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1 STI CLINICAL SCIENCE PRESENTATIONS – WORLD TRANSPLANT CONGRESS 2006 ORAL PRESENTATIONS PRESENTER Geoffrey Bond TITLE Is Histadine-Trypophan-Ketoglutarate (HTK) a better cold preservative solution for intestinal and multivisceral allografts Geoffrey Bond Kidney transplantation en-bloc with liver and multivisceral organs in patients with insufficient venous access: A technical challenge Michael DeVera Tacrolimus alone and predisone-free immunosuppression (IS) without the use of induction therapy in adult liver transplant (LTx) recipients Michael DeVera The impact of recurrent Hepatitis C after liver transplantation (LTx) in HIV and HCV coinfected patients Igor Dvorchik Maureen Emerling Csaba Galambos Alin Girnita Diana Girnita Shahid Habib SESSION DATE AND TIME Oral Preservation: Clinical I July 24, 2006; 11:10 am Publication #65 Kidney Clinical: Surgical Issues July 27, 2006; 12:10 pm Publication #1144 Evolving Methods of Immunosupression in Liver Transplantation July 25, 2006; 10:50 am Publication #485 The Challenge of Hepatitis B and C in Transplantation July 26, 2006; 5:50 pm Publication #951 Staging system for hepatocellular carcinoma Transplant Associated (HCC) based on fractional allelic loss Malignancy: Clinical Investigations July 26, 2006; 10:40 am Publication #772 Psychosocial rehabilitation after intestinal and Ethics and Quality of Life multivisceral transplantation July 27, 2006; 11:30 am Publication #1188 Characterization of C4d immunostain utilizing Pediatric Heart, Lung, Intestine paraffin-embedded tissue of non-presensitized and Other Transplantation pediatric cardiac transplant patients July 25, 2006; 11:00 am Publication #437 Increased detection of donor specific anti-HLA HLA Antibodies Impact Post antibodies after lung allograft removal Transplantation July 25, 2006; 5:10 PM Publication #526 Gene polymorphism frequency distribution among Pediatric Heart, Lung, Intestine ethnic groups may contribute to disparate clinical and Other Transplantation outcomes in pediatric heart transplantation July 25, 2006; 10:30 am Publication #434 *Top 10% of abstracts selected for oral presentation Use of the Model for End-Stage Liver Disease (MELD) score to predict survival benefit of liver transplantation in patients with cirrhosis Risk Factors Contributing to Outcome in Liver Transplant Recipients July 24, 2006; 10:50 am Publication #87 2 Camila Macedo Characterization of EBV-specific CD8+ T cells in pediatric heart transplant patients EBV and New Viral Pathogens in Transplantation July 24, 2006; 4:10 pm Publication #242 Diana Metes DC subsets in peripheral blood of lung transplant recipients pre-conditioned with Campath-1H Lung Transplantation Ex vivo generation of EBV-specific CTLs using peptide pulsed DC1 from solid organ transplant recipients results in expansion of CD8+ Type-1 like-regulatory (IFN- and IL-10) Foxp3+ T cells PTLD and Transplant Associated Malignancy: Basic Investigations Efficient ex-vivo generation of EBV-specific T cell from peripheral cell from peripheral blood of EBV-seronegative heart transplant patients PTLD and Transplant Associated Malignancy: Basic Investigations Early intestinal transplantation for patients with acute irreversible intestinal failure Intestinal Transplantation Iulia Popescu Iulia Popescu Bonnie Schuster Ron Shapiro *Top 10% of abstracts selected for oral presentation Alemtuzumab preconditioning and tacrolimus monotherapy in adult kidney transplants recipients July 25, 2006; 5:20 pm Publication #623 July 25, 2006; 10:30 am Publication #410 July 25, 2006; 11:20 am Publication #415 July 25, 2006; 4:00 pm Publication #627 Antibody Therapy July 25, 2006; 5:10 pm Publication #670 Approaches to Tolerance in the Clinic July 24, 2006; 5:40 pm Publication #311 Rakesh Sindhi Transmission disequilibrium of 2300mMHC-wide SNP-preliminary outcome associations in tolerant and immunosuppressed pediatric liver recipients Rakesh Sindhi Distinct patterns of donor-specific proliferation in T-Cell subsets among immunosuppressed and tolerant pediatric liver/intestine recipients Pediatric Heart, Lung, Intestine and Other Transplantation Steroid-free pediatric intestinal transplantationFour-year experience in 75 children Intestinal Transplantation Sustained survival and growth advantages of steroid-free intestinal transplantation at 2-year follow-up Living donor liver transplantation with alemtuzumab induction and steroid free tacrolimus monotherapy Intestinal Transplantation Rakesh Sindhi Rakesh Sindhi Henkie Tan July 25, 2006; 11:30 am Publication #440 July 25, 2006; 4:30 pm Publication #630 July 25, 2006; 5:30 pm Publication #636 Evolving Methods of Immunosuppression in Liver Transplantation July 25, 2006; 11:10 am Publication #487 Ngoc Thai Pancreas transplantation under Campath-1H and tacrolimus: correlation between low T Cell responses and infection Advances in Simultaneous Pancreas-Kidney Transplantation July 24, 2006; 11:10 am Publication #113 3 Jian Wang Adriana Zeevi Novel gene polymorphisms in the Impdh2 gene may account for neutropenia and other side effects in patients treated with mycophenolic acid (Mpa) Recovery of functional memory T