Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Alpine Animal Hospital Debra M. Taylor, D.V.M. Patti A. Tuck, D.V.M. Emily A. Lewis, D.V.M. 2202 E. M-32 Gaylord, MI 49735 (989)732-6427 (989)732-4561 Fax Email: [email protected] www.alpineanimalhospitalmi.com Multidrug Sensitivity in Dogs Many herding breed dogs have a genetic predisposition to adverse drug reactions involving over a dozen different drugs. The most serious adverse drug reactions involve several antiparasitic agents (ivermectin, milbemycin and related drugs), the antidiarrheal agent loperamide (Imodium), and several anticancer drugs (vincristine, doxorubicin, others). These drug sensitivities result from a mutation in the multidrug resistance gene (MDR1 gene). At Washington State University's College of Veterinary Medicine you can test your dog for multidrug sensitivity and prevent serious adverse drug reactions. We can work with your dog’s veterinarian to find appropriate drug doses or alternative drugs for your dog based on results of MDR1 testing. The Partnership for Preventive Healthcare, is an initiative jointly sponsored by the American Animal Hospital Association and the American Veterinary Medical Association. Together the two associations offer a set of Canine and Feline Preventive Healthcare Guidelines. One of the important recommendations is that dog owners use genetic testing—like the MDR1 test —as part of an overall healthcare plan for their pets. Most Commonly Affected Breeds Australian Shepherd IMPORTANT NOTICE The discovery of the mutation of the multi-drug Australian Shepherd (Mini) resistant gene (mdr1), establishment of testing Collie procedures, and development of all reagents Long-haired Whippet was made by Washington State University. It is McNab also a patent protected diagnostic test offered Silken Windhound exclusively by Washington State University that has not been licensed to any other entity in the United States. It is licensed in Australia and Europe. Any unlicensed use or marketing of the patented test is a violation of federal statute under 35 u.s.c. 271. Unless testing is conducted by Washington State University's Veterinary Clinical Pharmacology Laboratory, Washington State University cannot control quality and accuracy and consumers may risk receiving inaccurate results.