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FIRST JOINT MEETING OF THE EUROPEAN FEDERATION OF AUTONOMIC SOCIETIES & AMERICAN AUTONOMIC SOCIETY Academic Medical Center Amsterdam, the Netherlands October 20-23, 2004 Preliminary Program WEDNESDAY, OCTOBER 20, 2004 7:30-8:30 8:30-17:00 REGISTRATION PRECOURSE - HIGHS AND LOWS OF BLOOD PRESSURE. UPDATE ON RAPID CHANGES IN BLOOD PRESSURE Sponsored by an unrestricted educational grant from Finapres Medical Systems INTRODUCTION 8:30-8:35 Introduction W Wieling Amsterdam, the Netherlands DEVICES AND SOFTWARE 8:35-9:10 Non-invasive beat-to-beat blood pressure monitoring G Parati Milan, Italy 9:10-9:45 Cardiac output JJ van Lieshout Amsterdam, the Netherlands 9:45-10:20 Syncope and the heart B Levine Dallas, TX, USA 10:20-10:35 The mercurial nature of blood pressure: highs and lows in a changing climate W Wieling Amsterdam, the Netherlands 10:35-11:00 COFFEE BREAK PAROXYSMALS OF LOW BLOOD PRESSURE 11:00-11:35 Unconscious confusion: defining syncope and related concepts JG van Dijk Leiden, the Netherlands 11:35-12:10 Syncope: from phenomenology to physiology R Freeman Boston, MA, USA 12:10-12:45 Syncope 2004: what works, what doesn't R Sheldon Calgary, Canada 12:45-14:00 LUNCH & POSTER SESSION 1 -214:00-14:35 14:35-15:10 15:10-15:45 15:45-16:15 16:15-17:00 18:00-19:00 The circadian rhythm of blood pressure, pathophysiology and clinical relevance G van Montfrans Amsterdam, the Netherlands Denervation of baro- and chemoreceptors JM Karemaker Amsterdam, the Netherlands Pheochromocytoma JWM Lenders Nijmegen, the Netherlands TEA BREAK The future of integrated physiology in an age of molecular biology M Joyner Rochester, MN, USA RECEPTION - CITY HALL THURSDAY, OCTOBER 21, 2004 8:30-9:15 PLENARY LECTURE White adipose tissue: getting nervous E Fliers Amsterdam, the Netherlands EXERCISE AND INTEGRATIVE AUTONOMIC PHYSIOLOGY CHAIRS: MARK CHAPLEAU & BENJAMIN LEVINE Sponsored by an unrestricted educational grant from Eli Lilly 9:15-9:30 Preserved contribution of nitric oxide to baseline vascular tone in deconditioned human skeletal muscle M Bleeker, M Kooijman, G Rongen, M Hopman, P Smits Nijmegen, the Netherlands 9:30-9:45 Impact of simulated microgravity and caloric restriction on norepinephrine transporter function and adrenoreceptor sensitivity M Boschmann, F Adams, K Schaller, J Tank, S Klaus, F Luft, J Jordan Berlin, Germany 9:45-10:00 10:00-10:15 10:15-10:30 TRAVEL FELLOWSHIP AWARDEE (SPONSORED BY FINAPRES MEDICAL SYSTEMS) Mechanism for increasing cardiac output during dynamic exercise with variable heart rate LWJ Bogert, A Erol-Yilmaz, R Tukkie, AA Wilde, W Wieling, JJ van Lieshout Amsterdam, the Netherlands Effects of midodrine on exercise-induced hypotension and blood pressure recovery in autonomic failure W Schrage, J Eisenach , F Dinenno, S Roberts, C Johnson, P Sandroni, P Low, M Joyner Rochester, MN, USA Contribution of the sympathetic nervous system to vascular resistance during head-up tilt M Kooijman, GA Rongen, P Smits, MTE Hopman Nijmegen, the Netherlands -310:30-10:45 Coffee Break HYPERTENSION AND OTHER CARDIOVASCULAR DISEASES/EXPERIMENTAL MODELS CHAIRS: JACQUES LENDERS & RONALD SCHONDORF Sponsored by an unrestricted educational grant from AstraZeneca 10:45-11:00 Impaired cerebral autoregulation in patients with malignant hypertension RV Immink, BJH Van den Born, GA Van Montfrans, JM Karemaker, RP Koopmans, JJ Van Lieshout Amsterdam, the Netherlands 11:00-11:15 TRAVEL FELLOWSHIP AWARDEE (SPONSORED BY FINAPRES MEDICAL SYSTEMS) Metabolic and cardiovascular impact of the autonomic nervous system in obesity C Shibao, A Gamboa, A Diedrich, AC Ertl, KY Chen, G Farley, S Paranjape, M Boschmann, J Jordan, I Biaggioni Nashville, TN, USA 11:15-11:30 Early cardiac autonomic impairment in Parkinson’s disease F Perego, F Barbic, M Gianni, S Biagiotti, M Borella, G Cantoni, A Malliani, R Furlan Milan, Italy 11:30-11:45 Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model CJ Charles, DL Jardine, MG Nicholls Christchurch, New Zealand 11:45-12:00 NET knockout mice exhibit bradycardia and reduced blood pressure in response to fear NR Keller, M Appalsamy, A Diedrich, D Robertson Nashville, TN, USA 