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CURRICULUM VITAE
Name:
Lawrence S. Lee, M.D.
Office Address:
University Heart Surgeons
University of Tennessee Graduate School of Medicine
1940 Alcoa Highway, Suite E-260
Knoxville, Tennessee 37920
Work Phone:
865-305-6955
Work Email:
[email protected]
Work Fax:
865-305-8238
Place of Birth:
Seoul, South Korea
Education
2001
B.S.
magna cum laude
Biology
Haverford College
Haverford, PA
2005
M.D.
Medicine
University of Pennsylvania
School of Medicine
Philadelphia, PA
Postdoctoral Training
2005-2006
Intern
Surgery
Brigham and Women’s Hospital
Harvard Medical School
2006-2007
Junior Resident
Surgery
Brigham and Women’s Hospital
Harvard Medical School
2010-2011
Senior Assistant
Resident
Surgery
Brigham and Women’s Hospital
Harvard Medical School
2011-2012
Senior Resident
Surgery
Brigham and Women’s Hospital
Harvard Medical School
2012-2013
Chief Resident
Surgery
Brigham and Women’s Hospital
Harvard Medical School
2013-2014
Resident
Thoracic Surgery
Brigham and Women’s Hospital
Harvard Medical School
2014-2015
Chief Resident
Thoracic Surgery
Brigham and Women’s Hospital
Harvard Medical School
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Academic Appointments
2005-2015
Clinical Fellow
Surgery
Harvard Medical School
2015-
Assistant Professor
Surgery
University of Tennessee
Graduate School of Medicine
Current Licensure and Certification
2007
Massachusetts
License # 230898
2013
American Board of Surgery
Certificate # 058458
2015
Tennessee
License # 52780
Honors and Prizes
2000
Interdisciplinary
Scholar
Howard Hughes Medical Institute
Scientific Achievement
and Merit
2000
Phi Beta Kappa
Haverford College
Scholarship
2002
Research Fellowship
National Institutes of Health
National Institute of Diabetes and
Digestive and Kidney Diseases
Scientific Achievement
and Merit
2004
Student Representative
to ACS Clinical
Congress
University of Pennsylvania School
of Medicine
Leadership Potential
2007
Warren Whitman
Fellowship
Harvard Medical School
Research, Scientific Merit,
Leadership Potential
2008
Research Fellowship
(awarded but declined)
Heart Failure Society of America
Research and Scientific
Merit
2008
T32 Research Grant
National Institutes of Health
Harvard Longwood Area
Cardiovascular Surgery Grant
Research
2009
John A. Mannick
Award
Harvard Medical School
Scientific Achievement
and Merit
2010
Richard C.
Lillehei/Earl Bakken
Prize
Lillehei Surgical Society
University of Minnesota
Scholarship, Merit,
Leadership Potential
2
Research Training
2002
Research Fellow
Thoracic Oncology Research Laboratory, University of Pennsylvania School of Medicine
Advisor: Larry Kaiser, M.D.
Analyzed gene expression and regulation in lung adenocarcinoma and mesothelioma using
real time quantitative PCR and genomic profiling algorithms
2004-2005
Research Fellow
Surgical Oncology Research Laboratory, University of Pennsylvania School of Medicine
Advisor: Douglas Fraker, M.D.
Performed in vivo and in vitro experiments investigating the mechanism of action of
isolated limb perfusion chemotherapy for extremity melanoma and sarcoma
2007-2010
Postdoctoral Research Fellow
Cardiac Surgery Research Laboratory, Harvard Medical School
Advisor: Frederick Chen, M.D., Ph.D.
Performed large animal (ovine) studies to investigate the effects of adjustable ventricular
restraint therapy as a novel surgical treatment for heart failure
Teaching Appointments
2008
Preceptor
Introduction to Clinical Medicine
Harvard Medical School
Second year medical student course
focusing on physical exam and patient
interaction skills
2009
Preceptor
Human Body Anatomy
Harvard Medical School
First year medical student anatomy course
2009
Preceptor
Advanced Clinical Anatomy
Harvard Medical School
Advanced anatomy course for fourth year
medical students
Publications
Peer reviewed publications
1. Lee L, Singhal S, Brinster C, Marshall B, Kochman M, Kaiser L, Kucharczuk J. Current
management of esophageal leiomyoma. J Am Coll Surg 2004; 198(1):136-146.
