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Number Processing in the Ventral Visual Stream? Zoe Woodhead Robert Leech Richard Wise L Posterior Fusiform R Posterior Fusiform L STS Woodhead et al, In Preparation Polk et al, 2002 Reinke et al, 2008 • To what extent are numbers processed by the ventral visual stream? • Can this be modified by task demands? 5 conditions: 1. Reading words 2. Reading numbers 3. Reading narratives 4. Reading calculations 5. False Font Plus fixation / other neutral stimuli? =24000 -20000 =1200 +1000 =4000 200 x20 mat the cat sat on Design: • ~ 20 right handed, healthy volunteers • Block design – 22.5 second blocks – 12 second inter-block interval • 5 repetitions of each condition per run, 2 runs – Total of 3 min 45 seconds acquisition per condition – Run time total = 14 minutes 10 seconds • Scanning protocol: – 2 second whole-brain EPI, 425 volumes per run – MPRAGE structural scan – Field maps?