12:00-14:00 LUNCH & POSTER SESSION 2 FRIDAY, OCTOBER 22, 2004 8:30-9:15 PLENARY LECTURE Reflexes from the heart and lungs R Hainsworth Leeds, United Kingdom ORTHOSTATIC INTOLERANCE & ORTHOSTATIC HYPOTENSION CHAIRS: MICHAEL JOYNER & CARLOS MORILLO Sponsored by an unrestricted educational grant from CN Systems 9:15-9:30 The relation of postural vasovagal syncope to splanchnic hypervolemia in adolescents J Stewart Valhalla, NY, USA 9:30-9:45 Neurocirculatory abnormalities in chronic orthostatic intolerance DS Goldstein, B Eldadah, C Holmes, S Pechnik, J Moak, Y Sharabi Bethesda, MD, USA 9:45-10:00 Human cerebral venous outflow pathway depends on posture and central venous pressure J Gisolf, JJ van Lieshout, K van Heusden, F Pott, WJ Stok, JM Karemaker Amsterdam, the Netherlands -410:00-10:15 Autoregulation of cerebral blood flow in orthostatic hypotension W Singer, SM Hines, IR Zimmerman, PA Low Rochester, MN, USA 10:15-10:30 The heightened blood pressure response to nitric oxide synthase inhibition in persons with tetraplegia is independent of sympathetic stimulation J Wecht, J Weir, AM Krothe, A Spungen, W Bauman Bronx, NY, USA 10:30-10:45 COFFEE BREAK PHARMACOLOGY AND TREATMENT CHAIRS: PIETRO CORTELLI & ITALO BIAGGIONI Sponsored by an unrestricted educational grant from GlaxoSmithKline 10:45-11:00 TRAVEL FELLOWSHIP AWARDEE (SPONSORED BY THE AMERICAN AUTONOMIC SOCIETY) Effects of tyramine on tissue perfusion and metabolism in subcutaneous adipose tissue F Adams, M Boschmann, B Brauer, FC Luft, S Klaus, J Jordan Berlin, Germany 11:00-11:15 Clonidine, a potential treatment for supine hypertension and pressure natriuresis in autonomic failure patients C Shibao, R Abraham, SR Raj, B Black, D Robertson, TL Davis, I Biaggioni Nashville, TN, USA 11:15-11:30 Octreotide and midodrine act synergistically in patients with POTS RD Hoeldtke, KD Bryner, M Hoeldtke, G Hobbs Morgantown, WV, USA 11:30-11:45 Acetylcholinesterase inhibition decreases orthostatic tachycardia in the postural tachycardia syndrome S Raj, B Black, I Biaggioni, P Harris, D Robertson Nashville, TN, USA 11:45-12:00 Effects of legcrossing and skeletal muscle tensing in patients with vasovagal syncope N van Dijk, IJ de Bruin, J Gisolf, HAR de Bruin-Bon, M Linzer, JJ van Lieshout, W Wieling Amsterdam, the Netherlands 12:00-14:00 LUNCH & POSTER SESSION 3 14:00-14:45 SIR ROGER BANNISTER LECTURE The challenge of mapping central autonomic centers and pathways in humans C Mathias London, United Kingdom PERIPHERAL AND CENTRAL AUTONOMIC DISORDERS CHAIRS: JENS JORDAN & JANICE GILDEN 14:45-15:00 Autonomic symptoms and diabetic neuropathy: a population-based study P Low, L Benrud-Larson, D Sletten, T Opfer-Gehrking, S Weigand, P O'Brien, G Suarez, P Dyck Rochester, MN, USA -515:00-15:15 15:15-15:30 15:30-15:45 15:45-16:00 16:00-17:00 16:00-16:45 16:45-17:00 17:00-17:15 17:15-18:30 18:30-19:30 19:30 Comparison of stimulated skin wrinkling with sympathetic skin reflex, intraepithelial nerve fiber density and nerve conduction E Wilder-Smith, A Chow Singapore Increased endothelial nitric oxide function in autonomic failure A Gamboa, C Shibao, A Diedrich, B Black, G Farley, S Raj, D Robertson, I Biaggioni Nashville, TN, USA SDS/MSA RESEARCH AWARDEE Differentiating between primary dysautonomias - multiple system atrophy, pure autonomic failure and Parkinson’s disease: a pathophysiology-based approach Y Sharabi, B Eldadah, S Pechnik, C Holmes, D Goldstein Tel Hashomer, Israel TEA BREAK DAVID H. P. STREETEN SESSION STREETEN LECTURE My journey with the autonomic nervous system P Low Rochester, MN, USA STREETEN TRAVEL FELLOWSHIP AWARDEE (SPONSORED BY THE AMERICAN AUTONOMIC SOCIETY) Baroreflex regulation of muscle sympathetic nerve activity does not reset during chronic antihypertensive therapy: A potential mechanism for treatment failure? Q Fu, R Zhang, E Maritini, S Witkowski, A Prasad, K Okazaki, A Arbab-Zadeh, B Levine Dallas, TX, USA AWARDS SESSION TRAVEL TIME CANAL BOAT TOUR PRESIDENTIAL DINNER - THE GRAND SATURDAY, OCTOBER 23, 2004 8:00-9:30 BREAKFAST & POSTER SESSION 4 Sponsored by an unrestricted educational grant from Vitatron BAROREFLEX CHAIRS: ROGER HAINSWORTH & DAVID GOLDSTEIN 