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Digestion, Absorption and Transport The Gastrointestinal Tract Basic anatomy of the GI tract: – mouth – esophagus – stomach – small intestine – large intestine – rectum – anus Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning The Gastrointestinal Tract Accessory organs Salivary glands Liver and gallbladder Pancreas 1 The Gastrointestinal Tract Functions: 9 Ingestion 9 Transport 9 Secretion 9 Digestion 9 Absorption 9 Elimination Digestive Tract Physical Movement: 9 Peristalsis 9 Segmentation Chemical Breakdown: 9 Enzymes 9 Hydrolysis 9 Other secretions Digestive Tract Mouth ¾ Tongue ¾ Teeth (Mastication) Enzymes ¾ Salivary amylase ¾ Lingual lipase 2 Digestive Tract Pharynx Epiglottis Esophagus – transport food to stomach – Esophageal sphincters – Bolus Digestive Tract Stomach Chyme Pyloric sphincter Secretions of Digestion Saliva – Salivary glands Water, salts, mucus, enzymes Muscular Action of Digestive Tract Stomach mechanical action 3 Stomach Muscles Esophegeal Sphincter Muscular Action of Digestive Tract Sphincter contractions – Reflux (heart burn) Pyrolic Sphincter Digestive Tract Esophageal sphincter Stomach Digestion factors: 9 Hydrochloric acid (protein; enzymes activity; bacteria) 9 Pepsin (protein digestion) 9 Gastric lipase (Lipids) 9 Gastrin (stimulate gastric secretion and movement) 4 Secretions of Digestive Tract Digestive Tract Small intestine: ¾ Duodenum (25 – 30 cm) ¾ Jejunum (120 cm) ¾ Ileum (150 cm) Assisting Organs: Liver & gallbladder Pancreas Secretions of Digestive Tract Assisting Organs Pancreas – Pancreatic juice Enzymes (trypsin, amylase, lipase, chymotrypsin) bicarbonate Secretions of Digestive Tract Assisting Organs Liver – Bile Emulsifier Gallbladder 5 Muscular Action of Digestive Tract Peristalsis Peristalsis Segmentation Muscular Action of Digestive Tract - Segmentation Digestive Tract Large intestine = colon – Ileocecal valve – Appendix Rectum – Anus 6 The Final Stage Colon Fermentation of undigested residues (bacteria; vitamins K, B12, thiamin, riboflavin, biotin, other B’ B’s; gases; Short chain fatty acids; antibiotics protectants) protectants) Stool Copyright 2005 Wadsworth Group, a division of Thomson Learning Copyright 2005 Wadsworth Group, a division of Thomson Learning Digestion of a Sandwich Digestion of a Sandwich 7 Digestive Tract Absorption – Modes of Transportation Small intestine: ¾ Duodenum (25 – 30 cm) ¾ Jejunum (120 cm) ¾ Ileum (150 cm) Assisting Organs: Liver & gallbladder Pancreas Absorption in the Small Intestine The Small Intestinal Villi Villi – Microvilli – Capillaries and lacteals – Chylomicrons Crypts 8 The Small Intestinal Villi, cont’ cont’d Circulatory Systems Vascular system – Heart – Arteries – Capillaries – Veins Circulatory Systems Vascular system – Portal vein – Hepatic vein 9 The Liver Circulatory Systems Lymphatic system – Lymph – Thoracic duct Subclavian vein 10