2. Brinster C, Singhal S, Lee L, Marshall B, Kochman M, Kaiser L, Kucharczuk J. Evolving options
in the management of esophageal perforation. Ann Thorac Surg 2004; 77:1475-1483.
3. Lee L, Nance M, Kaiser L, Kucharczuk J. Familial massive leiomyoma with esophageal
leiomyomatosis: an unusual presentation in a father and his two daughters. J Ped Surg 2005;
40(5):e29-e32.
4. Lee L, Canter R, Fraker D. Intraoperative jugular venous sampling aids detection of an
undescended parathyroid adenoma. World J Surg 2006; 30(4):620-623.
5. Ghanta R, Rangaraj A, Umakanthan R, Lee L, Laurence R, Fox J, Bolman R, Cohn L, Chen F.
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Adjustable, physiologic ventricular restraint improves LV mechanics and reduces dilatation in a
chronic ovine model of heart failure. Circulation Mar 2007; 115:1201-1210.
6. Ghanta R, Lee L, Umakantahn R, Laurence R, Fox J, Bolman R, Cohn L, Chen F. Real time
adjustment of ventricular restraint therapy in heart failure. Eur J Cardiothorac Surg Dec 2008;
34:1136-1140.
7. Lee LS, Daniel J. Highlights from the 11th annual scientific meeting of the international society
for minimally invasive cardiothoracic surgery. J Thorac Cardiovasc Surg 2008; 136:1107-1009.
8. Umakanthan R, Ghanta R, Rangaraj A, Lee L, Laurence R, Fox J, Mihaljevic T, Bolman R, Cohn
L, Chen F. Cardioscopic Tricuspid Valve Repair in a Beating Ovine Heart. Heart Surg Forum Apr
2009;12(2):E90-4.
9. Lee LS, Ghanta RK, Mokashi SA, Coelho-Filho O, Kwong RY, Bolman RM 3rd, Chen FY.
Ventricular restraint therapy for heart failure: the right ventricle is different from the left ventricle.
J Thorac Cardiovasc Surg. 2010 Apr;139(4):1012-8.
10. Schmitto JD, Mokashi SA, Lee LS, Laurence R, Schotola H, Coelho-Filho O, Rajab TK, Kwong
R, Bolman RM 3rd, Quintel M, Cohn LH, Chen FY. A novel, innovative ovine model of chronic
ischemic cardiomyopathy induced by multiple coronary ligations. Artif Organs. 2010
Nov;34(11):918-22.
11. Mokashi SA, Schmitto JD, Lee LS, Rawn JD, Bolman RM 3rd, Shekar PS, Couper GS, Chen FY.
Ventricular assist device in patients with prosthetic heart valves. Artif Organs. 2010
Nov;34(11):1030-4.
12. Mokashi SA, Guan J, Wang D, Tchantchaleishvili V, Brigham M, Lipsitz S, Lee LS, Schmitto JD,
Bolman RM 3rd, Khademhosseini A, Liao R, Chen FY. Preventing cardiac remodeling: the
combination of cell-based therapy and cardiac support therapy preserves left ventricular function
in rodent model of myocardial ischemia. J Thorac Cardiovasc Surg. 2010 Dec;140(6):1374-80.
13. Schmitto JD, Lee LS, Mokashi SA, Bolman RM 3rd, Cohn LH, Chen FY. Functional mitral
regurgitation. Cardiol Rev. 2010 Nov-Dec;18(6):285-91.
14. Schmitto JD, Mokashi SA, Lee LS, Popov AF, Coskun KO, Sossalla S, Sohns C, Bolman RM 3rd,
Cohn LH, Chen FY. Large animal models of chronic heart failure (CHF). J Surg Res. 2011
Mar;166(1):131-7.