9:30-9:45 Cardiac vagal motoneurons: effect of clonidine on pressure-activity relationship A Cividjian, N Rentero, L Quintin Lyon-Villeurbanne, France 9:45-10:00 Hydrogen peroxide/hydroxyl radical generated during action potential firing inhibits membrane excitability of baroreceptor and vagal afferent neurons V Snitsarev, O Yermolaieva, C Whiteis, F Abboud, M Chapleau Iowa City, IA, USA -610:00-10:15 10:15-10:30 10:30-10:45 10:45-11:15 11:15-11:30 11:30-11:45 11:45-12:00 12:00-12:15 12:15-13:00 Influences of central venous pressure and plasma osmolality on control of sympathetic activity in humans N Charkoudian, DE Wick, SK Roberts, JH Eisenach, MJ Joyner Rochester, MN, USA Preserved baroreflex buffering of blood pressure but not of heart rate in elderly humans S Volianitis, CC Yoshiga, T Vogelsang, NH Secher Copenhagen, Denmark COFFEE BREAK AAS BUSINESS MEETING Medullary pathology in patients with carotid sinus syndrome V Miller, RA Kenny Newcastle upon Tyne, United Kingdom Baroreflex failure as a late sequela of neck irradiation Y Sharabi, R Dendi, C Holmes, D Goldstein Tel Hashomer, Israel Increased latency in the baroreflex-mediated vascular resistance response in subjects with poor tolerance to orthostatic stress G Gulli, V Cooper, V Claydon, R Hainsworth Leeds, United Kingdom Extreme challenges on autonomic cardiovascular control during gravity transitions B Verheyden, F Beckers, A Aubert Leuven, Belgium PLENARY LECTURE Molecular mechanisms of sensory transduction in health and disease FM Abboud Iowa City, IA, USA WEDNESDAY, OCTOBER 20, 2004 12:45-14:00 POSTER SESSION 1 CHAIRS: WOUTER WIELING & JULIAN STEWART HYPERTENSION AND OTHER CARDIOVASCULAR DISORDERS Poster #1 Should nocturnal systolic blood pressure be treated in patients with ORAL neurogenic orthostatic hypotension? A prospective survival study A Pathak, B Bourdet, JL Montastruc, J Amar, JM Senard Toulouse, France Poster #2 Orthostatic low blood pressure in treated chronic heart failure patients ORAL LWJ Bogert, JAP van der Sloot, GA van Montfrans, JJ van Lieshout Amsterdam, the Netherlands Poster #3 Stroke in autonomic failure ORAL WP Cheshire, JF Meschia, P Sandroni, EE Benarroch, PA Low Jacksonville, FL, USA Poster #4 Increased sympathetic tone and work stress in Finnish media workers H Lindholm, J Ahlberg, M Partinen, A Savolainen Helsinki, Finland -7Poster #5 ORAL Is central serotoninergic response to orthostatic stress chronically impaired in patients with neurocardiogenic syncope? JC Guzman, RG Garcia, P Lopez-Jaramillo, R Dillenburg, M Kamath, SJ Connolly, CA Morillo Hamilton, Canada Poster #6 Cardiodynamic characterization during head up tilt test in patients with neurocardiogenic syncope JC Guzman, R Dillenburg, M Kamath, SJ Connolly, CA Morillo Hamilton, Canada SYNCOPE/ORTHOSTATIC INTOLERANCE Poster #7 Cerebrovascular reactivity to hypocapnia and its relationship with ORAL orthostatic tolerance L Norcliffe, R Hainsworth Leeds, United Kingdom Poster #8 POTS and long QT: just a coincidence? S Garcês, F Araújo, F Rego, J Ducla-Soares Lisboa, Portugal Poster #9 Psychiatric profile and attention deficits in the postural tachycardia syndrome V Raj, K Haman, S Raj, R Blakely, D Robertson, R Shelton Nashville, TN, USA Poster #10 Do we need a reflex tachycardia to stand-up? JO Fortrat, C Lemarié, E Bellard, J Victor Angers, France Poster #11 Autonomic cardiovascular responses to head up tilt (HUT) and the effects of ORAL tilt training in syncope patients B Verheyden, F Beckers, T Reybrouck, H Ector, A Aubert Leuven, Belgium Poster #12 The tilt table test protocol: how it can be improved? L Medina, A Marmol, S Ossaba, M Duque, W Uribe, M Olaya, J Marin, Y Torres, J Velasquez Medellín, Colombia Poster #13 Fatigue: A clue symptom in chronic orthostatic disorder. How can it be explained? L Medina, M Olaya, F Restrepo, M Duque, W Uribe, L Mesa, J Marin, J Velasquez, Y Torres Medellín, Colombia Poster #14 Variability and coherence of RR-intervals and systolic blood pressure during ORAL head-up tilt in normal individuals AB Pedersen, J Mehlsen Frederiksberg, Denmark Poster #15 Experimental induction of panic symptoms in patients with orthostatic intolerance and orthostatic