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ACTC 2017 PRELIMINARY PROGRAM
DAY 1: Wednesday October 4
Time
7:30 – 8:30
8:30 – 9:00
9:00 – 9:30
PL1-1
9:30 – 10:00
PL1-2
10:00 – 10:30
PL1-3
Session/Title
Wednesday October 4
Confirmed Speaker
Registration
Welcome address
Chairperson’s Opening Remarks
Plenary Lecture Session 1:
Recent Advances in the biology of metastasis
9:00 – 12:30
“Liquid Biopsy: Potential and Challenges”
Klaus Pantel, Professor, Director, Institute of Tumour
Biology, Centre of Experimental Medicine, University
Medical Centre Hamburg Eppendorf, Hamburg, Germany
“title to be announced”
Jean Paul Thiery, Professor, Research Director
Comprehensive Cancer Center Institut Gustave Roussy,
Villejuif, France
“The forgotten genome: Surprising roles of mitochondria
in cancer metastasis”
Danny R. Welch, Professor & Chair, Department of Cancer
Biology, KU Cancer Center, Kansas, USA
10:30 – 11:00
Networking Coffee Break in the Exhibition Hall
11:00 – 11:30
PL1-4
“Molecular analysis of circulating breast cancer stem
cells”
Max S. Wicha, M.D. Madeline and Sidney Forbes Professor
of Oncology, Director, Forbes Institute for Cancer Discovery
Founding Director Emeritus, University of Michigan
Comprehensive Cancer Center , Ann Arbor, USA
“Bone niches for the development and treatment
resistance of skeletal metastasis”
Yibin Kang, PhD, Warner-Lambert/Parke-Davis Professor of
Molecular Biology, Princeton University, Princeton, New
Jersey, USA
"The role of the DNA damage response pathway (DDR) in
cancer: beneficial and adverse effects"
Vassilis Gorgoulis, Professor, Lab Histology-Embryology,
Medical School, National and Kapodistrian University of
Athens; Biomedical Research Foundation of the Academy of
Athens, Greece; Honorary Professor, Faculty of Biology,
Medicine and Health, University of Manchester.
11:30 – 12:00
PL1-5
12:00 – 12:30
PL1-6
12:30 – 14:00
Lunch Break
14:00 – 15:00
POSTER SESSION 1: Recent Advances in the biology of
metastasis
1
And networking coffee break in the Exhibition Hall
15:00 – 18:30
Plenary Lecture Session 2:
Liquid Biopsy in breast cancer: The clinician’s point of view
15:00 – 15:30
PL2-1
15:30 – 16:00
PL2-2
16:00 – 16:30
PL2-3
16:30 – 17:00
17:00 – 17:30
PL2-4
17:30 – 18:00
PL2-5
18:00 – 18:30
PL2-6
“Recent clinical data on DTCs and CTCs in breast cancer”
Bjorn Naume, Professor, Oslo University Hospital, Oslo,
Norway
“CTCs and circulating miRNAs in early breast cancer”
Sofia Agelaki, MD, PhD, Ass. Professor, Medical School,
University of Crete, Greece
“Liquid biopsy for drug development in breast cancer”
Michail Ignatiadis, Ass. Professor, Jules Bordet Institute,
Brussels, Belgium
networking coffee break in the Exhibition Hall
“The fluid revolution: The evolution of CTCs research”
Massimo Cristofanilli, MD, FACP, Associate Director for
Precision Medicine and Translational Research, Lurie Cancer
Center, Northwestern University, Chicago, USA
"Clinical utility of CTC and ctDNA in metastatic and
neoadjvuant setting of breast cancer”
Jean-Yves Pierga, MD, PhD, Professor of Medical Oncology,
at the Institute Curie and University Paris Descartes, Paris,
France
“CTCs in the neo-/adjuvant setting: is therapeutic
monitoring in primary breast cancer possible after all?”
Wolfgang Janni, Professor and Chair of Department of
Obstetrics and Gynecology, University of Ulm, Germany
18:30 – 22:00
WELCOME RECEPTION
2
DAY 2: Thursday, October 5
Time
8:30 – 9:00
PL3-1
9.00 – 9.30
PL3-2
9:30 – 10:00
PL3-3
10:00 – 10:30
PL3-4
Session/Title
Confirmed Speaker
Thursday, October 5
8:30 – 12:30
Plenary Lecture Session 3:
Liquid Biopsy in solid cancers
What’s next for lung cancer CTCs?
