Download Cijo George Vazhappilly, Ph.D.

CURRICULUM VITAE
Cijo George Vazhappilly, Ph.D.
Post Doctoral Research Fellow
Sharjah institute for Medical Research
University of Sharjah
Sharjah, UAE
Email: [email protected]
Tel (Mobile): 0588204879
Nationality : Indian
Date of Birth : March 3, 1986
EDUCATION:
UNIVERSITY AND LOCATION
DEGREE
YEAR
SPECILIZATION
VIT University, Vellore, India
Ph.D.
2014
Cancer Biology
Bharathiar University, Coimbatore, India
M.S.
2009
Biotechnology
Bangalore University, Bangalore, India
B.S.
2007
Biotechnology
POST‐DOCTORAL TRAINING:
POSITION
UNIVERSITY
LOCATION
FROM
TO
Post-doctoral
Research Associate
Sharjah institute for Medical Research
UAE
Nov 2016
Present
Dalhousie University
Canada
Nov 2015
Nov 2016
The University of Texas
USA
May 2014
May 2015
Cochin University of Science &
Technology
India
Dec 2013
April 2014
Post-doctoral
Fellow
Post-doctoral
Research Associate
DBT-Research
Associate
OTHER APPOINTMENTS:
 CSIR-Senior Research Fellow (SRF) at VIT University, Vellore, Tamil Nadu, India, April
2013-December 2013.
 Research Associate at VIT University, Vellore, Tamil Nadu, India, July 2010- March 2013.
 Technical Project Assistant at Kerala Forest Research Institute (KFRI), Peechi, Thrissur, India,
June 2009 – Nov 2009.
 Research Fellow at Rajiv Gandhi Center for Biotechnology (RGCB), Trivandram, India,
December 2008-May 2009.
AWARDS:
 Mitacs Accelerate- Post Doctoral internship by Mitacs, Canada, 2016.
 SERB-National Post Doctoral Fellowship by Department of Science and Technology (DST), India,
2016.
 CSIR-SRF fellowship for Doctorial research (Ph.D.) by Council of Scientific and Industrial Research
(CSIR) organization, New Delhi, India in 2013.
 Second prize for the research poster entitled “Isolation and detection methods of tumor cell linederived exosomes- “garbage of bin/hidden treasures”-assay standardization for a better
comprehension of cell type-specific apoptotic phenomena” presented in Medical Hackathon
“CAMTech- India Medical Hackathon” organized by the “The International Consortium of Affordable
Medical Technologies- CAMTech on Nov, 26,2012 at VIT University, India.
FUNDED PROJECT:
 Cijo George Vazhappilly (PI). Isolation, characterization and validation of bioactive compounds
from Annona muricata for their in vitro selective role in cervical tumor inhibition, Funded by
DST-SERB, India, 2016.
PUBLICATIONS:
1) V. Cijo George, Graham Dellaire and H.P. Vasantha Rupasinghe. Plant flavonoids in cancer
chemoprevention: Role in genome stability. The Journal of Nutritional Biochemistry, 2017, 45:114.
2) V. Cijo George*, V. V. Vijesh,…………..and H.P. Vasantha Rupasinghe. Mechanism of action of
flavonoids in prevention of inflammation-associated skin cancer. Current Medicinal Chemistry,
2016, 23: 3697-3716.
3) V. Cijo George*. Promising tumor inhibiting potentials of Fisetin through PI3K/AKT/mTOR
pathway. American Journal of Translational Research, 2016; 8: 1293-1294.
4) V. Cijo George, D. R. Naveen Kumar and R. Ashok kumar. Relative in vitro potentials of
parthenolide to induce apoptosis and cell cycle arrest in skin cancer cells. Current Drugs Discovery
Technologies, 2016; 13: 34-40.
5) V. Cijo George*. Plant polyphenols can protect VEGF-induced vascular leakage ?. EXCLI, 2016,
15; 153-154.
6) V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. Luteolin induces caspase14 mediated terminal differentiation in human epidermal keratinocytes, In Vitro Cellular &
Developmental Biology-Animal, 2015, 51:1072-1076.
7) V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. In vitro protective
potentials of Annona muricata leaf extracts against sodium arsenite-induced toxicity, Current Drugs
Discovery Technologies, 2015, 12:59-63.
8) D. R. Naveen kumar, V. Cijo George, P. K. Suresh and R. Ashok Kumar. Cancer-specific
chemoprevention and anti-metastatic potentials of Rheum emodi rhizome ethyl acetate extracts and
identification of active principles through HPLC and GC-MS analysis. Pakistan Journal of
Pharmaceutical Science, 2015; 28:83-93.
9) V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. Antioxidant, DNA
protective efficacy and HPLC analysis of Annona muricata (soursop) extracts. Journal of Food
Science and Technology, 2014; 52:2328-2335.
10) V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. Oleanolic acid inhibits cell
growth and induces apoptosis in A375 melanoma cells. Biomedicine & Preventive Nutrition, 2014;
4:95-99.