tachycardia R Khurana Baltimore, MD, USA -8Poster #16 Does heart rate and blood pressure variability differ between normal individuals and patients with cardioinhibitory or vasodepressor response to head-up tilt? J Mehlsen, AB Pedersen Frederiksberg, Denmark Poster #17 Physical counter maneuvers are effective in diminishing initial orthostatic ORAL hypotension CTP Krediet, W Wieling Amsterdam, the Netherlands Poster #18 Vasovagal syncope in patients with reduced left ventricular function ORAL C Stanton, P Low, D Hodge, WK Shen Rochester, MN, USA Poster #19 An unusual cause of postural syncope AL Birkenfeld, C Schroeder, U Goebel, FC Luft, J Jordan Berlin, Germany Poster #20 Cardiac output assessment during legcrossing and skeletal muscle tensing ORAL assessed by modelflow and inert gas rebreathing. A validation study N van Dijk, J Gisolf, M Linzer, JJ van Lieshout, W Wieling Amsterdam, the Netherlands ORTHOSTATIC HYPOTENSION Poster #21 Autonomic nervous response following rat hindlimb unloading: Investigation on some peripheral districts AL Piepoli, G De Salvatore, JF Desaphy, L Natale, MA De Salvia, CI Mitolo, G Renna, D Conte-Camerino, D Mitolo-Chieppa Bari, Italy Poster #22 Dynamic change of blood pressure and cerebral blood flow in acute phase of the dopamine agonist treatment in de novo Parkinson’s disease SJ Yeh, EY Tu, CC Chiu Taichung, Taiwan Poster #23 Neurohormonal regulation in patients with neurogenic orthostatic hypotension due to diabetes mellitus and other etiologies JL Gilden, A Bolisay, W Tsai, P Hung, N Joshi, SP Singh North Chicago, IL, USA Poster #24 Increased variability of sinus node origin in patients with postural tachycardia syndrome W Singer, WK Shen, TL Opfer-Gehrking, PA Low Rochester, MN, USA Poster #25 Cerebral and brachial blood flow fluctuations: a common etiology? ORAL R Schondorf, R Stein, J Benoit Montreal, Canada THURSDAY, OCTOBER 21, 2004 12:00-14:00 POSTER SESSION 2 CHAIRS: FELICIA AXELROD & JEAN-MICHEL SENARD PEDIATRIC AUTONOMIC DISORDERS -9Poster #26 School refusal due to autonomic imbalance: Psychosomatic aspects of POTS? N Tamura, T Yamamoto, S Naitoh, K Shimazu, K Tamura Iruma-gun, Saitama, Japan Poster #27 SIDS in preterm baby: The role of coupling direction in cardio-respiratory ORAL interaction F Wallois, R Grebe, G Kongolo Amiens, France Poster #28 Vagus nerve stimulation improves severely impaired heart rate variability in a 14-year-old girl with Lennox-Gastaut syndrome S Koenig, E Longin Mannheim, Germany Poster #29 Heart rate variability in children with neurocardiogenic syncope or with symptoms of orthostatic dysregulation during tilt table testing and active standing E Longin, J Reinhard, T Lenz, S Koenig Mannheim, Germany Poster #30 Time course of vagus nerve stimulation effects on cardiac activity in epileptic children M Pruvost, B Zaaimi, P Berquin, R Grebe, F Wallois, V Perlitz Amiens, France PERIPHERAL AUTONOMIC NEUROPATHIES Poster #31 Evidence for denervation hypersensitivity of peripheral cholinergic and ORAL adrenergic nerve fibers in patients with familial dysautonomia A Bickel, H Marthol , FB Axelrod, B Neundoerfer, MJ Hilz Erlangen, Germany Poster #32 Autonomic nervous function in demyelinating and axonal types of GuillainBarre syndrome T Yamamoto, N Tamura, T Abe, S Naito, N Sumita, K Shimazu Iruma-gun, Saitama, Japan Poster #33 Detection of cardiac autonomic neuropathy in insulin-dependent diabetes mellitus A Pavy-Le Traon, S Fontaine, JM Senard, B Guidolin, H Hanaire Toulouse, France Poster #34 Removal of antagonistic antibodies against ganglionic nicotinic receptors ORAL by plasma exchange in a case of severe autonomic failure: a cure for “the hexamethonium man”? C Schroeder, A Birkenfeld, K Heusser, R Kettritz, F Luft, S Vernino, J Jordan Berlin, Germany Poster #35 Proximal sudomotor fiber dysfunction in small fiber neuropathy K Juhasz-Pocsine Little Rock, AR, USA Poster #36 Enteric and cholinergic neuropathy and anti-Hu antibodies without ORAL detectable sensory neuronopathy or underlying malignancy L Weimer, A Dousmanis New York, NY, USA -10Poster #37 ORAL Assessment of temperature perception and sweating in familial dysautonomia B Stemper, F Axelrod, A