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Anaesthesia for Obstetric Surgical Procedures September 2010 Retained placenta • Sensory block to T10 required • Spinal/existing epidural • Patient potentially hypovolaemic Repair of perineal tear • Spinal/existing epidural • Good quality saddle block required • Potentially hypovolaemic patient Anaesthesia for Cervical Suture • 1st/2nd trimester • Spinal/GA • If GA – Avoid prolonged exposure to nitrous oxide • Potentially teratogenic in first trimester – Avoid hypotension/hypercarbia – fetal acidosis Introduction • NHS maternity statistics 2008-09: UK c/section rate = 24.6% • RJMH c/section rate = 36.2% • NOAD 2007: anaesthesia for c/section – Spinal – 59.6% – Epidural top-up – 22.1% – GA – 10.1% – CSE – 7.2% – De novo epidural – 0.8% RCOA Audit Standards • • • • Elective c/section > 95% RA Emergency c/section> 85% RA Elective c/section <1% RA to GA Emergency c/section < 3% RA to GA Elective c/section • Common indications: – Maternal request! – Breech presentation – Previous c/section – Placenta praevia – Significant medical conditions Choice of Anaesthetic • Patients preference • Patients physical profile, health considerations, pregnancy factors • Anticipated surgical difficulties • Experience and speed of surgeon Preparation for Anaesthesia • • • • Preop assessment Informed consent Antacid prophylaxis Fully prepared anaesthetic room/theatre – – – – Checked anaesthetic machine Monitoring equipment Tilting operating table Resuscitation equipment • Trained anaesthetic assistant • Large bore I.V. access Spinal Anaesthesia • Used >90% elective LSCS • Incidence of PDPH approx 1:400 due to small gauge PP needles • Technically simple • Consistent, dense quality of block • Failure rate approx 1% Spinal Anaesthesia • Standard technique – PP needle, no larger than 25G to minimise PDPH risk – Injection at, or below L3/L4 interspace to avoid damage to conus – Diamorphine 300mcg – Injection performed in sitting position, then moved immediately to L tilted supine position on completion – Phenylephrine ivi to prevent hypotension Spinal Anaesthesia • Hyperbaric Bupivicaine 0.5% - most used LA in UK • Recommended doses vary • Surgery requires sensory blockade to T4 • Patient factors influencing dose – Height – Abdominal size Intrathecal Opiates • Fentanyl – Highly lipid soluble – Reduced intraop discomfort – Provides no post op analgesia • Morphine – Long duration of action – Little intraop effect due to poor lipophillicity • Diamorphine – Rapid onset – Long duration of action • Side Effects: – PONV approx 30% – Pruritus Spinal induced hypotension • Can cause fetal distress • Symptoms: dizziness, N&V • Should be treated aggressively – Approp positioning – Fluid preloading – Use of Phenylephrine ivi • Titrated to maternal BP • Higher fetal pH than Ephedrine Spinal after epidural • Technique most likely to lead to high/total spinal anaesthesia. ? Dural sac compression by epidural fluid • No formula for reducing spinal dose. NB inadequate block • Precautions – – – – – Warn patient of risk of conversion to GA Assess airway Perform spinal in approp environment Reduction of spinal dose Consider leaving epidural catheter in situ Epidural ‘top-up’ • Category 2 LSCS with epidural in situ • Slow onset anaesthesia • Inferior anaesthesia to spinal during surgery • L-Bupivicaine 0.5%; Ropivicaine 0.75%; supplemental Diamorphine. CSE • 3 approaches 1. ‘Full’ dose spinal with epidural back up if inadequate block height/duration 2. Reduced dose spinal with supplemental epidural top-ups 3. Epidural volume extension-low dose spinal extended by dural sac compression using epidural saline • • ‘Needle through needle’ Separate needle, separate interspace CSE 1. Used to reduce incidence of spinal failure – Tall patients – IUGR – Prolonged surgery 2. Reduces haemodynamic changes by more gradual onset anaesthesia; reduced risk of excessive block height – Cardiac patients – Short patients 3. Short duration of blockade esp motor blockade Continuous Spinal • • • • • Niche role ‘Difficult’ equipment PDPH Careful titration of dose Haemodynamic stability – Cardiac disease – Extremely small stature – Severe skeletal deformity • Extended period of anaesthesia Pain during LSCS • Leading cause of litigation – Closed claims analysis 1995-2007 • Pain during surgery - 31% (57) • Informed consent • Give adequate doses of drugs including opioid • Produce and document adequate sensory and motor block • Management – Alfentanil 250mcg iv – Entonox • Conversion to GA – NB. Clear documentation of management esp if patient refuses GA GA • Indications – Refusal of RA – Contraindications eg. Coagulopathy – Insufficient time to establish RA – Serious haemorrhage anticipated – Failed RA GA • Reliable and safe if – Aspiration prophylaxis – Trained anaesthetic assistance – Meticulous pre-oxygenation – Well rehearsed failed intubation drill – Approp drug regimen to reduce incidence of awareness – Awake extubation Drugs used for GA • RSI with cricoid pressure • Thiopentone/Propofol? – Propofol • Poorer neonatal profile • Shorter duration of amnesia • Longer time to recovery of spontaneous ventilation • Suxamethonium/Rocuronium? – Inadequate doses assoc with difficult intubations • NB 1.5mg/kg; Increased Vd – Prolonged action of Rocuronium • NB. Sugammadex Perioperative Drugs • Opiates at induction and post op analgesia • On delivery of neonate – Syntocinon 5IU and IVI – Prophylactic antibiotics • Thromboprophylaxis Complications • Failed intubation (1 in 300) – – – – – – – • • • • Increased fatty tissue Complete dentition Increased pharnygeal and laryngeal oedema Incorrect drug dosages Large tongue Large breasts Increasing obesity Aspiration (1 in 400-600) Awareness Increased intaop blood loss PONV Post op pain relief • Introp: – Diclofenac 100mg PR – Intrathecal Diamorphine – IV Morphine and TAP blocks • Post op: – Diclofenac 50mg PO TID – Paracetamol 1g PO QID – Codeine 30-60mg PO QID Emergency LSCS • • • • • • Grades of urgency – category 1 to 4 Nationally accepted classification ‘Continuum of risk’ Facilitates audit Improves multidisciplinary communication Individual, ‘case by case’ approach to decision to delivery interval Emergency LSCS • Category 1 & 2 • In utero fetal resuscitation – – – – – – Syntocinon off Position full L lateral Oxygen I.V fluids Low BP – vasopressors Tocolysis: GTN 400mcg/B2 agonist • Choice of anaesthesia • Post op analgesia • Post op care