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Biosequences, Proteins, and Enzymes BRENDA – Enzyme database http://www.brenda.uni-koeln.de 45,000 enzymes from 4,100 Enzyme Classification (E.C.) numbers See the Enzyme Structures Database for an example of the use of E.C. numbers. http://www.ebi.ac.uk/thornton-srv/databases/enzymes PDB – Protein Data Bank http://www.rcsb.org/pdb 45,000 Protein crystal structures and some NMR solution structures 3D Viewers and Tools Swiss PDB Viewer – Recommended free tool and viewer. http://www.expasy.ch/spdbv/ Cn3D – Also a free tool and viewer. RasMol NCBI – National Center for Biotechnology Information http://www.ncbi.nlm.nih.gov Literature Databases PubMed – Medline http://www.ncbi.nlm.nih.gov/PubMed/ OMIM – Online Mendelian Inheritance in Man http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim Molecular Databases GenBank – nucleotide sequences Protein – protein sequences MMDB (Molecular Modeling Database) – structures Gene – genes Tools BLAST – Basic Local Alignment Search Tool EBI – European Bioinformatics Institute http://www.ebi.ac.uk Molecular Databases Tools EMBL-Bank – genomics UniProt – nucleotide sequences ArrayExpress – protein sequences Ensembl – macromolecules ExPASy: Proteomics Server http://expasy.org Expert Protein Analysis System