Bickel, G Wendelschafer-Crabb, W Kennedy, M Hilz Erlangen, Germany Poster #38 Idiopathic pure sudomotor failure: anhidrosis due to deficits in cholinergic ORAL transmission Y Nakazato, N Tamura, A Ohkuma, K Yoshimaru, K Shimazu Iruma-gun, Saitama, Japan CENTRAL AUTONOMIC NERVOUS SYSTEM DISORDERS Poster #39 Does the electrocardiogram have biological noise from the stomach, skin, and other organs? E Lerner, J Peusher Amsterdam, the Netherlands Poster #40 Agalsidase beta improves cerebral autoregulation in Fabry disease MJ Hilz, EH Kolodny, M Tutaj, M Brys, H Szczepanska, B Stemper, H Marthol Erlangen, Germany Poster #41 Laterization of autonomic functions following surgery in intractable epileptics KK Deepak, S Mukharjee, M Tripathi, PS Chandra New Delhi, India Poster #42 The implantation and stimulation of posterior hypothalamus does not affect the circadian rhythm of core body temperature in chronic intractable cluster headache patients G Pierangeli, G Barletta, M Leone, R Vetrugno, P Guaraldi, F Magnifico, S Cevoli, P Montagna, G Bussone, P Cortelli Bologna, Italy Poster #43 Influence of deep brain stimulation on central autonomic regulation ORAL A Lipp, T Trottenberg, J Jordan, G Arnold Berlin, Germany Poster #44 Changes in the central sympathetic control of the circulation in diabetic rats APM Yusof Penang, Malaysia Poster #45 The hypothalamus in multiple system atrophy: preliminary observations ORAL E Benarroch, A Schmeichel, P Low, J Parisi Rochester, MN, USA Poster #46 Hemodynamic effects of oral L-dopa in de novo parkisonian patients N Sumita, T Yamamoto, S Naitoh, T Abe, Y Nakazato, N Tamura, K Shimazu Iruma-gun, Saitama, Japan Poster #47 Cutaneous sympathetic function in patients with Parkinson’s disease and ORAL multiple system atrophy M Asahina, A Suzuki, Y Kikkawa, T Hattori Chiba, Japan Poster #48 Allgrove syndrome: autonomic study in adulthood ORAL G De Joanna, A Salmaggi, F Del Sorbo, C Pantaleoni, A Albanese Naples, Italy -11Poster #49 ORAL Blood pressure after premature ventricular contractions shows sensitively sympathetic neurocirculatory failure in Parkinson’s disease CA Haensch, J Jörg Wuppertal, Germany Poster #50 Cardiovascular autonomic function in post-stroke patients M Dütsch, C Dorfler, M Burger, H Marthol, B Neundörfer, M Hilz Erlangen, Germany Poster #51 Autonomic dysfunction is present in dementia with Lewy bodies L Allan, C Ballard, J Allen, A Murray, A McLaren, RA Kenny Newcastle upon Tyne, United Kingdom Poster #52 Time-domain cross-correlation analysis of cerebral autoregulation in diabetic autonomic neuropathy SJ Yeh, BY Liau, CL Shen, CC Chiu Taichung, Taiwan Poster #53 Limited endoscopic thoracic sympathetic block for hyperhidrosis and facial blushing G Bischof, J Zacherl, P Panhofer, R Jakesz, C Neumayer Vienna, Austria Poster #54 Effect of limited endoscopic thoracic sympathetic block on palmo-plantar hyperhidrosis C Neumayer, J Zacherl, P Panhofer, R Jakesz, G Bischof Vienna, Austria GASTROINTESTINAL/UROGENITAL Poster #55 Changes of gastrointestinal motility in a rat model of diabetes ORAL MA De Salvia, AL Piepoli, D Mitolo-Chieppa Bari, Italy Poster #56 Micturition epilepsy: A rare form of autonomic reflex epilepsy ORAL JW Britton Rochester, MN, USA Poster #57 Autonomic response to rectal distension in controls and in patients with ORAL irritable bowel syndrome S Paranjape, H Mertz, D Robertson, A Diedrich Nashville, TN, USA Poster #58 Urogenital disorders in de novo parkinsonian patients SR De Luka, B Milovanovic, M Svetel, V Kostic Belgrade, Serbia and Montenegro Poster #59 Subtle changes in the involvement of the parasympathetic nervous system ORAL in irritable bowel syndrome (IBS) NP van Orshoven, GI Andriesse, LJ van Schelven, AJ Smout, LMA Akkermans, PL Oey Utrecht, the Netherlands Poster #60 Lower urinary tract function in dementia of Lewy body-type (DLB) R Sakakibara, T Uchiyama, M Asahina, Z Liu, T Yamamoto, T Ito, Y Yamanaka, T Yamanishi, T Hattori Chiba, Japan -12- FRIDAY, OCTOBER 22, 2004 12:00-14:00 POSTER SESSION 3 CHAIRS: ROY FREEMAN & MAX HILZ SYNCOPE/ORTHOSTATIC INTOLERANCE Poster #61 Body composition better predicts head-up tilt test outcome than ORAL cardiovascular variables