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Brianna Loeck HIV-Human Immunodeficiency Virus AIDS-Acquired Immune Deficiency Syndrome ______________________________________________ Scientists identified a type of chimpanzee in West Africa as the source of HIV infection in humans They believe the chimpanzee version (Simian Immunodeficiency Virus or SIV) was most likely transmitted by humans hunting these chimpanzees for meat and had come in contact with their infected blood (CDC, 2011) Over decades, the virus slowly spread across Africa and later into other parts of the world Currently, 33.4 million people globally, are living with HIV/AIDS and more than 25 million people worldwide have died of AIDS since the first case reported in1981 (AIDS.gov, 2012) About 97% of people living with HIV are low and middle-income countries such as sub-Saharan Africa (AIDS.gov, 2012) At the end of 2009, an estimated 1,148,200 people aged 13 and older were living with HIV in the United States (CDC, 2012) Gay and bisexual men (2% of the population) remain the population most heavily affected by HIV in the United States (accounted for more than 50% of HIV infections) (CDC, 2012) African Americans (14% population, 44% HIV infections) and Hispanics/Latinos (16% population, 20% of HIV infections) are the racial/ethnic groups most affected by HIV (CDC, 2012) Unprotected sex with an infected person Having multiple sex partners or the presence of other sexual transmitted diseases (STDs) Using unsterile needles or syringes for drug use Being born by an infected mother which can be passed through child birth or breast-feeding ________________________________________________ A few low risk ways for HIV to be contracted but are not common are: receiving blood transfusions, open-mouth kissing, contact of broken skin or wounds, and/or being bitten by an infected person HIV is not transmitted in the following ways: air or water, insect bites, saliva, tears or sweat, casual contact and closed mouth kissing Most common, high-risk way to contract HIV HIV is detected through a person’s semen, blood and vaginal fluids, therefore by engaging in unprotected sex with an infected person puts one at high risk of contracting it also (NIAID, 2009) One simply cannot tell by looking at someone if they have HIV, so that is why it’s extremely important to take precautions to protect yourself Unfortunately many people do not believe it is necessary to be tested if they show no signs or symptoms The NIAID strongly recommends getting tested regularly, practicing abstinence, remaining faithful to your partner, proper use of condoms, and not sharing needles Currently research is being done on more ways to help stop the transmission of HIV to others that are not infected such as antivirals, topical creams and vaccines (NIAID, 2009) The second most common risk of HIV infection The most common illegal drugs that are injected are cocaine, heroin, and methamphetamine Why? Because it gives them satisfaction, creates alertness, increased in sensitivity, and to be able to relax (AVERT, 2011) There are other ways of consuming drugs however people like to inject them because it’s more likely to cost-efficient and a rapidly acting method (AVERT, 2011) According to AVERT (2011), “stigma and discrimination against drug users need to be tackled so they can access treatment and reduce the risk of being exposed to HIV” When children are born with HIV and the mother’s did not use treatment, their life expectancy is usually a couple of years due to the rapidness of the virus spreading (UNICEF, 2011) “Expanding HIV testing and counseling among pregnant women is critical for identifying those in need of follow-up care and increasing coverage of subsequent interventions to reduce the risk of mother-to-child transmission of HIV,” states UNICEF (2011) According to UNICEF (2011), the goal of the Global Plan for children is to eliminate new HIV infections by the year of 2015 and keeping their mothers alive Throughout the years, CDC has a Division of HIV/AIDS Prevention (DHAP) that “has developed a comprehensive program of HIV surveillance to collect, analyze, and disseminate data of HIV infection and AIDS” (CDC, 2012) 2 MAIN WAYS DATA IS COLLECTED Passive reporting is defined as, “combinations of health practitioners, hospitals, clinics and laboratories report cases of HIV/AIDS to state and local health department” (CDC, 2012) Active reporting is defined as “state and local health department surveillance personnel collect information by contacting health care practitioners and reviewing medical records in hospitals and clinks” (CDC, 2002) Demographic characteristics such as: gender race age locality mode of exposure of HIV opportunists illnesses and virologic and immunologic status supplemental information such as prescription of antiviral’s and other therapies use of