Download Things to Consider? Side Effects? Cost? How Soon? How Often

Things to Consider?
How Often?
What is important to you
about arthritis medicines?
Side Effects?
How Soon?
Cost?
2013, Cincinnati Children’s Hospital Medical Center. All Rights Reserved.
©
This work is taken from or based upon information and data from sites contributing to the Pediatric Rheumatology –
Care and Outcomes Improvement Network (PR-COIN) www.pr-coin.org and may not be used for commercial purposes.
How Long?
Things to Consider?
®
Medications
require blood
test monitoring.
Pick another topic
Sulfasalazine
®
)
(Arava®)
While taking
these medicines
you should...
: not become
pregnant
: not drink alcohol
: not receive live
vaccines
Updated 3.29.13
Avoid these
medicines if you...
: have liver disease
: have TB (you may
need to be tested)
)
®
Etanercept
(Enbrel®)
Adalimumab
(Humira®)
Anakinra
(Kineret®)
Abatacept
(Orencia®)
(Remicade®)
®
2013, Cincinnati Children’s Hospital Medical Center. All Rights Reserved.
©
This work is taken from or based upon information and data from sites contributing to the Pediatric Rheumatology –
Care and Outcomes Improvement Network (PR-COIN) www.pr-coin.org and may not be used for commercial purposes.
)
Canakinumab
(Ilaris®)
Tocilizumab
(Actemra®)
on how often they
need to be given.
1x
Updated 3.29.13
Sulfasalazine
®
)
(Arava®)
2x
!"#$%
day
!"#$%
day
)
®
1x
®
!"#$%
week
Etanercept
(Enbrel®)
How Often?
1-2x
!"#$%
week
!"#$%
month
Pick another topic
2-4x
!"#$%
month
Abatacept
(Orencia®)
1x
Adalimumab
(Humira®)
Anakinra
(Kineret®)
1x
day
(Remicade®)
1x
month
2013, Cincinnati Children’s Hospital Medical Center. All Rights Reserved.
©
This work is taken from or based upon information and data from sites contributing to the Pediatric Rheumatology –
Care and Outcomes Improvement Network (PR-COIN) www.pr-coin.org and may not be used for commercial purposes.
!"#$%
!"#$%
)
1 month every
6 months
1x
!"#$%
month
®
2x in
Canakinumab
(Ilaris®)
!"#$%
Tocilizumab
(Actemra®)
1-2x
month
!"#$%
(Arava®)
you will experience.
Sulfasalazine
®
)
)
Side Effects?
®
Anakinra
(Kineret®)
Adalimumab
(Humira®)
Canakinumab
(Ilaris®)
Abatacept
(Orencia®)
Pick another topic
•
•
•
•
stomach upset
diarrhea
headache
cold symptoms
• low blood counts
• severe liver injury
•
•
•
•
mouth sores
nausea
stomach upset
headache
• severe skin reaction
(Sulfasalazine only)
• abnormal liver test
• low blood counts
•
®
Etanercept
(Enbrel®)
(Remicade®)
Uncommon:
)
®
• redness or soreness
where needle enters skin
• common cold
• sinus infection
• stomach upset
• headache
• itchy or allergic rash
• TB may come back
• serious infection that
needs antibiotic
• low blood counts
• development of
autoantibodies
•
• cancers like lymphoma
•
•
•
•
• TB may come back
• serious infection that
needs antibiotic
• low blood counts
• development of
autoantibodies
• cancers like
lymphoma
• severe infusion
reaction (allergic
reaction)
common cold
sinus or throat infection
stomach upset
headache
Tocilizumab
(Actemra®)
2013, Cincinnati Children’s Hospital Medical Center. All Rights Reserved.
©
This work is taken from or based upon information and data from sites contributing to the Pediatric Rheumatology –
Care and Outcomes Improvement Network (PR-COIN) www.pr-coin.org and may not be used for commercial purposes.
Updated 3.29.13
There is no way to
predict which, if any,
Common:
In general, these
medicines begin
to work between
2 and 12 weeks.
(Arava®)
Sulfasalazine
®
)
4-8
4-12
weeks
®
weeks
)
®
4-6
There are ways
to manage symptoms
until these medicines
start working.
How Soon?
weeks
Etanercept
(Enbrel®)
Adalimumab
(Humira®)
Anakinra
(Kineret®)
Canakinumab
(Ilaris®)
2-4
2-4
1-3
1-3
weeks
weeks
Abatacept
(Orencia®)
(Remicade®)
2-12
2-4
weeks
Pick another topic
Updated 3.29.13
These medicines do
not work right away.
weeks
2013, Cincinnati Children’s Hospital Medical Center. All Rights Reserved.
©
This work is taken from or based upon information and data from sites contributing to the Pediatric Rheumatology –
Care and Outcomes Improvement Network (PR-COIN) www.pr-coin.org and may not be used for commercial purposes.
weeks
)
®
2-4
weeks
weeks
Tocilizumab
(Actemra®)
2-4
weeks
Updated 3.29.13
What you pay will
depend on your
insurance.
Sulfasalazine
®
)
(Arava®)
$
Patient assistance
programs may
be available.
®
)
®
$
Etanercept
(Enbrel®)
Adalimumab
(Humira®)
Anakinra
(Kineret®)
Canakinumab
(Ilaris®)
$$
Cost?
Abatacept
(Orencia®)
(Remicade®)
)
®
$$$
Pick another topic
2013, Cincinnati Children’s Hospital Medical Center. All Rights Reserved.
©
This work is taken from or based upon information and data from sites contributing to the Pediatric Rheumatology –
Care and Outcomes Improvement Network (PR-COIN) www.pr-coin.org and may not be used for commercial purposes.
Tocilizumab
(Actemra®)
Updated 3.29.13
Stopping or
decreasing the
medicine may be
considered after
the disease is
well controlled.
•
•
•
How often does arthritis remain well controlled
after stopping?
What are the treatment options if the arthritis comes
How Long?
•
How long has the disease been under control?
Pick another topic
2013, Cincinnati Children’s Hospital Medical Center. All Rights Reserved.
©
This work is taken from or based upon information and data from sites contributing to the Pediatric Rheumatology –
Care and Outcomes Improvement Network (PR-COIN) www.pr-coin.org and may not be used for commercial purposes.