JO Fortrat, D Schang, E Bellard, G Leftheriotis, J Victor Angers, France Poster #62 Prevalence and profile of cognitive impairment and dementia in patients ORAL with carotid sinus syndrome (CSS) and carotid sinus hypersensitivity (CSH) R Pearce, S Kerr, C Ballard, RA Kenny Newcastle upon Tyne, United Kingdom Poster #63 Disturbed plasma volume regulation in women with premenstrual syndrome R Rosenfeld, D Livne, S Lavi, L Dayan, G Jacob Haifa, Israel Poster #64 Autonomic nervous system profile in the premenstrual syndrome (PMS) R Rosenfeld, D Livne, S Lavi, L Dayan, G Jacob Haifa, Israel Poster #65 Hyperadrenergic postural tachycardia syndrome in mast cell activation ORAL disorders C Shibao, C Arzubiaga, J Roberts III, JA Oates, D Robertson, I Biaggioni Nashville, TN, USA Poster #66 Prospective evaluation of orthostatic hypotension: relationship of symptom ORAL grade to CASS C Schrezenmaier, J Gehrking, S Hines, L Benrud-Larson, P Low, P Sandroni Rochester, MN, USA Poster #67 Orthostatic dyspnea: a novel symptom of orthostatic hypotension ORAL C Gibbons, R Freeman Boston, MA, USA HYPERTENSION AND OTHER CARDIOVASCULAR DISORDERS Poster #68 Cardiovascular risk predictors for sudden heart death by patients with Parkinson’s disease B Milovanovic, S deLuka, M Svetel, V Kostic, M Krotin, J Vucicevic, A Milicevic, V Bisenic, A Milovanovic, N Stankovic New Belgrade, Serbia, Montenegro, Europe Poster #69 Sympathetic hypertensive syndrome (SHS): A new indication of surgically curable hypertension in sympathetic surgery EL Kao, CC Lin Tainan, Taiwan Poster #70 Ventricular repolarisation dynamicity: a new discriminant marker to identify obese patients at risk of drug-induced torsades de pointes A Pathak, M Galinier, J Fourcade, JL Montastruc, JM Senard Toulouse, France -13Poster #71 ORAL Enhanced MAPK-dependent ET-1 production is involved in endothelial dysfunction in resistance vessels of SHR with metabolic insulin resistance MA Potenza, FL Marasciulo, G Siro-Brigiani, D Mitolo Chieppa, MJ Quon, M Montagnani Bari, Italy Poster #72 Non-invasive cardiac output in patients with ischemic heart disease LWJ Bogert, EJ van Lieshout, MB Vroom, BAJM de Mol, J van Goudoever, KH Wesseling, JJ van Lieshout Amsterdam, the Netherlands Poster #73 Effect of enalapril on blood pressure and left ventricular mass in patients with primary autonomic failure S Maule, M Tredici, T Grosso, A Milan, C Pugni, C Bertello, A Verhovez, F Veglio Turin, Italy Poster #74 Endothelial nitric oxide: pharmacogenetics and role in hypertension ORAL A Gamboa, C Shibao, A Diedrich, S Paranjape, JA Phillips, I Biaggioni Nashville, TN, USA Poster #75 Alteration of circadian blood pressure and its correlations to arteriosclerosis and cognitive dysfunction in Parkinson's disease C Muhl, J Jörg Wuppertal, Germany Poster #76 Heart rate variability and Q-SART in a multiethnic population: preliminary findings A Grandinetti, D Chow, I Schatz, P Low Honolulu, HI, USA EXPERIMENTAL MODELS Poster #77 Animal model for the respiratory effects of vagus nerve stimulation in ORAL epileptic children B Zaaimi, M Pruvost, P Berquin, R Grebe, F Wallois Amiens, France Poster #78 The effects of spinal manipulation on control of peripheral and cardiovascular autonomic function during cold pressor response D Grimm, B Cunningham, J Burke Seneca Falls, NY, USA Poster #79 Autonomic nervous system and blood pressure regulation in RGS2-deficient ORAL mice V Gross, J Tank, M Obst, R Plehm, KJ Blumer, A Diedrich, J Jordan, FC Luft Berlin, Germany Poster #80 Heterozygous dopamine transporter knockout (DATKO) mice display altered ORAL circadian rhythm in striatal NO2- and NO3- but no difference in L-DOPAenhancement K Itokawa, A Ohkuma, N Araki, N Tamura, K Shimazu, I Sora, K Ikeda, G Uhl Iruma-gun, Saitama, Japan PHARMACOLOGY AND TREATMENT Poster #81 Spinal cord stimulation in the treatment of orthostatic dysfunction ORAL A Diedrich, P Konrad, A Gamboa, I Biaggioni, RM Robertson, D Robertson Nashville, TN, USA -14Poster #82 ORAL Poster #83 ORAL Poster #84 Poster #85 ORAL OTHER Poster #86 Poster #87 ORAL Poster #88 Poster #89 Poster #90 Poster #91 ORAL Poster #92 ORAL Poster #93 ORAL Modafinil elicits adrenergic