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(Form 3) Registration No. Application for the Grant for Challenge Joint Research Program of the Institute for Genetic Medicine (IGM),Hokkaido University (FY 2017) Date: Institution (University, college, etc.) Academic Unit (School, Faculty, etc.) Title Name Address Applicant T E L F A X E-MAIL Research projects of host researchers at IGM *Circle the number of the project(s) applicable to your research project. 1. Regulatory function of noncoding RNAs in various biological control systems:Tetsuro Hirose (RNA Biofunction) 2. Molecular mechanism of tumorigenesis based on cancer stem cell models.:Toru Kondo (Stem Cell Biology) 3. Analyses of innate immune response associate with infection, cancer, and inflammation: Akinori Takaoka (Signaling in Cancer and Immunology) 4. Research for chronic inflammation and organ interactions by neural activations: Masaaki Murakami (Molecular Neuroimmunology) 5. Regulation of cellular responses by the PI3K-AKT mediated signal transduction: Masayuki Noguchi (Cancer Biology) 6. Elucidation of molecular mechanisms for cell competition between normal and transformed epithelial cells: Yasuyuki Fujita (Molecular Oncology) 7. Immune regulation for cancer and transplantation: Ken-ichiro Seino (Immunobiology) 8. Functional control of immune cells and its application to treatment of cancer and infectious disease: Hidemitsu Kitamura (Functional Immunology) 9. Functions and regulation of membrane lipid dynamics: Kazuma Tanaka (Molecular 1 Interaction) 10. Biological mechanisms underlying extraordinary longevity and cancer resistance in naked mole-rat: Kyoko Miura (Biomedical Animal Research Laboratory) 11. Study on mechanism of abnormality in tumor blood vessel endothelial cells: Kyoko Hida (Vascular Biology) 12. Disbalance of neonatal immunity inflammation and oncogenesis: Shinichiro Sawa (Innate lymphoid cell) Is it new or continued Title of Research new・continued Project Research Period From (YMD) to (YMD) Host researcher at IGM Name of division: Name of host researcher: Role of the host researcher in the project proposed: Research collaborators Institution・Academic unit Name Title (e-mail) e-mail: e-mail: e-mail: e-mail: e-mail: e-mail: 2 N Fill out the total amount of expenses for sample shipping and communication (Postage fee) (Not exceed 60,000 yen) yen Purpose of the research project The proposed research plan and methods(State whether the plan contains recombinant DNA experiments or experiments on animals.) Necessity of the joint research with IGM Expected results and significance of the joint research Summary of the results and significance of the previous study if the project proposed is continued one. 3 4