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providers.amerigroup.com CPT code changes for 2015: Drug screening services CPT 2015 has made significant changes to drug procedure codes. Codes 80100-80102 (qualitative drug screen and drug confirmation) have been deleted and replaced by new codes, 80300-80304. Additional new codes describe individual drug testing procedures. DELETED CODES CPT code 80100 80101 80102 CPT code 80300 80301 80302 80303 80304 LAPEC-0663-15 Description Drug screen, qualitative; multiple drug classes chromatographic method, each procedure Drug screen, qualitative; single drug class method (i.e., immunoassay, enzyme assay), each drug class Drug confirmation, each procedure NEW CODES Description Drug screen, any number of drug classes from Drug Class List A; any number of non-TLC devices or procedures, (i.e., immunoassay) capable of being read by direct optical observation, including instrument-assisted when performed (i.e., dipsticks, cups, cards, cartridges), per date of service Drug screen, any number of drug classes from Drug Class List A; single drug class method, by instrumented test systems (i.e., discrete multichannel chemistry analyzers utilizing immunoassay or enzyme assay), per date of service Drug screen, presumptive, single drug class from Drug Class List B, by immunoassay (i.e., ELISA) or non-TLC chromatography without mass spectrometry (i.e., GC, HPLC), each procedure Drug screen, any number of drug classes, presumptive, single or multiple drug class method; thin layer chromatography procedure(s) (TLC) (i.e., acid, neutral, alkaloid plate), per date of service Drug screen, any number of drug classes, presumptive, single or multiple drug class method; not otherwise specified presumptive procedure (i.e., TOF, MALDI, LDTD, DESI, DART), each procedure