cardiovascular activation I Taneja, A Diedrich, B Black, D Robertson Nashville, TN, USA Intestinal obstruction associated with oral midodrine: first case report A Pathak, P Debats, JL Montastruc, JM Senard Toulouse, France Did the heat wave during the summer of 2003 in France modify efficacy of drugs prescribed in patients with neurogenic orthostatic hypotension? A Pathak, M Lapeyre-Mestre, JL Montastruc, JM Senard Toulouse, France Safety of drugs used for orthostatic hypotension: a prospective observational study in outpatients A Pathak, V Raoul, JL Montastruc, JM Senard Toulouse, France Semi-quantitative evaluation of autonomic dysfunction in extrapyramidal disorders – the QuickAnamnesisManager (QAM) T Ziemssen, M Suess, F Suess, O Stolle, A Hellich, H Reichmann Dresden, Germany Effect of posterior hypothalamic electrodes implantation on cardiovascular reflexes P Guaraldi, M Leone, D Grimaldi, G Barletta, G Pierangeli, G Bussone, P Cortelli Modena, Italy Effect of aging on the cardiovascular homeostatic in healthy women O Nevo, S Lavi, R Rosenfeld, I Thaler, N Hirshoren, L Dayan, G Jacob Haifa, Israel Lin-Telaranta classification in sympathetic surgery: one-year clinical experience of 464 cases EL Kao, CC Lin, T Telaranta Tainan, Taiwan Enhanced sympathetic activity in bruxism patients H Marthol, J Jacke, S Reich, KH Lechner, MJ Hilz Erlangen, Germany Life satisfaction and depressive symptoms in patients with multiple system atrophy L Benrud-Larson, P Sandroni, A Schrag, P Low Rochester, MN, USA Vestibular nerve stimulation modulates muscle sympathetic nerve activity in humans A Voustianiouk, A Diedrich, D Ogorodnikov, H Macdougall, T Raphan, I Biaggioni, B Cohen, H Kaufmann New York, NY, USA Heart rate variability in HIV associated lipodystrophy D Chow, A Grandinetti, R Wood, I Schatz, P Low Honolulu, HI, USA -15Poster #94 ORAL Poster #95 Palmar skin blood flow and temperature responses throughout endoscopic sympathectomy surgery S Davis, D Meyer, S Dellaria, C Crandall Dallas, TX, USA Autonomic profile in migraine H Benjelloun, L Coghlan, I Slaoui, M Benomar Rabat, Morocco SATURDAY, OCTOBER 23, 2004 8:00-9:30 AM POSTER SESSION 4 CHAIRS: HORACIO KAUFMANN & JOHANNES VAN LIESHOUT BAROREFLEX Poster #96 ORAL Poster #97 Poster #98 Poster #99 Poster #100 ORAL Poster #101 Poster #102 ORAL Poster #103 TRAVEL FELLOWSHIP AWARDEE (SPONSORED BY THE AMERICAN AUTONOMIC SOCIETY) Baroreflex control of muscle sympathetic nerve activity in the postural orthostatic tachycardia syndrome N Muenter Swift, N Charkoudian, R Dotson, G Suarez, P Low Rochester, MN, USA HIV infection, AIDS and baroreflex function G Raimondi, S Sacco, S Greco, S Cicalini, E Bumis, P Noto, N Petrosillo, C Saltini, JM Legramante Rome, Italy Baroreflex sensitivity during postural stress B Westerhof, J Gisolf, J Karemaker, K Wesseling, N Secher, H van Lieshout Amsterdam, the Netherlands Trigonometric regressive spectral analysis (TRS) - a new approach for baroreflex analysis T Ziemssen, H Rüdiger Dresden, Germany Baroreflex resetting in obstructive sleep apnoea - a mechanism for promoting hypertension V Cooper, C Bowker, M Elliott, S Pearson, R Hainsworth Leeds, United Kingdom Carotid artery stiffening in patients after atrial switch repair of transposition of great arteries is not associated with impaired autonomic function B Mersich, P Studinger, Z Lénárd, K Kádár, I Hartyánszky, V Oprea, M Kollai Budapest, Hungary Effect of gender on baroreflex regulation J Tank, K Heusser, A Diedrich, F Luft, J Jordan Berlin, Germany Arterial baroreflex control of heart rate during exercise with and without cardio-selective 1-adrenergic blockade P Raven, S Ogoh, M Dalsgaard, C Yoshiga, E Dawson, D Keller, N Secher Fort Worth, TX, USA -16Poster #104 Enhancement of controlling the vascular unloading condition with continuous adjustment of set point J Fortin, R Gruellenberger, A Hacker, P Wach, F Skrabal Graz, Austria Poster #105 Restoration of baroreflex sensitivity and cardiovagal tone in old mice by ORAL short-duration antioxidant therapy E Lazartigues, N Maheshwari, C Whiteis, H Stauss, R Davisson, F Abboud, M Chapleau Iowa City, IA, USA Poster #106 Effect of renal transplantation on cardiovagal