cells in lung transplant recipients on induction therapy Genetic Engineering, Genomics, Proteomics July 27, 2006; 11:30 am Publication #1054 Lung Transplantation July 25, 2006; 5:10 pm Publication #622 POSTER PRESENTATIONS PRESENTER Michael Bingler Geoffrey Bond Geoffrey Bond Diana Girnita TITLE Kinetics of primary EBV infection after pediatric heart transplantation SESSION DATE AND TIME EBV and Opportunistic Infections The role of intestinal reconstruction and rehabilitation in an intestinal transplant center Intestinal Transplant Biliary complications after composite visceral transplantation with preservation of the donor duodenum The HLA compatibility in pediatric heart transplant recipients is better assessed by analysis at amino acid residue level Intestinal Transplant Shahid Husain Infection profile in lung transplant recipients associated with suppressed T cell reactivity Shahid Husain Prospective assessment of the Platelia aspergillus EIA in the bronchoalveolar lavage fluid for the early diagnosis of invasive aspergillosis (IA) in lung transplant recipients Beverly KosmachPark Successful pregnancy following intestine transplantation in a long-term survivor Beverly KosmachPark Improved developmental outcomes following pediatric intestine transplantation (ITx) Karen Laughlin The efficacy of intravenous immune globulin (IVIG) in small bowel and multivisceral allografts transplanted across a positive lymphocytotoxic crossmatch Laura Matarese Weight gain and obesity after intestinal transplantation July 27. 2006; 12:30 – 2:00 pm Publication #2737; Board #? July 26, 2006; 12:30 – 2:00 pm Publication #2380; Board #? July 26, 2006; 12:30 – 2:00 pm Publication #2381; Board #? Pediatric Heart, Lung, Intestine and other Transplantation July 25, 2006; 12:30 – 2:00 pm Publication #2004; Board #331 Immune Profiling and Molecular Monitoring July 25, 2006; 12:30 – 2:00 pm Publication #1893; Board #220 EBV and Opportunistic Infections July 27, 2006; 12:30 – 2:00 pm Publication #2741; Board #159 Intestinal Transplant July 26, 2006; 12:30 – 2:00 pm Publication #2391; Board #266 Intestinal Transplant July 26, 2006; 12:30 – 2:00 pm Publication #2390; Board #265 Histocompatibility and Sensitization July 26, 2006; 12:30 – 2:00 pm Publication #2140, Board #15 Intestinal Transplant July 26, 2006; 12:30 – 2:30 pm Publication #2386; Board #261 4 Margaret Reidy Physical and occupational rehabilitation after intestinal transplantation Lynn Seward Abdominal transplant acuity scoring system Ron Shapiro Alemtuzumab preconditioning and tacrolimus monotherapy in pediatric kidney transplant recipients June Stamos Intestinal and multivisceral transplantation for patients with abdominal malignancy: Disease recurrence and survival outcome Henkie Tan Living donor hepatectomies: Program experience and lessons learned Henkie Tan Living donor renal transplantation with alemtuzumab induction and steroid-free tacrolimus monotherapy Henkie Tan Preservation fluid using heparinized lactated Ringers with procaine in living donor kidney transplantation Ethics July 24, 2006; 12:30 – 2:00 pm Publication #1583; Board #378 Ethics July 24, 2006; 12:30 – 2:00 pm Publication #1582; Board #377 Kidney Transplantation: Rejection and Immunosuppression July 24, 2006; 12:30 – 2:00 pm Publication #1261; Board #56 Intestinal Transplant July 26, 2006; 12:30 – 2:00 pm Publication #2379; Board #254 Living Donor Liver Transplantation I July 25, 2006; 12:30 – 2:00 pm Publication #1925; Board #252 Kidney Transplantation: Clinical I July 26, 2006; 12:30 – 2:00 pm Publication #2208; Board #83 Organ Preservation: Clinical July 27, 2006; 12:30 – 2:00 pm Publication #2597; Board #15 INVITED PRESENTATIONS PRESENTER Kareem Abu-Elmagd Beverly KosmachPark Amadeo Marcos TITLE Chronic allograft rejection: Diagnosis, risk factors and outcome Are you a pediatric patient forever? Transitioning adolescents to adult transplantation programs Controversies in transplantation for patients with malignancy SESSION DATE AND TIME Intestinal Transplantation July 26, 2006; 2:30 pm Postgraduate Course – Associate Transplant Professional Symposium July 22, 2006; 10:50-11:20 am Surgical Limits and Challenges: Panel Discussions July 23, 2006; 10:30-12:00 pm Prevention and management of thrombosis Transplantation in the poor risk candidate Management of catastrophic events Ron Shapiro Medical management of BK viremia vs. BK nephropathy Postgraduate Course Clinical Transplant Update July 22, 2006; 2:30 pm 5 Steve Webber Specific treatment if reduction in immunosuppression ineffective Adriana Zeevi The impact of new technology for antibody detection on risk assessment in renal and nonrenal transplantation State-of-the-Art-Symposium PTLD in Pediatric Transplantation July 25, 2006; 2:40 pm Premeeting Symposium Alloimmunization: Risk Assessment and Avoidance of a Detrimental Effect in Clinical Transplantation July 23, 2006; 8:30 am SESSION CO-CHAIR CO-CHAIR Amadeo Marcos SESSION TITLE Living Donor Issues in Liver Transplantation SESSION DATE AND TIME State of the Art Symposia July 26, 2006; 2:00-3:30 pm AWARD AST Roche Ernest Hodge Memorial Award CEREMONY DATE AND TIME AWARDS RECIPIENT Thomas Starzl July 25, 2006; 9:55 – 10:15 am