medical and substance abuse treatment services and health insurance coverage monitor the incidence and prevalence of HIV and AIDS monitor HIV-related morbidity and mortality in the population estimate incidence of HIV infection identify changes in trends of HIV transmission and identify populations at risk target prevention interventions and evaluate their effectiveness allocate funds for social and health services to facilitate access to health, social and prevention services, including medical treatment (CDC, 2002). Biological factors associated with HIV transmission are numerous and complicated A type of biological characteristic would be the type of bodily fluid one comes in contact with: “Characteristics on which a determination of the probability of sexual transmission depends include the concentration of HIV in the fluid, the integrity or relative vulnerability of involved mucous membranes (such as those inside the anus, vagina, or mouth), the duration of exposure, and the strain of virus transmitted” Remedy Health Media (1998) Another biological characteristic would be the route of transmission, “HIV-infected bodily fluids can be swallowed, accepted into the vagina or rectum, or injected directly into the bloodstream” (Remedy Health Media, 1998) Epidemiologists have studied and researched the risk level of becoming infected with HIV based off of both biological characteristics recently mentioned Ex.) hugging or shaking hands with someone whom is infected is not associated with any risk of contracting HIV However, sharing needles with someone who has HIV is very high risk because of the transmissions of bodily fluids being exposed (Remedy Health Media, 1998) Other risks are sexual contact, but depending on what type of contact is done it each has its own risk levels Example of low risk transmission is oral sex, followed by vaginal intercourse being higher of a risk, then anal sex being the highest risk of all due to semen coming in contact with abrasions in the anal wall HIV is known to be a spherical shape made up of two main parts: the envelope and the core. The envelope or membrane, is the outer coat of the virus that is “composed of two layers of fatty molecules called lipids, taken from the membrane of a human cell when a newly formed virus particle buds from the cell” (NIAID, 2012). Throughout the envelope are proteins from the host cell as well as an average of 72 copies of complex HIV protein known as Env Within the Env is a particle called the ‘virion” which spike through the surface of the virus “Env consists of a cap made of three molecules called glycoprotein 120 (gp120), and a stem consisting of three molecules called gyclcoprotein 41 (gp41) that anchor the structure in the viral envelope” (NIAID, 2012) Within the viral envelope there is a bullet-shaped core known as the capsid, which is made up by the protein p24 Inside the core are three enzymes required for HIV replication called reverse transcriptase, integrase and protease (Avert 2011) Also within the capsid are two strands of RNA HIV has several genes, which “produce proteins that control the ability of HIV to infect a cell, produce new copies of the virus, or cause disease” (NIAID, 2012) RNA has a very similar structure to DNA. However, small differences between the two molecules mean that HIV's replication process is a bit more complicated than that of most other viruses (Avert, 2011) HIV treats genes in the same way as human genes, which is why HIV replicates itself and can result into AIDS if not treated at the beginning stage of infection That is why there are antiviral medication to be taken to help slow down the replication of HIV to prevent it from causing AIDS According to Schneider (2011) Humans are social creatures, and their behavior is strongly affected by their social environment There are quite a few of behavioral factors that play into HIV/AIDS, one being the lack of knowledge about HIV/AIDS AMFAR (2010) states, “American youth today are growing up at a time when AIDS is considered to be a treatable disease and complacency is widespread, young people may be more likely to have misconceptions about HIV/AIDS, including modes of transmission and preventive measures” Since antiviral’s became available to those who are infected with HIV research has shown that the youth is at greater risk of engaging in risky sexual activity There is also evidence that proves since HAART (highly active antiretroviral therapy) became available, the prevalence of unprotected sex has increased in the general population (AMFAR, 2012) Another behavioral factor is substance use When people are experimenting with alcohol and drugs, there is an increased risk of risky behavior AMFAR (2012) states, “Substance abuse may lead to inconsistent condom use and selection of high-risk sexual partners by both young men and women” The use of