11) V. Cijo George, D. R. Naveen Kumar, P. K. Suresh, Sanjay Kumar and R. Ashok kumar.
Comparative studies to evaluate in vitro relative potency of luteolin in inducing cell cycle arrest and
apoptosis in HaCaT and A375 cells. Asian Pacific Journal of Cancer Prevention, 2013; 14: 631637.
12) D. R. Naveen Kumar, V. Cijo George, P. K. Suresh and R. Ashok kumar. Acceleration of Procaspase-3 maturation and anti-metastasis in human breast cancer cells by phytoconstituents of Rheum
emodi rhizome extracts. EXCLI Journal, 2013;12: 462-478.
13) D. R. Naveen kumar, V. Cijo George, P. K. Suresh and R. Ashok Kumar. Demonstration of
differential anti-neoplastic potentials of Oroxylum indicium ethyl acetate extracts in human breast
cancer cells. Journal of Biological Sciences, 2013;13: 534-539.
14) V. Cijo George, D. R. Naveen Kumar, P. K. Suresh, R. Ashok Kumar. Apoptosis-induced cell death
by Oleanolic acid in HaCaT keratinocyte cells; a proof-of-principle approach for chemopreventive
drug development. Asian Pacific Journal of Cancer Prevention, 2012;13: 2015-2020
15) V. Cijo George, D. R. Naveen Kumar, V. Rajkumar, P. K. Suresh and R. Ashok kumar. Quantitative
assessment of the relative antineoplastic potential of the n-butanolic leaf extract of Annona muricata
Linn. in normal and immortalized human cell lines. Asian Pacific Journal of Cancer Prevention,
2012;13: 699-704.
16) D. R. Naveen kumar, V. Cijo George, P. K. Suresh and R. Ashok Kumar. Apoptosis-mediated
cytotoxicity and anti-metastatic potential of Oroxylumindicum in human breast cancer cells. Asian
Pacific Journal of Cancer Prevention, 2012;3: 2729-2734.
17) V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. A review on therapeutic
potentials of parthenolide: A sesquiterpene lactone”. International Research Journal of Pharmacy,
2012;3: 69-73.
18) D. R. Naveen kumar, Swati Shikha, V. Cijo George, P. K. Suresh and R. Ashok Kumar. Anticancer
and anti-metastatic activities of Rheum emodi rhizome chloroform extracts. Asian Journal of
Pharmaceutical and Clinical Research, 2012;5: 189-194.
19) D. R. Naveen Kumar, V. Cijo George, V. Rajkumar and R. Ashok Kumar. Cytoprotective effect of ()-Epigallocatechin [EGC] against Chlorpyriphos-induced cytotoxicity, Journal of Pharmacy
Research, 2011;4: 1743-1744.
 Abstracts in Journals:
1. V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. Luteolin induces the
expression of caspase-14 in a prototypical human immortal keratinocytes (HaCaT) cell line -an
important protein in the continuum of events from proliferation to terminal differentiation. In Vitro
Cellular & Developmental Biology-Animal, 2013;49: 562-562.Doi 10.1007/s11626-013-9652-y.
2. V. Cijo George, D. R. Naveen Kumar, P. K. Suresh, R. Ashok Kumar. Evaluating betulinic acid for
terminal differentiation inducing potentials in skin cancer cells – a promising approach in
chemotherapeutic drug development. Journal of Carcinogenesis, 2012;11:(Supplement 1) S27.
3. D. R. Naveen kumar, V. Cijo George, P. K. Suresh and R. Ashok Kumar. Systematic studies to
evaluate caspase-3-mediated cell death in estrogen recptor-negative breast cancer cells by bark
extracts of Oroxylum indicum. Journal of carcinogenesis, 2012;11: (Supplement 1) S36.
 Scientific Meeting Abstracts:
1
V. Cijo George and H.P. Vasantha Rupasinghe. Podium presentation in Beatrice Hunter Cancer
Research Institute (BHCRI) conference, Nov 2016. Halifax, Canada.
2
V. Cijo George and H.P. Vasantha Rupasinghe, Poster Presented in International conference on
Cancer Immunotherapy (Summit4CI), June 2016. Halifax, Canada.
3
V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. Oral Presentation in
International Conference on Stem Cells and Cancer (ICSCC-2012), October 2012. New Delhi, India.
4
V. Cijo George, D. R. Naveen Kumar, P. K. Suresh and R. Ashok kumar. Poster Presented in
International conference on Molecular Medicine, (MOLMED,2012), February 2012. Vellore, India.
5
V. Cijo George, D. R. Naveen Kumar, V. Rajkumar, P. K. Suresh and R. Ashok kumar: Poster
Presented in international conference on Environment Genes Health and Disease, (EGHD,2011),
December 2011. Coimbatore, India.
TEACHING EXPERIENCE:

Experience of supervising & teaching graduate students (Pharmacology & Biochemistry) for 1
year
REVIEWER AND MEMBER:
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Cancer letters
Scientific reports
Phototherapy Research
Apoptosis
DST-SERB, India
Inflammopharmacology
Austin journal of dermatology (Editorial Member)