts. LAP, left atrial pressure; SWI, stroke-work index.
Source: Myocardial Protection, Johns Hopkins Textbook of Cardiothoracic Surgery
Citation: Yuh DD, Vricella LA, Yang SC, Doty JR. Johns Hopkins Textbook of Cardiothoracic Surgery; 2014 Available at:
http://accesssurgery.mhmedical.com/ViewLarge.aspx?figid=55169962&gbosContainerID=0&gbosid=0 Accessed: May 10, 2017
Copyright © 2017 McGraw-Hill Education. All rights reserved
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