Caroline Dive, PhD, Professor, Deputy Director Cancer
Research UK Manchester Institute, Senior Group Leader
Clinical & Experimental Pharmacology, The University of
Manchester, UK
“Molecular and functional characterization of CTCs in
non-small cell lung cancer”
Francoise Farace, PhD, Gustave Roussy, Université ParisSaclay , "Circulating Tumor Cells" Translational Platform,
CNRS, France.
“Recent advances in Circulating Tumor Cells in Prostate
cancer”
H. Scher, MD, Medical Oncologist, Chief, Genitourinary
Oncology Service; D. Wayne Calloway Chair in Urologic
Oncology, Memorial Sloan Kettering, NY, USA
“CTC Molecular Characterization Predicts Response to
Taxane chemotherapy in Prostate Cancer: from
mechanism to clinical application”
Evi Giannakakou, Ph.D. Professor of Pharmacology in
Medicine, Director of Laboratory Research, Division of
Hematology and Medical Oncology, Weill Cornell
Medicine, NY, USA
10:30 – 11:00
Networking Coffee Break in the Exhibition Hall
11:00 – 11:30
PL3-5
11:30 – 12:00
PL3-6
12:00 – 12:30
PL3-7
“Analyses of circulating tumor DNA for monitoring
tumor genome evolution”
Michael Speicher, MD, Professor and Chairman of the
Institute of Human Genetics, Medical University of Graz,
Austria
“CTCs and ctDNA monitoring melanoma patients in
early stage and advance stages during treatment.”
Dave Hoon, Ph.D, Director, Department of Molecular
Oncology, John Wayne cancer Institute, Santa Monica, CA,
USA.
“The diversity of CTCs and DTCs in ovarian cancerwhat is the role of the tumor microenvironment?”
Sabine Kasimir-Bauer, PhD, Professor, Head of Laboratory,
Dep. of Gynecology and Obstetrics, University Hospital of
Essen, Germany
12:30 – 14:00
Lunch Break
3
14:00 – 15:30
ORAL PRESENTATIONS Session 1
15:30 – 16:30
POSTER SESSION 2
Networking coffee break in the Exhibition Hall
16:30 – 18:00
Drug Development Forum : “Applications of liquid biopsy in clinical drug
development”
(CTC Companies Sponsored Oral Presentations)
(n=3 Speakers, 30 min each)
16:30 – 17:00
17:00 – 17:30
17:30 – 18:00
19.00 pm – 10.00 pm Faculty Dinner
4
DAY 3: Friday, October 6
Time
Session/Title
Confirmed Speaker
Friday, October 6
8:30 – 12:00
Plenary Lecture Session 4:
Recent advances on the Isolation, Enumeration and Molecular characterization of
CTCs
8:30 – 9:00
“Recent advances in the isolation and Molecular
PL4-1
characterization of Circulating Tumor Cells”
Leon Terstappen, Professor, Faculty of Science and
Technology, MIRA Research Institute, Department of
Medical Cell BioPhysics, University of Twente, Enschede,
the Netherlands
9:00 – 9:30
“Propagation and Reliable Expansion of CTC: New
PL4-2
Promise and Technologies”
Richard J. Cote, Professor and Joseph R. Coulter Jr. Chair,
Department of Pathology & Laboratory Medicine
Director, Dr. John T. Macdonald Foundation Biomedical
Nanotechnology Institute, University of Miami Miller
School of Medicine
9:30 – 10:00
“In vitro expansion of colon Circulating Tumor Cells:
PL4-3
Molecular portrait of metastasis-competetent CTCs”
Catherine Alix-Panabières, Laboratoire Cellules
Circulantes Rares Humaines - LCCRH , Institut de
Recherche en Biothérapie - IRB , Hôpital Saint-Eloi CHRU Montpellier, France
10:00 – 10:30
10:30 – 11:00
PL4-4
11:00 – 11:30
PL4-5
11:30 – 12:00
PL4-6
12:00 – 13:00
13:00 – 14:30
14:30 – 16:00
Networking Coffee Break in the Exhibition Hall
“Models for Studying CTCs and Metastatic Biology”
Stefanie S. Jeffrey, MD, John and Marva Warnock
Professor, Department of Surgery, Chief of Surgical
Oncology Research, Stanford University, School of
Medicine, Stanford, USA
“The Blood Profiling Atlas in Cancer: tracing the
temporal evolution in cancer”
Peter Kuhn, Professor, USC Dornsife, Los Angeles, CA ,
USA
“Development and clinical evaluation of multiplex
molecular assays for CTC molecular characterization”
Evi Lianidou, Professor, ACTC lab, Dept of Chemistry,
University of Athens, Greece.