ecstasy, methamphetamine and amyl nitrites and other illegal drugs have been linked with unprotected sexual activity, particularly among young MSM (males that have sex with males) (AMFAR, 2012) Along with these behaviors associated with HIV/AIDS are mental health issues, socials norms and sexual networks, homophobia, stigma and discrimination, and relationship dynamics, sexual coercion, and sexual abuse A behavioral factor is sexual behavior Engaging in risky sexual activities is the primary mode of HIV transmission According to a CDC survey in 2009, 46% of all high schools students have engaged in sexual intercourse and 34% of them did not use a condom the last time they had sex African Americans were at 65.2%, Hispanics at 49.1%, and Caucasians at 42% (AMFAR, 2012) Educational interventions were then targeted to the youth who were not sexually active yet to highlight the importance of providing sexual health and risk reduction information (AMFAR, 2012) Depending upon the country, subpopulations and communities are at higher behavior risk due to several reasons such as occupation, migration status, sexual orientation, geographic location, education and income (UNAIDS, 1998) AIDS disproportionately affects different parts of the country due to higher populations, such as Miami and Jacksonville FL, Baton Rouge, LA, New York City, NY, and Washington DC (CDC, 2012) Stigma and discrimination still continue to be a serious issue in today’s society despite our knowledge and/or little knowledge about this disease People have created a social stigma against people whom are HIV positive and continue to discriminate towards them based on their status 1. 2. 3. 4. 5. The transtheoretical model applies to HIV/AIDS based on an individual participating in unhealthy behaviors such as unprotected intercourse with multiple people or sharing needles with other drug users. The individual has no desire to change their unhealthy habits, such as continue to use infected needles and engaged in sexual risky behaviors They increase their awareness and learn the difficulties of those changes, yet are not ready to make those changes The person chooses to try to change their unhealthy behavior by reaching out and reading more information and risks involved Taking action; such as using clean sterile needs instead of used ones and by using condoms during sexual activity Continue to practice safe and healthy behaviors such as always using a condom during sexual activity and to hopefully stop utilizing drugs completely “More awareness is needed so that no one with HIV/AIDS is stigmatized or discriminated against” - President Obama (2011) _______________________________________________________________________________________________________________ President Obama created the National HIV/AIDS Strategy in 2010, to address the stigma and discrimination of people who are positive with this virus Obama states, “The United States will become a place where new HIV infections are rare and when they do occur, every person regardless of age, gender, race/ethnicity, sexual orientation, gender identity or socio-economic circumstance, will have unfettered access to high quality, life-extending care, free from stigma and discrimination” (White House, 2012) The Strategy included three primary goals: reducing the number of people who become infected with HIV, increasing access to care and improving health outcomes for people living with HIV, and reducing HIV-related disparities (Healthy People, 2012) 1. 2. 3. 4. The Strategy also has four major steps needing to reduce the stigma and discrimination of people living with HIV/AIDS. First is to engage communities to support people with HIV/AIDS such as faith communities, businesses, schools & community-based organizations Promote public leadership of people living with HIV such as governments, HIV services organizations, and other institutions Promote public health approaches to HIV prevention and care, for example, state legislatures should consider reviewing HIV-specific criminal statutes to ensure that they are consistent with current knowledge of HIV transmission Strengthen enforcement of civil rights laws by having The Department of Justice and Federal agencies enhance cooperation to facilitate enforcement of Federal antidiscrimination laws (White House, 2012) Obama’s Strategy for HIV/AIDS is a great example of the Ecological Model. The Ecological Model consists of “five levels of influence that determine healthrelated behaviors; each level is a potential target for health promotion intervention” (Schneider, 2011) _____________________________________________________________________ Intrapersonal-one will learn about education, knowledge, and their beliefs about HIV/AIDS and carry that will them throughout life. Interpersonal-one will learn behaviors from family, friends or co-workers, whether