15. Lee LS, Kwon MH, Cevasco M, Schmitto JD, Mokashi SA, McGurk S, Cohn LH, Bolman III
RM, Chen FY. Postoperative recurrence of mitral regurgitation following annuloplasty for
functional mitral regurgitation. Ann Thorac Surg 2012 Oct;94(4):1211-6.
16. Lee LS, Ghanta RK, Mokashi SA, Coelho-Filho O, Kwong RY, Kwon M, Guan J, Liao R, Chen
FY. Optimized ventricular restraint therapy: adjustable restraint is superior to standard restraint in
an ovine model of ischemic cardiomyopathy. J Thorac Cardiovasc Surg 2013 Mar;145(3):824-31.
17. Cevasco M, Mick SL, Kwon M, Lee LS, Chen EP, Chen FY. True external diameter better
predicts hemodynamic performance of bioprosthetic aortic valves than the manufacturers' stated
size. J Heart Valve Dis 2013 May;22(3):377-82.
18. Kwon MH, Lee LS, Cevasco M, Couper GS, Shekar PS, Cohn LH, Chen FY. Recurrence of mitral
regurgitation after partial versus complete mitral valve ring annuloplasty for functional mitral
regurgitation. J Thorac Cardiovasc Surg 2013 Sep;146(3):616-22.
19. Mokashi SA, Lee LS, Schmitto JD, Ghanta RK, McGurk S, Laurence RG, Bolman RM 3rd, Cohn
LH, Chen FY. Restraint to the left ventricle alone is superior to standard restraint. J Thorac
Cardiovasc Surg 2013 Jul;146(1):192-7.
20. Cevasco M, Kwon M, Fiedler A, Lee LS, Shiao J, Shah RV, Worthington AH, Fox JA, Kwong
RY, Chen FY. Right heart failure: an ischemic model and restraint therapy for treatment. Ann
Thorac Surg 2014 Apr;97(4):1356-62.
21. Lee LS and Shekar PS. Current state-of-the-art device therapy for advanced heart failure. Croat
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Med J 2014 Dec;55(6):577-586.
Book chapters
1. Chen FY, Lee LS, Cohn LH. (2009). Valvular operations. In: AG Little, WH Merrill (Eds.),
Complications in cardiothoracic surgery: avoidance and treatment, 2nd edition, pp. 375-391.
2. Lee LS, Chen FY, Cohn LH. (2009). Management of native valve endocarditis. In: FW Sellke,
PJ del Nido, SJ Swanson (Eds.), Sabiston & Spencer's surgery of the chest, 8th edition, pp.
1259-1266.
3. Lee LS, Tchantchaleishvili V, Chen FY. (2010). Visualization of cardioplegia delivery. In: D
Chambers, G Szabo, B Podesser (Eds.), New solutions for the heart- an update in advanced
perioperative protection.
4. Shekar PS, Lee LS, Cohn LH. (2015). Minimally invasive aortic valve surgery. In: LH Cohn
(Ed.), Cardiac surgery in the adult, 5th edition (in press).
Presentations
1. "Wrap tightness determines rate and degree of reverse ventricular remodeling with ventricular
restraint therapy." Massachusetts Chapter American College of Surgeons 54th Annual Meeting,
Boston, MA, December 2007.
2. "Wrap tightness determines reverse remodeling with ventricular restraint therapy." International
Society of Minimally Invasive Cardiothoracic Surgery Annual Meeting, Boston, MA, June
2008.
3. "Quantitative ventricular restraint: a novel therapy for heart failure." Brigham and Women's
Hospital Cardiovascular Interdisciplinary Fellows Annual Conference, Boston, MA, June 2009.
4. "Ventricular restraint: are the right and left really that different?" Western Thoracic Surgical
Association 35th Annual Meeting, Banff, Canada, June 2009.
5. "Ventricular restraint therapy: are the right and left ventricles really different?" Brigham and
Women's Hospital 15th Annual Mannick Research Award Day, Boston, MA, October 2009.
6. "Optimized ventricular restraint therapy for heart failure" Harvard Surgery Inaugural Research
Day, Boston, MA, May 2012
7. "Cardiac Surgery: past its prime or more relevant than ever?" Brigham and Women's Hospital
Department of Surgery Grand Rounds, Boston, MA, February 2013
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