Lunch Break - Exhibition visit
ORAL PRESENTATIONS Session 3
POSTER SESSION 3: New technologies for CTC
5
Isolation, Enumeration and Molecular characterization
And
networking coffee break in the Exhibition Hall
16:00 – 17:30
Technology Forum : “State of the art technological platforms for liquid biopsy
analysis”
(CTC Companies Sponsored Oral Presentations)
(n=3 Speakers, 30 min each)
16:00 – 16:30
16:30 – 17:00
17:00 – 17:30
20.00 Gala dinner party
6
DAY 4: Saturday, October 7
Time
9.00 – 9.30
PL5-1
9:30 – 10:00
PL5-2
10:00 – 10:30
PL5-3
10:30 – 11:00
Session/Title
Confirmed Speaker
9:00 – 10:30
Plenary Lecture Session 5:
Circulating tumor DNA in clinical practice
“Genome-wide approaches for analyzing plasma DNA for
cancer detection”
Dennis Lo, Professor, Li Ka Shing Institute of Health
Sciences, The Chinese University of Hong Kong, Shatin,
New Territories, Hong Kong SAR, China
“Novel clinical applications of cancer genetics for therapy
and diagnosis”
Luis Diaz, Associate Professor of Oncology, Johns Hopkins
University School of Medicine, USA
“Liquid biopsies and cancer evolution”
Alberto Bardelli, PhD, Institute for Cancer Research and
Treatment, Department of Oncology, University of Torino,
Candiolo, Italy
Networking Coffee Break in the Exhibition Hall
11:00 – 13:00
Plenary Lecture Session 6:
Future challenges in Liquid Biopsies
11:00 – 11:30
PL6-1
11:30 – 12:00
PL6-2
12:00 – 12:30
PL6-3
12:30 – 13:00
PL6-4
“About Chomsky, Motifs and Patterns in circulation noncodingRNAs”
George Calin,, MD, PhD, Professor, Department of
Experimental Therapeutics, Division of Cancer Medicine,
The University of Texas MD Anderson Cancer Center,
Houston, TX, USA
"Strategies to Exploit the Biology of Exosomes for
Diagnosis and Treatment of Cancer"
Raghu Kalluri, MD, PhD, Department of Cancer Biology,
Metastasis Research Center, University of Texas MD
Anderson Cancer Center, Houston, TX, USA
“Novel approaches in identifying and sequencing traces of
tumor and tissue-specific nucleic acids in liquid biopsies”
Mike Makrigiorgos, PhD, Professor and Director, Medical
Physics and Biophysics, Dana-Farber Cancer Institute and
Harvard Medical School, Boston, USA
“Liquid Biopsy: How close are we now to routine clinical
practice??”
Maurizio Ferrari, MD, President of the International
Federation of Clinical Chemistry (IFCC), Professor of
Clinical Pathology University Vita-Salute San Raffaele
Director of Clinical Molecular Biology and Cytogenetics
Laboratory, Head of Unit Genomics for Diagnosis of Human
Pathologies, IRCCS San Raffaele - Milan (Italy)
7
13:00 – 14:00
Lunch
14:00 – 15:00
Shaping the future in Liquid Biopsies:
Presentations of Liquid Biopsy Consortia in Europe and US
14:00 – 14:30
14:30 – 15:00
15:00 – 15:30
Europe: “The Cancer – ID project: Cancer treatment
and monitoring through identification of circulating
tumour cells and tumour related nucleic acids in blood”
Thomas Schlange, PhD, Senior Biomarker Scientist,
Global Biomarker Research, Bayer Pharma
USA: "Blood Profiling Atlas in Cancer (Blood PAC):
Catalyzing Collaboration to Advance Cancer Care"
Dr. Lauren Leiman, Senior Director, External Partnerships
at White House Cancer Moonshot Task Force, USA
USA: title to be announced
Jerry S.H. Lee, PhD, Deputy Director, Center for Strategic
Scientific Initiatives (CSSI), Office of the Director, National
Cancer Institute, NIH, USA
15:30 – 16:30
Presentation of travel awards
Presentation of best poster presentation awards
Closing Remarks
Evi Lianidou, Klaus Pantel
8
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