it be positive or negative. For example, a teen engaging in risky sexual behaviors which can stem off of peer pressure or other risky behaviors such as drug and alcohol use. One then makes their own discussions not necessarily thinking about the consequences. Institutional-which falls under schools and work places. Relating to Obama’s HIV/AIDS Strategy, this would be the step of engaging communities to support people with HIV/AIDS Community-which can be a huge influence on behavior. Organizations can join together in helping promote and support HIV individuals. The more organizations and businesses involved help promote more awareness Public policy-which is developing and enforcing state and local policies that can increase health behaviors. Obama’s public policy for his program is to “strengthen enforcement of civil rights laws by having The Department of Justice and Federal agencies enhance cooperation to facilitate enforcement of Federal anti-discrimination laws” (White House, 2012) Obama also created the Emergency Plan for AIDS Relief (PEPFAR) which was designed to help save people’s lives suffering from HIV/AIDS Some of PEPFAR’s goals: transition from an emergency response to promotion of sustainable country programs strengthen partner government capacity expand prevention, care, and treatment integrate and coordinate programs to maximize impact on health systems invest innovation and operations research to evaluate impact improve service delivery and maximize outcomes (State Department Office, 2011) HIV is a preventable disease One must be knowledgeable about this particularly disease along with the risk factors and prevention It is extremely important to regularly get tests for HIV/STD’s to prevent transmission to others Local health departments and clinics offer information and HIV/STD testing's for anyone As the number of HIV infections grow, it is important to increase prevention, interventions and programs so people are aware We, as a nation, can only hope that soon there will be a vaccine or cure created to end this pandemic AIDS.gov. (2012, July 6). U.S Statistics. Retrieved from http://aids.gov/hiv-aids-basics/hiv-aids-101/statistics/ AMFAR. (2010, September). Youth and HIV/AIDS in the U.S: Challenges and Opportunities for Prevention. Retrieved from http://www.amfar.org/uploadedFiles/In_the_Community/Publications/Youth.pdf?n=5282 AVERT. (2011). Injecting Drugs, Drug Users, HIV & AIDS. Retrieved from http://www.avert.org/injecting.htm AVERT. (2011). The Structure of HIV. Retrieved from http://www.avert.org/hiv-virus.htm Center for Disease Control and Prevention. (2012, April 11). Basic Information about HIV and AIDS. Retrieved from http://www.cdc.gov/hiv/topics/basic/ Center of Disease Control and Prevention. (2012, September 24). Surveillance Systems Supported by the Division of HIV/AIDS Prevention. Retrieved from http://www.cdc.gov/hiv/topics/surveillance/resources/factsheets/surveillance.htm Center of Disease Control and Prevention. (2002, March 1). HIV/AIDS Surveillance Methods. Retrieved from http://www.cdc.gov/hiv/topics/surveillance/resources/slides/methods/index.htm Healthy People. (2012, September 6) HIV. Retrieved from http://www.healthypeople.gov/2020/topicsobjectives2020/overview.aspx?topicid=22 National Institute of Allergy and Infectious Diseases. (2009, March 25). HIV/AIDS. Retrieved from http://www.niaid.nih.gov/topics/HIVAIDS/Understanding/Pages/riskFactors.aspx National Institute of Allergy and Infectious Disease. (2012, April 3). HIV/AIDS. Retrieved from http://www.niaid.nih.gov/topics/hivaids/understanding/biology/Pages/structure.aspx Remedy Health Media. (1998). The Complete HIV/AIDS Resource. Retrieved from http://www.thebody.com/content/art14042.html Schneider, M. J. (2011). Introduction to public health (3rd Ed) Mississauga, Ontario: Jones and Bartlett Publishers Canada State Department Office of the U.S. (2011, January 7). About PEPFAR. Retrieved from http://www.pepfar.gov/about/index.htm The White House: Office of the Press Secretary. (2012, July 21). HIV/AIDS-Related Stigma and Discrimination. Retrieved from http://www.whitehouse.gov/the-press-office/2012/07/21/fact-sheet-hivaids-related-stigma-and-discrimination UNAIDS. (1998, May). Meeting the Behavioral Data Collection Needs of National HIV/AIDS and STD Programs. Retrieved from http://www.unaids.org/en/media/unaids/contentassets/dataimport/publications/irc-pub03/meetingbehavdata_en.pdf UNICEF. (2012, September). Monitoring the Situation of Women and Children. Retrieved from http://www.childinfo.org/hiv_aids_mother_to_child.html United Nations. (1998, November 10). The Demographic Impact of HIV/AIDS. Retrieved from http://www.un.org/esa/population/pubsarchive/hivmtg/aidsrep.pdf World Health Organization. (2012, July). HIV/AIDS. Retrieved from http://www.who.int/mediacentre/factsheets/fs360/en/index.html