autonomic function in children with end-stage renal disease Z Lénárd, B Mersich, P Studinger, G Reusz, V Vincze, M Kollai Budapest, Hungary Poster #107 The effects of nitric oxide and carbon monoxide on cardiovascular ORAL regulation in the nucleus tractus solitarii of rats CS Tung, WC Lo, M Hsiao, CJ Tseng Taipei, Taiwan, ROC Poster #108 The beneficial effect of mildronate on cardiovascular autonomic function in chronic heart failure D Voita, I Skarda, V Dzerve, N Kukulis, I Kalvins, Z Rugaja Riga, Latvia Poster #109 Altered baroreflex estimates in congenital central hypoventilation syndrome ORAL (CCHS, ondine’s curse) A Girard, D Laude, H Trang, JL Elghozi Paris, France EXERCISE AND INTEGRATIVE AUTONOMIC PHYSIOLOGY Poster #110 Bronchodilation following deep inspiration is related to overriding ORAL cholinergic airway tone among subjects with tetraplegia AM Spungen, M Radulovic, JM Wecht, GJ Schilero, WA Bauman, M Lesser Bronx, NY, USA Poster #111 Functional sympathetic innervation of human lungs: a model among ORAL subjects with spinal cord injury G Schilero, M Radulovic, A Spungen, J Wecht, W Bauman, M Lesser Bronx, NY, USA Poster #112 Fluid redistribution in the macro-circulation despite calf edema and overall fluid deficit in healthy subjects after six hours of sitting FJ Baisch, LF Baisch, W Koch, K Kroeger, HJ Lindner Cologne, Germany Poster #113 Effect of exercise on cardio-vagal autonomic function in normotensive ORAL offspring of hypertensive parents P Studinger, Z Lénárd, B Mersich, G Pavlik, M Kollai Budapest, Hungary Poster #114 Otolithic activation fails to elicit vasoconstriction in visceral arteries in older ORAL humans C Sauder, N Kuipers, E McHugh, U Leuenberger, C Ray Hershey, PA, USA SPECTRAL ANALYSIS AND MODELING -17Poster #115 ORAL Interaction of heart rate and sympathetic nerve outflow in humans I Bonyhay, R Freeman Boston, MA, USA Poster #116 Cardiac autonomic control during working time in shift and day work ORAL F Barbic, F Perego, F Dipaola, A Diana, A Galli, C Mantovani, P Seghizzi, A Malliani, R Furlan Milan, Italy Poster #117 Degree of diminution in vagal-cardiac activity predicts sudden death in familial dysautonomia when resting tachycardia is absent TT Schlegel, H Marthol, M Tutaj, S Buechner, D Berlin, FB Axelrod, MJ Hilz Erlangen, Germany Poster #118 Comparison of Fourier and wavelet based estimates of heart rate variability during tilt J Weir, J Wecht, M Nordseth, E Racz, A Spungen, W Bauman Des Moines, IA, USA Poster #119 Nonlinear dynamic analysis of blood pressure variability in diabetics with autonomic neuropathy using approximate entropy CC Chiu, SJ Yeh, YL Liu, BY Liau Taichung, Taiwan, R.O.C. Poster #120 Relationship between sympatho-vagale equilibrium and coupling of respiration and cardiovascular system R Grebe, V Perlitz, F Wallois Amiens, France LABORATORY EVALUATION Poster #121 Expression of p75 nerve growth factor receptor in sweat glands of patients ORAL with anhidrosis T Abe, K Miyamoto, S Matsubara, T Mizutani, H Hayashi, K Shimazu Iruma-gun, Saitama, Japan Poster #122 Effect of length of storage and storage condition on acetylcholine chloride solutions D Sletten, K Nickander, P Low Rochester, MN, USA Poster #123 Does dysautonomia explain pupillary abnormalities in Myasthenia Gravis? K Chémali, R Shields Cleveland, OH, USA Poster #124 Sensitivity of the mean heart rate range and the E:I ratio in assessing the heart rate response to deep breathing RW Shields, Jr Cleveland, OH, USA Poster #125 When standing up middle cerebral artery velocity decreases more than can be accounted for by the reduction in the arterial carbon dioxide concentration RV Immink, NH Secher, CM Roos, F Pott, PL Madsen, JJ Van Lieshout Amsterdam, the Netherlands Poster #126 Lack of influence of St. John’s Wort on norepinephrine turnover and ORAL monoamine oxidase in humans C Schroeder, A Birkenfeld, D Goldstein, S Haertter, F Luft, J Jordan Berlin, Germany -18- This program is sponsored in part by unrestricted educational grants provided by the following. This support is gratefully acknowledged. Main Sponsor: Finapres Medical Systems Sponsors: AstraZeneca CN Systems Eli Lilly GlaxoSmithKline KNAW Vitatron